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Regulation of adipogenesis by toll-like receptor 5 pathway
2016Toll-like receptor 5 (TLR5) recognizes the bacterial product, flagellin. Its activation leads to cytokine production that is important for host defense against invading pathogens. In spite of the pro-inflammatory nature of TLR5, deficiency of TLR5 exacerbated metabolic dysfunction in diet-induced obese mouse model (Gewirtz et al. Science, 328: 228-231,
YIU, JHC, LI, J, Xu, A, Woo, WHC
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The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5
Nature, 2001The innate immune system recognizes pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, but not on the host. Toll-like receptors (TLRs) recognize PAMPs and mediate the production of cytokines necessary for the development of effective immunity.
F, Hayashi +9 more
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Increased Toll-like receptor 5 expression indicates esophageal columnar dysplasia
Virchows Archiv, 2013Toll-like receptor 5 (TLR5) is an immune receptor, which recognizes bacterial flagellin. Increased expression has been reported in various premalignant and malignant lesions indicating a role in carcinogenesis. We assessed the expression of TLR5 in normal esophageal squamous epithelium, Barrett's esophagus with and without dysplasia, and in esophageal ...
Kauppila Joonas +6 more
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Regulation of osteoclastogenesis by toll-like receptor 5
Bone Abstracts, 2013Ali Kassem +4 more
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Toll-Like Receptor 5 as a Novel Receptor for Fungal Zymosan
2023Stefanie Reuter +4 more
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Obesity, Inflammation, Toll-Like Receptor 4 and Fatty Acids
Nutrients, 2018Philip Calder, Marcelo Macedo Rogero
exaly