Results 261 to 270 of about 363,419 (348)

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

Advanced NanoBiomed Research, EarlyView.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari, Yunhui Min, Eun‐Ju Ko, Doyoung Kwon, Rehan Khan, Young‐Ok Son   +5 more
wiley   +1 more source

5-Methoxytryptophan Protects against Toll-Like Receptor 2-Mediated Renal Tissue Inflammation and Fibrosis in a Murine Unilateral Ureteral Obstruction Model. [PDF]

J Innate Immun
Wu JY, Lee GL, Chueh YF, Kuo CC, Hsu YJ, Wu KK.   +5 more
europepmc   +1 more source

Toll like receptors TLR1/2, TLR6 and MUC5B as binding interaction partners with cytostatic proline rich polypeptide 1 in human chondrosarcoma

, 2017
Karina Galoian, S. S. Abrahamyan, Gor Chailyan, Amir Qureshi, Parthik Patel, Gil Metser, Alexandra Moran, I. K. Sahakyan, Narine Tumasyan, Albert Lee, Tigran K. Davtyan, Samvel Chailyan, Armen A. Galoyan   +12 more
openalex   +2 more sources

Reduced Bone Quality of Sacrum and Lumbal Vertebrae Spongiosa in Toll-like Receptor 2- and Toll-like Receptor 4-Knockout Mice: A Blinded Micro-Computerized Analysis. [PDF]

Biomolecules
Roth K, Pallua JD, Degenhart G, De Zordo T, Kremser C, Reif C, Streif W, Schirmer M.   +7 more
europepmc   +1 more source

[Retracted] Toll‑like receptor 2 downregulates the cholesterol efflux by activating the nuclear factor‑κB pathway in macrophages and may be a potential therapeutic target for the prevention of atherosclerosis. [PDF]

Exp Ther Med
Li Y, Shen S, Ding S, Wang L.
europepmc   +1 more source

Haemophilus influenzaePorin Induces Toll-Like Receptor 2-Mediated Cytokine Production in Human Monocytes and Mouse Macrophages

, 2004
Massimiliano Galdiero, Massimiliano Galdiero, Emiliana Finamore, Fabio Rossano, Maria Elsa Gambuzza, Maria Rosaria Catania, Giuseppe Teti, Angelina Midiri, Giuseppe Mancuso, Angelina Midiri, Giuseppe Mancuso   +10 more
openalex   +1 more source

Dietary Baicalin Supplementation Can Enhance the Growth Performance of Weaned Piglets and Maintain the Intestinal Barrier Integrity

Animal Research and One Health, EarlyView.
This research innovatively illustrates baicalin’s multifaceted mechanisms in enhancing piglets’ intestinal health: modulating bile acid metabolism via probiotics, reinforcing tight junction proteins (ZO‐1/claudin), suppressing TLR4/NF‐κB‐mediated inflammation, whereas promoting growth and reducing diarrhea.
Yuhui Gao, Jie Liu, Rui Yang, Xizhen Fan, Cheng Liang, Xin'e Shi, Jianjun Jin   +6 more
wiley   +1 more source

GSP1-111 Modulates the Microglial M1/M2 Phenotype by Inhibition of Toll-like Receptor 2: A Potential Therapeutic Strategy for Depression. [PDF]

Int J Mol Sci
Kim RE, Mabunga DF, Boo KJ, Kim DH, Han SH, Shin CY, Kwon KJ.   +6 more
europepmc   +1 more source

Dietary Mannan‐Rich Fractions Attenuate Weaning Stress in Piglets via Modulating Gut Microbiota and TLR5/NF‐κB Signaling

Animal Research and One Health, EarlyView.
This study aimed to investigate the potential of a mannan‐rich fraction (MRF) as a dietary intervention to alleviate weaning stress in piglets. Our results revealed that MRF could alleviate weaning stress by modulating the gut microbiota and the TLR5/NF‐κB signaling pathway, offering a novel and sustainable alternative to antibiotic use in swine ...
Yutong Lu, Yiwei Sun, Kun Cai, Pingli He, Gang Lin, Zengkai Qi, Hu Liu, Junshu Yan, Ning Ma   +8 more
wiley   +1 more source

Activation of Toll-like receptor 2 promotes mesenchymal stem/stromal cell-mediated immunoregulation and angiostasis through AKR1C1. [PDF]

Theranostics
Ko JH, Lee HJ, Yoon CH, Choi YR, Ryu JS, Oh JY.   +5 more
europepmc   +1 more source