Results 261 to 270 of about 4,982,676 (293)

Nebulized bone marrow-derived stem cell supernatant induces tolerogenic dendritic cells via upregulation of FOXO3 for EAE treatment

Junfeng Wu, Zhixin Qiao, Yanping Wang, Sifan Zhang, Jiayu Ji, Xiaoru Ma, Xiyu Zhang, Xin Xiu, Xiujuan Lang, Xijun Liu, Bo Sun, H L Li, Hulun Li   +12 more
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Erratum to “Identification of significant hub genes and pathways associated with metastatic breast cancer and tolerogenic dendritic cell via bioinformatics analysis” [Comput. Biol. Med. 184, (January 2025), 109396]

Kirstie Wong Chee Ching, Noor Fatmawati Mokhtar, Gee Jun Tye   +2 more
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Gene expression of CD4+ T cells of rheumatoid arthritis patients primed by mature or tolerogenic dendritic cells

Gabrielle Barran, Najib Naamane, Abdul Mannan Baru, Amy E. Anderson, Jane Falconer, Catharien M.U. Hilkens   +5 more
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Tolerogenic Dendritic Cells in Autoimmunity and Inflammatory Diseases

Trends in Immunology, 2021
Dendritic cells (DCs), the most efficient antigen-presenting cells, are necessary for the effective activation of naïve T cells. DCs can also acquire tolerogenic functions in vivo and in vitro in response to various stimuli, including interleukin (IL)-10, transforming growth factor (TGF)-β, vitamin D3, corticosteroids, and rapamycin. In this review, we
Esteban Ballestar, Octavio Morante-Palacios, Eva Martinez-Caceres   +2 more
exaly   +3 more sources

Life and death of tolerogenic dendritic cells

Trends in Immunology, 2023
In contrast to conventional dendritic cells (cDCs) that are constantly exposed to microbial signals at anatomical barriers, cDCs in systemic lymphoid organs are sheltered from proinflammatory stimulation in the steady state but respond to inflammatory signals by gaining specific immune functions in a process referred to as maturation.
Jessica, Bourque, Daniel, Hawiger
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Modulation of tolerogenic dendritic cells and autoimmunity

Seminars in Cell & Developmental Biology, 2015
A key function of dendritic cells (DCs) is to induce either immune tolerance or immune activation. Many new DC subsets are being recognized, and it is now clear that each DC subset has a specialized function. For example, different DC subsets may express different cell surface molecules and respond differently to activation by secretion of a unique ...
Sun Jung, Kim, Betty, Diamond
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Potential of tolerogenic dendritic cells for transplantation

Seminars in Immunology, 2001
Dendritic cells (DC) are professional antigen (Ag)-presenting cells considered traditionally as the passenger leukocytes that, after migration from transplanted tissues, stimulate allospecific naive T cell responses and trigger acute rejection. However, there is recent evidence that, besides their role in central T lymphocyte deletion in the thymus, DC
A E, Morelli, H, Hackstein, A W, Thomson
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Tolerogenic dendritic cells

Current Opinion in Organ Transplantation, 2012
We discuss the use of tolerogenic dendritic cells (TolDCs) as a therapeutic tool in solid organ transplantation, with particular emphasis on recent experimental and preclinical data supporting the clinical translation of TolDC therapy.TolDC have been successfully used in rodents to promote long-term allograft survival.
Gaelle, Beriou, Aurelie, Moreau, Maria C, Cuturi   +2 more
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Regulatory Multitasking of Tolerogenic Dendritic Cells – Lessons Taken from Vitamin D3-Treated Tolerogenic Dendritic Cells [PDF]

Frontiers in Immunology, 2013
Tolerogenic dendritic cells (DCs) work through silencing of differentiated antigen-specific T cells, activation and expansion of naturally occurring T regulatory cells (Tregs), transfer of regulatory properties to T cells, and the differentiation of naïve T cells into Tregs.
Bart O Roep, Tatjana Nikolic
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What is the Role of Antigen-Processing Mechanisms in Autologous Tolerogenic Dendritic Cell Therapy in Organ Transplantation?

Immunotherapy, 2011
Injection of autologous tolerogenic dendritic cells is a promising strategy to diminish the burden of harmful immunosuppression in clinical transplantation. We discuss the immunoregulatory mechanisms triggered by this approach.
Maria Cristina Cuturi, Marcelo Hill, Mercedes Segovia   +2 more
exaly   +2 more sources