Results 171 to 180 of about 4,982,676 (293)

Spatial and Temporal Heterogeneity of Macrophage Efferocytosis in Tumors: Emerging Implications for Immunotherapy Biomarkers and Therapeutic Timing

Cancer Medicine, Volume 15, Issue 9, September 2026.
ABSTRACT Resistance to immune checkpoint blockade (ICB) remains a major barrier in cancer therapy, reflecting the fact that tumor immunity is governed not only by cell type abundance but also by spatial organization and temporal dynamics within the tumor microenvironment (TME).
Shanyi Li, Jilei Li, Zhenyu Zhang, Sizhe Wang, Chunzheng Ma   +4 more
wiley   +1 more source

Supplementary Material for: Rab27 a regulates dendritic cell immune tolerogenic capacity

figshare admin karger, Wu Y.-P., Peng S.-W., Bin D.H., Wang Z.-Y., Liu Q., Wu Y.-D., Peng K.-P., Tan S.-L., Yang P.-C., Tian G.-T.   +10 more
openalex   +2 more sources

Advances and challenges in immunotherapy for intrahepatic cholangiocarcinoma based on the tumour immune microenvironment

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
This review integrates ICC‐specific and broader BTC evidence to define how desmoplastic stroma, immune‐cell crosstalk, metabolic remodelling, and molecular heterogeneity shape immunotherapy response and resistance. It highlights biomarker‐guided, mechanism‐based combinations while emphasizing the limited maturity of ICC‐specific evidence for emerging ...
Mengyao Chen, Shuofan Jin, Yuxuan Zhou, Jinkai Tong, Yufan Zhao, Quanjun Yang   +5 more
wiley   +1 more source

Advancing Type 1 Diabetes Treatment: 3 PM‐Oriented Innovations in Islet Transplantation and Biomaterial Engineering

Diabetes/Metabolism Research and Reviews, Volume 42, Issue 6, September 2026.
ABSTRACT Type 1 Diabetes (T1D) is an autoimmune disorder marked by the immune‐mediated destruction of pancreatic β‐cells, resulting in insulin deficiency and dysregulated glucose control. Current therapies—such as insulin replacement and artificial pancreas systems—manage symptoms but fail to restore endogenous β‐cell function or halt disease ...
Fatemeh Sabet Sarvestani, Ramin Yaghobi, Mohsen Khosravi Maharlooei, Mehdi Golshan, Mohammad Hossein Karimi   +4 more
wiley   +1 more source

Intestinal Epithelial Memory: From Inflammatory Imprinting to Metabolite‐Shaped Immune Tolerance

Barrier Immunity, Volume 2, Issue 3, Page 119-130, September 2026.
ABSTRACT Intestinal epithelial cells are rapidly renewing barrier cells that maintain compartmentalization between the luminal environment and the mucosal immune system through epithelial transport, antimicrobial defense, secretory programs, and cytokine‐mediated communication.
Wenjing Yang, Tianming Yu, Yingzi Cong
wiley   +1 more source

Human tolerogenic dendritic cell subtypes exert divergent effects on induction of cytotoxic CD4⁺ T cells. [PDF]

Front Immunol
Barran G, Naamane N, Baru AM, Anderson AE, Falconer J, Hilkens CMU.   +5 more
europepmc   +1 more source

Exploring the Immunomodulatory Moonlighting Activities of Acute Phase Proteins for Tolerogenic Dendritic Cell Generation. [PDF]

Front Immunol, 2018
Serrano I, Luque A, Aran JM.
europepmc   +1 more source

Tolerogenic dendritic cells modulate macrophage inflammatory response in Ulcerative colitis: role of IL-1RN

Yan Xu, Huidong Zhang, Xianjie Chen, Shanci Wang, Liang Peng, Juan He, Lingjun Meng   +6 more
openalex   +1 more source

Lonicerae Japonicae Flos as a Dietary Natural Product: Bioactive Constituents, Gut Health Modulation, and Therapeutic Potential in Ulcerative Colitis and Colorectal Cancer

Food Science &Nutrition, Volume 14, Issue 9, September 2026.
Bioactive constituents, mechanisms of action, and potential applications of Lonicerae Japonicae Flos as a dietary natural product for promoting gut health and managing ulcerative colitis and colorectal cancer. ABSTRACT Lonicerae Japonicae Flos (LJF), a traditional Chinese herb with applications in both medicine and nutrition, has emerged as a promising
Xiaoyu Huang, Letian Zhang, Zenghui Shi, Ni Zhu, Yifei Liu, Yanhong Zhou   +5 more
wiley   +1 more source

Role of USP7 in the regulation of tolerogenic dendritic cell function in type 1 diabetes. [PDF]

Cell Mol Biol Lett
Khan FU, Khongorzul P, Gris D, Amrani A.
europepmc   +1 more source