Results 81 to 90 of about 371,093 (352)
Polymorphisms of toll-like receptor 2 and 4 genes in Chagas disease
Memorias do Instituto Oswaldo Cruz, 2008 The aim of this study was to test the possible implication of toll-like receptor 2 (TLR2) and TLR4 gene polymorphisms in determining the susceptibility to Chagas' disease. Genotypes were determined by polymerase chain reaction-restriction fragment length
German Zafra +5 more
doaj +1 more source
Toll-like receptor 4 mediates tubular inflammation in diabetic nephropathy [PDF]
, 2010 published_or_final_versionThe 15th Medical Research Conference, Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong, 16 January 2010. In Hong Kong Medical Journal, 2010, v. 16 n. 1, suppl. 1, p.
Chan, AWH +5 more
core
Renal failure in experimental sepsis: role of Endothelin and the Toll-like receptor 4 [PDF]
, 2011 Sepsis is the leading cause of renal failure in critically ill patients, but the pathogenesis of septic kidney dysfunction is poorly defined. The current paradigm states that hypoperfusion and excessive renal vasoconstriction results in renal ischemia.
Fenhammar, Johan
core +1 more source
Role of toll-like receptor 4 in diabetic retinopathy
Pharmacological Research, 2022 Diabetic retinopathy (DR) is the most frequent microvascular complication of diabetes mellitus (DM) and a leading cause of blindness worldwide. Evidence has shown that DR is an inflammatory disease with hyperglycemia playing a causative role in the development of its main features, including inflammation, cellular apoptosis, neurodegeneration ...
Nikoo, Bayan +2 more
openaire +2 more sources
Advanced Healthcare Materials, EarlyView.This review summarizes the roles of key central nervous system cell types, the extracellular matrix, and the blood‐brain barrier in neuroinflammation, and their integration into diverse 3D culture systems. It examines major incorporation strategies, including direct co‐culture, hydrogel encapsulation, transwell migration assays, and bioprinting ...
Emmanuelle D. Aiyegbusi +2 more
wiley +1 more source
Frontiers in Immunology, 2018 Post viral infection bacterial pneumonia is a major cause of morbidity and mortality associated with both seasonal and pandemic influenza virus illness.
Jaya Talreja +2 more
doaj +1 more source
Molecular alterations of the TLR4-signaling cascade in canine epilepsy
BMC Veterinary Research, 2020 Background Cumulating evidence from rodent models points to a pathophysiological role of inflammatory signaling in the epileptic brain with Toll-like receptor-4 signaling acting as one key factor.
Eva-Lotta von Rüden +8 more
doaj +1 more source
Toll-like receptor-4 signaling pathway in aorta aging and diseases: "its double nature" [PDF]
, 2017 Recent advances in the field of innate immunity have revealed a complex role of innate immune signaling pathways in both tissue homeostasis and disease.
Balistreri, C. +3 more
core +1 more source
Advanced Healthcare Materials, EarlyView.Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim +4 more
wiley +1 more source
Frontiers in ImmunologyIntroductionIn this retrospective study, it was aimed to evaluate effects of Toll Like Receptor 4 (TLR4) and Toll Like Receptor 2 (TLR 2) gene polymorphisms on clinical outcomes in acute non-biliary pancreatitis patients.MethodsA total of 108 acute non ...
Ender Anılır +2 more
doaj +1 more source