Results 271 to 280 of about 4,982,676 (293)

Tolerogenic dendritic cells for autoimmune disease and transplantation

Annals of the Rheumatic Diseases, 2008
Dendritic leucocytes are professional antigen-presenting cells with inherent tolerogenic properties and are regarded as critical regulators of innate and adaptive immunity. Modification of dendritic cells (DCs) in the laboratory can enhance and stabilise their tolerogenic properties. Numerous reports suggest that such immature, maturation-resistant or "
A W, Thomson, P D, Robbins
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Generating tolerogenic dendritic cells with neuropeptides

Human Immunology, 2009
Induction of antigen-specific tolerance is critical to prevent autoimmunity, to maintain immune homeostasis, and to achieve transplant tolerance. In addition to their classic role as sentinels of the immune response, dendritic cells (DCs) play important roles in maintaining peripheral tolerance through the induction/activation of regulatory T (Treg ...
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Use of Rapamycin in the Induction of Tolerogenic Dendritic Cells

2008
Rapamycin (RAPA), a macrocyclic triene antibiotic pro-drug, is a clinically-utilized 'tolerance-sparing' immunosuppressant that inhibits the activity of T, B, and NK cells. Furthermore, maturation-resistance and tolerogenic properties of dendritic cells (DC) can be supported and preserved by conditioning with RAPA. Propagation of murine bone marrow (BM)
Ryan, Fischer, Heth R, Turnquist, Timuçin, Taner, Angus W, Thomson   +3 more
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Tolerogenic dendritic cells and the quest for transplant tolerance

Nature Reviews Immunology, 2007
In recent years, there has been a shift from the perception of dendritic cells (DCs) solely as inducers of immune reactivity to the view that these cells are crucial regulators of immunity, which includes their ability to induce and maintain tolerance.
Adrian E, Morelli, Angus W, Thomson
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Tolerogenic Dendritic Cells: The Ins and Outs of Outcome

Journal of Immunotherapy, 2006
Recent studies point to an important role for dendritic cells (DCs) in the induction of peripheral tolerance, revealing that the maturation and/or activation state of DCs might be a control point for the induction of peripheral tolerance. Recent progress in our understanding of the mechanisms mediating immune tolerance indicates them to be far more ...
Bao-Guo, Xiao, Yu-Min, Huang, Hans, Link
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Tolerogenic Dendritic Cells for Type 1 Diabetes

Immunotherapy, 2013
Evaluation of: Pujol-Autonell I, Ampudia RM, Monge P et al. Immunotherapy with tolerogenic dendritic cells alone or in combination with rapamycin does not reverse diabetes in NOD mice. ISRN Endocrinol. doi:10.1155/2013/346987 (2013) (Epub ahead of print).
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Regulatory Macrophages and Tolerogenic Dendritic Cells in Myeloid Regulatory Cell-Based Therapies

International Journal of Molecular Sciences, 2021
Aurélie Moreau
exaly  

The Epigenetic Reader Protein SP140 Regulates Dendritic Cell Activation, Maturation and Tolerogenic Potential

Current Issues in Molecular Biology, 2023
Mohammed Ghiboub, Wouter de Jonge, Menno de Winther   +2 more
exaly  

Tolerogenic Dendritic Cells Induce Apoptosis-Independent T Cell Hyporesponsiveness of SARS-CoV-2-Specific T Cells in an Antigen-Specific Manner

International Journal of Molecular Sciences, 2022
Ibo Janssens, Nathalie Cools, Benson Ogunjimi   +2 more
exaly  

Therapeutic effects of tolerogenic dendritic cells

Nature Reviews Rheumatology, 2010
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