Results 91 to 100 of about 414,010 (359)

Endothelial toll-like receptor 4 maintains lung integrity via epigenetic suppression of p16INK4a. [PDF]

open access: yes, 2019
We previously reported that the canonical innate immune receptor toll-like receptor 4 (TLR4) is critical in maintaining lung integrity. However, the molecular mechanisms via which TLR4 mediates its effect remained unclear.
Ardito, Taylor   +10 more
core   +1 more source

Toll‐Like Receptor 4 Mediated Oxidized Low‐Density Lipoprotein‐Induced Foam Cell Formation in Vascular Smooth Muscle Cells via Src and Sirt1/3 Pathway [PDF]

open access: gold, 2021
Zhongli Chen   +10 more
openalex   +1 more source

Advances in Bioprinting to Model Immune‐Mediated Skin Diseases

open access: yesAdvanced Healthcare Materials, EarlyView.
This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández   +4 more
wiley   +1 more source

TOLL LIKE RECEPTOR 4 (TLR4) AND DEMYELINATION

open access: yesIBRO Neuroscience Reports, 2023
Estefanía Sánchez-Jiménez   +12 more
doaj   +1 more source

Sequence variants of toll like receptor 4 and late-onset Alzheimer's disease.

open access: yesPLoS ONE, 2012
BackgroundToll like receptor 4 (TLR4) has been related to inflammation and beta-amyloid deposition in Alzheimer's disease (AD) brain. No study has explored the association between haplotype-tagging single nucleotide polymorphisms (htSNPs) of TLR4 and AD ...
Yen-Ching Chen   +6 more
doaj   +1 more source

Toll-like receptor 9-positive plasmacytoid dendritic cells promote Th17 immune responses in oral lichen planus stimulated by epithelium-derived cathepsin K [PDF]

open access: gold, 2023
Yuka Miyahara   +14 more
openalex   +1 more source

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

open access: yesAdvanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad   +3 more
wiley   +1 more source

Cell-free synthesis of human toll-like receptor 9 (TLR9): Optimization of synthesis conditions and functional analysis.

open access: yesPLoS ONE, 2019
The Toll-like receptor family belongs to the group of pathogen recognition receptors which is responsible for the discrimination of self and non-self pathogen-associated molecular patterns (PAMP's).
Srujan Kumar Dondapati   +4 more
doaj   +1 more source

Toll-like receptor-3 contributes to the development of aortic valve stenosis [PDF]

open access: hybrid, 2023
Sven Thomas Niepmann   +17 more
openalex   +1 more source

PiP‐Plex: A Particle‐in‐Particle System for Multiplexed Quantification of Proteins Secreted by Single Cells

open access: yesAdvanced Materials, EarlyView.
Detecting proteins secreted by a single cell while retaining its viability remains challenging. A particles‐in‐particle (PiPs) system made by co‐encapsulating barcoded microparticles (BMPs) with a single cell inside an alginate hydrogel particle is introduced.
Félix Lussier   +10 more
wiley   +1 more source

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