Results 31 to 40 of about 219,856 (143)
Frontiers in Veterinary Science, 2021 Background: Whether the probiotic Clostridium butyricum (CB) alleviates enterotoxigenic Escherichia coli (ETEC) K88-induced inflammation by regulating the activation of the toll-like receptor (TLR) signaling pathway is not clear, thus, we carried out ...
Haihua Li +3 more
doaj +1 more source
Journal of Infection in Developing Countries, 2022 Introduction: Tuberculosis has been a concern of healthcare professionals due to the serious threats it poses on public health safety. However, regardless all the efforts, no appropriate goals for immunological diagnosis or tuberculosis treatment were ...
Eman A El-Masry +3 more
doaj +1 more source
Involvement of Toll-like receptor 5 in the recognition of flagellated bacteria [PDF]
Proceedings of the National Academy of Sciences, 2006 Toll-like receptors (TLRs) are key components of the immune system that detect microbial infection and trigger antimicrobial host defense responses. TLR5 is a sensor for monomeric flagellin, which is a component of bacterial flagella known to be a virulence factor. In this study we generated TLR5-deficient mice and investigated the
Feuillet, Vincent +7 more
openaire +3 more sources
Pattern-recognition receptors in endometriosis: A narrative review
Frontiers in Immunology, 2023 Endometriosis is closely associated with ectopic focal inflammation and immunosuppressive microenvironment. Multiple types of pattern recognition receptors (PRRs) are present in the innate immune system, which are able to detect pathogen-associated ...
Bao Guo +7 more
doaj +1 more source
Structural Study of Binding of Flagellin by Toll-Like Receptor 5 [PDF]
Journal of Bacteriology, 2003 ABSTRACTIn order to predict the binding regions within the complex formed by Toll-like receptor 5 (TLR-5) and flagellin, a complementary hydropathy between the two proteins was sought. A region common to the flagellins ofSalmonella entericaserovar Typhimurium,Pseudomonas aeruginosa, andListeria monocytogeneswas shown to be hydropathically complementary
Saul G, Jacchieri +2 more
openaire +2 more sources
Toll-like receptor 5 and the emerging role of bacteria in carcinogenesis [PDF]
OncoImmunology, 2013 Toll-like receptor 5 (TLR5) is an pattern recognition receptor expressed by several cells of the immune system that recognizes bacterial flagellin. We studied the influence of TLR5 in oral tongue squamous carcinoma and found that its expression levels predict patient survival and recurrence.
Salo Tuula +3 more
openaire +2 more sources
Roseburia intestinalis stimulates TLR5-dependent intestinal immunity against Crohn's disease
EBioMedicine, 2022 Summary: Background: Crohn's disease (CD) is a chronic inflammatory disorder characterized by intestinal immune dysfunction. Multiple factors, including gut dysbiosis, are involved in the pathogenesis of CD.
Zhaohua Shen +14 more
doaj +1 more source
Infection-induced 5'-half molecules of tRNAHisGUG activate Toll-like receptor 7.
PLoS Biology, 2020 Toll-like receptors (TLRs) play a crucial role in the innate immune response. Although endosomal TLR7 recognizes single-stranded RNAs, their endogenous RNA ligands have not been fully explored.
Kamlesh Pawar +3 more
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Journal of Biomedical Science, 2021 Background Toll-like receptor-2 (TLR2) promotes vascular smooth muscle cell (VSMC) transdifferentiation to chondrocytes and calcification in a p38 MAPK-dependent manner.
Guan-Lin Lee +4 more
doaj +1 more source
A flagellin-derived toll-like receptor 5 agonist stimulates cytotoxic lymphocyte-mediated tumor immunity. [PDF]
PLoS ONE, 2014 Toll-like receptor (TLR) mediated recognition of pathogen associated molecular patterns allows the immune system to rapidly respond to a pathogenic insult.
Nicholas D Leigh +7 more
doaj +1 more source