Results 51 to 60 of about 219,856 (143)

Activation of Toll-Like Receptor 5 Immune Signaling by HMGB1 [PDF]

Biophysical Journal, 2016
Human High Mobility Group Box-1 (HMGB-1) is an ubiquitously expressed nuclear protein which primarily functions as an architectural chromatin binding factor that binds to DNA in a structure specific manner. Recently, it has been linked to the pathogenesis of several inflammatory diseases regulating the innate immune system by two specific toll-like ...
Das, Nabanita, Dewan, Varun, Hubert Yin, Hang   +2 more
openaire   +1 more source

Effect of Carotenoids, Oligosaccharides and Anthocyanins on Growth Performance, Immunological Parameters and Intestinal Morphology in Broiler Chickens Challenged with Escherichia coli Lipopolysaccharide

Animals, 2020
This study was conducted to investigate the effect of carotenoid, oligosaccharide and anthocyanin supplementation in broiler diets under Escherichia coli lipopolysaccharide (LPS) challenge.
Brigitta Csernus, Sándor Biró, László Babinszky, István Komlósi, András Jávor, László Stündl, Judit Remenyik, Péter Bai, János Oláh, Georgina Pesti-Asbóth, Levente Czeglédi   +10 more
doaj   +1 more source

Helicobacter pyloriInduces Interleukin-8 Secretion by Toll-Like Receptor 2- and Toll-Like Receptor 5-Dependent and -Independent Pathways [PDF]

Infection and Immunity, 2005
ABSTRACTHelicobacter pyloriis an important human pathogen that causes gastritis and is strongly associated with gastric ulcers, gastric adenocarcinomas, and mucosa-associated lymphoid tissue lymphomas. In response toH. pylori, interleukin-8 (IL-8) is secreted from host cells to attract components of the innate and adaptive immune systems to the site of
Anastasia M, Torok, Amy H, Bouton, Joanna B, Goldberg   +2 more
openaire   +2 more sources

Toll‐like receptor 5 in obesity: The role of gut microbiota and adipose tissue inflammation [PDF]

Obesity, 2015
ObjectiveThis study aimed at establishing bacterial flagellin‐recognizing toll‐like receptor 5 (TLR5) as a novel link between gut microbiota composition, adipose tissue inflammation, and obesity.MethodsAn adipose tissue microarray database was used to compare women having the highest (n = 4, H‐TLR) and lowest (n = 4, L‐TLR) expression levels of TLR5 ...
Munukka, Eveliina, Kong, Lingjia, Pöllänen, Eija, Autio, Reija, Roos, Christophe, Wiklund, Petri, Fischer-Posovszky, Pamela, Wabitsch, Martin, Alen, Markku, Huovinen, Pentti, Cheng, Sulin, Pekkala, Satu   +12 more
openaire   +4 more sources

Evaluating the Effects of Cytomegalovirus Glycoprotein B on the Maturation and Function of Monocyte-derived dendritic cells [PDF]

Journal of Advanced Biomedical Sciences, 2015
Background & Objectives: Interaction of cytomegalovirus glycoprotein B with toll-like receptors of dendritic cells leads to early signaling and innate immune responses. The aim of this study is to evaluate the effects of cytomegalovirus glycoprotein B on
Afsson shariat, Ramin Yaghobi, Talat Mokhtariazad, Mohammad Hossein Karimi, Seyed Mohamad Moazeni   +4 more
doaj   +2 more sources

Gene Expression Profiling of Toll-Like Receptor 4 and 5 in Peripheral Blood Mononuclear Cells in Rheumatic Disorders: Ankylosing Spondylitis and Rheumatoid Arthritis

Iranian Journal of Allergy, Asthma and Immunology, 2016
No Abstract###
Simin Almasi, Saeed Aslani, Hadi Poormoghim, Ahmad Reza Jamshidi, Shiva Poursani, Mehdi Mahmoudi   +5 more
doaj  

Kolaviron shows anti-proliferative effect and down regulation of vascular endothelial growth factor-C and toll like receptor-2 in Wuchereria bancrofti infected blood lymphocytes

Journal of Infection and Public Health, 2017
The anti-proliferative effect and down regulation of vascular endothelial growth factor C and toll like receptor-2 by kolaviron on Wuchereria bancrofti infected peripheral blood lymphocytes were investigated.
Aliyu Muhammad, Audu Funmilola, Idowu A. Aimola, Iliya S. Ndams, Mairo H. Inuwa, Andrew J. Nok   +5 more
doaj   +1 more source

Association between polymorphisms in the genes encoding toll-like receptors and dectin-1 and susceptibility to invasive aspergillosis: a systematic review

Revista da Sociedade Brasileira de Medicina Tropical
Invasive aspergillosis is a common fungal infection in immunocompromised individuals. Some studies have shown that toll-like receptor and dectin-1 genetic polymorphisms may alter signaling pathways, thus increasing an individual’s susceptibility to ...
Daiane de Oliveira Cunha, Jacqueline Andréia Bernardes Leão-Cordeiro, Hellen da Silva Cintra de Paula, Fábio Silvestre Ataides, Vera Aparecida Saddi, Cesar Augusto Sam Tiago Vilanova-Costa, Antonio Márcio Teodoro Cordeiro Silva   +6 more
doaj   +1 more source

Toward a porcine in vivo model to analyze the pathogenesis of TLR5-dependent enteropathies

Gut Microbes, 2020
Non-communicable diseases, such as the metabolic syndrome and inflammatory bowel disease, constitute serious public health threats in developed countries.
Robert Pieper, Niels van Best, Kira van Vorst, Friederike Ebner, Monika Reissmann, Mathias W. Hornef, Marcus Fulde   +6 more
doaj   +1 more source

KMRC011, an agonist of toll-like receptor 5, mitigates irradiation-induced tissue damage and mortality in cynomolgus monkeys

Journal of Immunotoxicology, 2020
In the study here, the potential applicability of KMRC011 - an agonist of toll-like receptor-5 – as a countermeasure for radiation toxicities was evaluated.
Hong-Soo Lee, Doo-Wan Cho, Ji-Seok Han, Su-Cheol Han, Sang Keun Woo, Soo-Youn Jun, Woo-Jong Lee, Susie Yoon, Son-Il Pak, Sang-Jin Lee, Eunsol Seong, Eun-Jung Park   +11 more
doaj   +1 more source