Results 41 to 50 of about 219,856 (143)

Stellate ganglion block reduces inflammation and improves neurological function in diabetic rats during ischemic stroke

open access: yesNeural Regeneration Research, 2022
Diabetes mellitus is an independent risk factor for ischemic stroke. Both diabetes mellitus and stroke are linked to systemic inflammation that aggravates patient outcomes.
Ting-Ting Li   +7 more
doaj   +1 more source

Flagellin A Toll-Like Receptor 5 Agonist as an Adjuvant in Chicken Vaccines [PDF]

open access: yesClinical and Vaccine Immunology, 2014
ABSTRACTChicken raised under commercial conditions are vulnerable to environmental exposure to a number of pathogens. Therefore, regular vaccination of the flock is an absolute requirement to prevent the occurrence of infectious diseases. To combat infectious diseases, vaccines require inclusion of effective adjuvants that promote enhanced protection ...
Shishir Kumar, Gupta   +4 more
openaire   +2 more sources

Regulation of Toll-like receptor 5 gene expression and function on mucosal dendritic cells. [PDF]

open access: yesPLoS ONE, 2012
Toll-like receptor (TLR) 5 has been shown to maintain intestinal homeostasis and regulate host defense against enterobacterial infection. However, how TLR5 expression is regulated and its function in the intestine have not been fully elucidated.
Ting Feng   +3 more
doaj   +1 more source

Combination of 5-fluorouracil and Lipopolysaccharide Synergistically Induces Cytotoxicity and Apoptosis in MCF-7 Human Breast Cancer Cells

open access: yesIranian Journal of Allergy, Asthma and Immunology, 2020
Several studies have been conducted to find suitable combinations of drugs to increase the efficacy of chemotherapy and reduce the resistance of tumor cells to treatment.
Negin Nokhandani   +3 more
doaj   +1 more source

The Bacterial Component Flagellin Induces Anti-Sepsis Protection Through TLR-5, IL-1RN and VCAN During Polymicrobial Sepsis in Mice

open access: yesCellular Physiology and Biochemistry, 2015
Background: The present study was designed to observe the effects of the bacterial component flagellin on anti-sepsis protection through TLR-5, VCAN and IL-1RN.
Jiang Zhu   +6 more
doaj   +1 more source

Immunoprotective Effects of Two Histone H2A Variants in the Grass Carp Against Flavobacterium columnare Infection

open access: yesFrontiers in Immunology, 2022
In teleost fish, the nucleotide polymorphisms of histone H2A significantly affect the resistance or susceptibility of zebrafish to Edwardsiella piscicida infection.
Yuan Yuan Yang   +10 more
doaj   +1 more source

A History of Recurrent Positive Selection at the Toll-Like Receptor 5 in Primates [PDF]

open access: yesMolecular Biology and Evolution, 2009
Many genes involved in immunity evolve rapidly. It remains unclear, however, to what extent pattern-recognition receptors (PRRs) of the innate immune system in vertebrates are subject to recurrent positive selection imposed by pathogens, as suggested by studies in Drosophila, or whether they are evolutionarily constrained.
Gabriela, Wlasiuk   +3 more
openaire   +2 more sources

The Toll-Like Receptor 5 Agonist Entolimod Mitigates Lethal Acute Radiation Syndrome in Non-Human Primates. [PDF]

open access: yesPLoS ONE, 2015
There are currently no approved medical radiation countermeasures (MRC) to reduce the lethality of high-dose total body ionizing irradiation expected in nuclear emergencies.
Vadim I Krivokrysenko   +13 more
doaj   +1 more source

Toll-Like Receptors 4 and 5 Induce Distinct Types of Vasculitis [PDF]

open access: yesCirculation Research, 2009
Large vessel vasculitides, such as Takayasu arteritis and giant cell arteritis, affect vital arteries and cause clinical complications by either luminal occlusion or vessel wall destruction. Inflammatory infiltrates, often with granulomatous arrangements, are distributed as a panarteritis throughout all of the artery’s wall layers or ...
Jiusheng, Deng   +5 more
openaire   +2 more sources

How Flagellin and Toll-Like Receptor 5 Contribute to Enteric Infection [PDF]

open access: yesInfection and Immunity, 2007
Resistance to infection in vertebrates relies on a complex interaction between two separate but complementary arms of the immune system: adaptive immunity and innate immunity. Adaptive immunity refers to the recognition of specific molecular epitopes by either T or B lymphocytes and the ...
openaire   +2 more sources

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