Results 1 to 10 of about 1,183 (69)
Gut Microbes, 2023 Intestinal contents comprise the largest repository of immunogenic ligands of microbial origin. We undertook this study to assess the predominant microbe-associated molecular patterns (MAMPs) present therein and the receptors) that mediate the innate ...
Matam Vijay-Kumar +6 more
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Role of Toll-Like Receptor 5 in the Development of Ulcerative Colitis [PDF]
Archives of Razi Institute, 2021 Inflammatory bowel disease (ulcerative colitis and Crohn’s disease) is a remitting and relapsing disease that affects millions of people worldwide. In the intestine, homeostasis between repair and signaling of the proinflammatory of the immune system is ...
A Falah Alshimerry +2 more
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Toll-like receptor 5 tunes hepatic and pancreatic stellate cells activation
BMJ Open Gastroenterology, 2023 Objective Stellate cells are responsible for liver and pancreas fibrosis and strictly correlate with tumourigenesis. Although their activation is reversible, an exacerbated signalling triggers chronic fibrosis.
Malte Buchholz +6 more
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Determinants of Divergent Adaptive Immune Responses after Airway Sensitization with Ligands of Toll-Like Receptor 5 or Toll-Like Receptor 9. [PDF]
PLoS ONE, 2016 Excessive type 2 helper T cell responses to environmental antigens can cause immunopathology such as asthma and allergy, but how such immune responses are induced remains unclear.
Linda M Lee +9 more
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3-(5-Hydroxyphenyl)-5-Phenyl-2-Pyrazolines as Toll-Like Receptor 7 Agonists
Journal of Chemistry, 2023 Toll-like receptor 7 (TLR7) is an attractive target for developing immune modulators to enhance innate immunity against ssRNA virus infections, including hepatitis C and COVID-19.
Ji Hwan Kim +5 more
doaj +1 more source
Toll-like receptor 5-mediated signaling enhances liver regeneration in mice
Military Medical Research, 2021 Background Toll-like receptor 5 (TLR5)-mediated pathways play critical roles in regulating the hepatic immune response and show hepatoprotective effects in mouse models of hepatic diseases.
Wen Zhang +14 more
doaj +1 more source
The role of the C-terminal D0 domain of flagellin in activation of Toll like receptor 5. [PDF]
PLoS Pathogens, 2017 Flagellin is a wide-spread bacterial virulence factor sensed by the membrane-bound Toll-like receptor 5 (TLR5) and by the intracellular NAIP5/NLRC4 inflammasome receptor.
Vida Forstnerič +4 more
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miR‐155‐regulated mTOR and Toll‐like receptor 5 in gastric diffuse large B‐cell lymphoma
Cancer Medicine, 2022 Background Gastric diffuse large B‐cell lymphoma (DLBCL) is often associated with Helicobacter pylori (H. pylori) infection. Those in the early stage could be treated with H.
Wei‐Ting Huang +3 more
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Egyptian Rheumatology and Rehabilitation, 2021 Background Toll-like (TLRs) play a crucial role in both adaptive and innate immunity. The aim of the present study was to assess the association of TLR5-rs5744168, TLR9-rs187084, and TLR9-rs352140 single nucleotide polymorphisms (SNPs) with ...
Ola Mohammad Gharbia +6 more
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Frontiers in Veterinary Science, 2022 This study aimed to evaluate the clinical safety and validate the radiomitigative effect of KMRC011, against radiation-induced oral mucositis in beagle dogs.
Jaeeun Ko +9 more
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