Results 221 to 230 of about 17,602,436 (258)

Beyond knowledge: Cultivating noncognitive skills and attributes through anatomy education

Anatomical Sciences Education, EarlyView.
Abstract Anatomy education has historically prioritized cognitive knowledge acquisition and technical skills, such as spatial awareness and manual dexterity. Noncognitive attributes, essential for early‐stage learners, such as social skills, motivation, emotional intelligence, self‐regulation, self‐efficacy, and resilience, have remained comparatively ...
Renato Lopes Previdelli, Sarah Beth Channon   +1 more
wiley   +1 more source

Interaction between toll-like receptor 4 polymorphism and abdominal obesity on ovarian cancer risk in Chinese women. [PDF]

BMC Womens Health
Zhu J, Yang B, Zhai X, Ni F, Tao D, Tan C.   +5 more
europepmc   +1 more source

Recent Non‐Suicidal Self‐Injury in Autistic Adolescents and Adults: Characteristics, Clinical Correlates and Suicidal Thoughts and Behaviors

Autism Research, EarlyView.
ABSTRACT Non‐suicidal self‐injury (NSSI) is prevalent among autistic adolescents and adults, yet research on its clinical characteristics, functions, and association with suicidal thoughts and behaviors (STBs) in this population remains limited. This study compared these domains between autistic adolescents and adults with and without recent NSSI.
Safaa Eldeeb, Ligia Antezana, Caitlin M. Conner, Kelly B. Beck, Sarah E. Victor, Aliona Tsypes, Lori N. Scott, Carla A. Mazefsky   +7 more
wiley   +1 more source

The innate immune response in SARS-CoV2 infection: focus on toll-like receptor 4 in severe disease outcomes. [PDF]

Front Immunol
Maggi E, Landolina N, Mariotti FR, Munari E, Tumino N, Vacca P, Azzarone B, Moretta L.   +7 more
europepmc   +1 more source

Repeated intradermal lipopolysaccharide challenge responses in healthy volunteers: Implications for clinical pharmacology studies

British Journal of Clinical Pharmacology, EarlyView.
Aim Intradermal application of lipopolysaccharide (LPS), a Toll‐like receptor 4 agonist, induces a local inflammatory response and is used as a human challenge model to evaluate the pharmacodynamics of investigational medicinal products. While currently applied in a single, parallel‐group setting, alternative within‐subject designs involving repeated ...
Alexandra A. J. Sillé, Juliette A. van den Noort, Iva Lelios, Diana R. Pereira, Marzia A. Scelsi, Erica S. Klaassen, Philipp Schoenenberger, Naomi B. Klarenbeek, Pierre‐Eric Juif, Pascal Espie, Manon A. A. Jansen, Matthijs Moerland, Richard W. D. Welford   +12 more
wiley   +1 more source

Toll-like receptor 4 induces trained innate immune tolerance in the heart in a model of stress-induced cardiomyopathy. [PDF]

Cardiovasc Res
Lim KRQ, Amrute J, Kovacs A, Diwan A, Williams DL, Mann DL.   +5 more
europepmc   +1 more source

Lost and found in translation: the value of the human imiquimod model

British Journal of Clinical Pharmacology, EarlyView.
Topical imiquimod (IMQ), a Toll‐like receptor (TLR) 7 agonist, induces transient cutaneous inflammation and is widely used in preclinical research as a ‘psoriasis‐like’ mouse model. However, accumulating evidence indicates substantial divergence between IMQ‐driven biology and human plaque psoriasis pathogenesis.
Anouk C. Meijs, Juliette A. van den Noort, Salma Assil, Naomi B. Klarenbeek, Matthijs Moerland, Tessa Niemeyer‐van der Kolk, Robert Rissmann   +6 more
wiley   +1 more source

Necrotizing Enterocolitis: A Comprehensive Review on Toll-like Receptor 4-Mediated Pathophysiology, Clinical, and Therapeutic Insights. [PDF]

Biomedicines
Ishiyama A, Jang HS, Dintaman JM, Duess JW, Tragesser C, Sodhi CP.   +5 more
europepmc   +1 more source

Extracellular vesicles from mesenchymal stromal cells primed with synthetic toll-like receptor 4 agonists treat hematopoietic acute radiation syndrome. [PDF]

Stem Cells Transl Med
Kink JA, Forsberg MH, Krismer DM, Thickens AS, Chinnadurai R, Chen AS, Chacko DJ, Graham M, Hematti P, Capitini CM.   +9 more
europepmc   +1 more source

Activation of chicken macrophages by isomalto/malto-polysaccharide (IMMP) is facilitated by toll-like receptor 4 (TLR4). [PDF]

Poult Sci
Ijaz A, Putman M, Broere F, Rutten VPMG, Jansen CA, Veldhuizen EJA.   +5 more
europepmc   +1 more source