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Trends in Molecular Medicine, 2002
A mammalian immune response to microbial organisms requires a series of pattern recognition steps, and nonspecific processes often precede elements of the specific immune system in this process. Molecules such as lipopolysaccharide, peptidoglycan and lipoteichoic acids are relatively conserved, and are recognized in this manner by toll-like receptors ...
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A mammalian immune response to microbial organisms requires a series of pattern recognition steps, and nonspecific processes often precede elements of the specific immune system in this process. Molecules such as lipopolysaccharide, peptidoglycan and lipoteichoic acids are relatively conserved, and are recognized in this manner by toll-like receptors ...
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Toll-Like Receptors and Their Ligands
2002The Toll-like receptors (TLRs) are key molecules involved in the recognition of pathogens by the innate immune system. This family of germ line-encoded receptors has evolved to recognize conserved features of microbes. Currently, 10 TLR family members have been identified in mammals.
G M, Barton, R, Medzhitov
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Annals of Allergy, Asthma & Immunology, 2002
To review the role of mammalian Toll-like receptors (TLRs) in host defense.MEDLINE search and current literature.First, TLRs participate in the recognition of molecular patterns present on microorganisms. Second, TLRs are expressed at the interface with the environment, the site of microbial invasion.
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To review the role of mammalian Toll-like receptors (TLRs) in host defense.MEDLINE search and current literature.First, TLRs participate in the recognition of molecular patterns present on microorganisms. Second, TLRs are expressed at the interface with the environment, the site of microbial invasion.
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Current Opinion in Immunology, 2003
Toll-like receptors (TLRs) are essential in the host defense against microbial pathogens. Individual TLRs recognize distinct structural components of pathogens and evoke inflammatory responses. Recent evidence indicates that TLRs recognize not only bacteria and fungi but also viruses.
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Toll-like receptors (TLRs) are essential in the host defense against microbial pathogens. Individual TLRs recognize distinct structural components of pathogens and evoke inflammatory responses. Recent evidence indicates that TLRs recognize not only bacteria and fungi but also viruses.
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Obesity, Inflammation, Toll-Like Receptor 4 and Fatty Acids
Nutrients, 2018Philip Calder, Marcelo Macedo Rogero
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TOLL-like Receptor 10 Genetic Variation Is Associated with Asthma in Two Independent Samples
American Journal of Respiratory and Critical Care Medicine, 2004Donata Vercelli +2 more
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Lipoprotein Accumulation in Macrophages via Toll-Like Receptor-4–Dependent Fluid Phase Uptake
Circulation Research, 2009Joseph Witztum +2 more
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