Results 41 to 50 of about 219,955 (241)
Toll-like receptor 5 as a novel receptor for fungal zymosan [PDF]
, 2021 Microbial pathogens carry specific structural patterns which were termed pathogen-associated molecular patterns (PAMPs). Toll-like receptors (TLRs) as key elements for the recognition of microbial pathogens are necessary for the activation of innate immune pathways.
Stefanie Reuter +3 more
openaire +1 more source
A flagellin-derived toll-like receptor 5 agonist stimulates cytotoxic lymphocyte-mediated tumor immunity. [PDF]
PLoS ONE, 2014 Toll-like receptor (TLR) mediated recognition of pathogen associated molecular patterns allows the immune system to rapidly respond to a pathogenic insult.
Nicholas D Leigh +7 more
doaj +1 more source
Neural Regeneration Research, 2022 Diabetes mellitus is an independent risk factor for ischemic stroke. Both diabetes mellitus and stroke are linked to systemic inflammation that aggravates patient outcomes.
Ting-Ting Li +7 more
doaj +1 more source
Regulation of Toll-like receptor 5 gene expression and function on mucosal dendritic cells. [PDF]
PLoS ONE, 2012 Toll-like receptor (TLR) 5 has been shown to maintain intestinal homeostasis and regulate host defense against enterobacterial infection. However, how TLR5 expression is regulated and its function in the intestine have not been fully elucidated.
Ting Feng +3 more
doaj +1 more source
Iranian Journal of Allergy, Asthma and Immunology, 2020 Several studies have been conducted to find suitable combinations of drugs to increase the efficacy of chemotherapy and reduce the resistance of tumor cells to treatment.
Negin Nokhandani +3 more
doaj +1 more source
A History of Recurrent Positive Selection at the Toll-Like Receptor 5 in Primates [PDF]
Molecular Biology and Evolution, 2009 Many genes involved in immunity evolve rapidly. It remains unclear, however, to what extent pattern-recognition receptors (PRRs) of the innate immune system in vertebrates are subject to recurrent positive selection imposed by pathogens, as suggested by studies in Drosophila, or whether they are evolutionarily constrained.
Gabriela, Wlasiuk +3 more
openaire +2 more sources
Cellular Physiology and Biochemistry, 2015 Background: The present study was designed to observe the effects of the bacterial component flagellin on anti-sepsis protection through TLR-5, VCAN and IL-1RN.
Jiang Zhu +6 more
doaj +1 more source
Frontiers in Immunology, 2022 In teleost fish, the nucleotide polymorphisms of histone H2A significantly affect the resistance or susceptibility of zebrafish to Edwardsiella piscicida infection.
Yuan Yuan Yang +10 more
doaj +1 more source
Determining Parental Factors for Clinical Trial Attrition in Pediatric Acute Lymphoblastic Leukemia
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background/Objectives Despite high enrollment rates on Children's Oncology Group (COG) protocols, attrition after initial consent is challenging, introducing bias and prolonging trial completion. While adult oncology literature has identified predictors of withdrawal, little is known about caregiver decision‐making for child participation in ...
Kimberly L. Stathas +3 more
wiley +1 more source
Activation of Toll-Like Receptor 5 Immune Signaling by HMGB1 [PDF]
Biophysical Journal, 2016 Human High Mobility Group Box-1 (HMGB-1) is an ubiquitously expressed nuclear protein which primarily functions as an architectural chromatin binding factor that binds to DNA in a structure specific manner. Recently, it has been linked to the pathogenesis of several inflammatory diseases regulating the innate immune system by two specific toll-like ...
Das, Nabanita +2 more
openaire +1 more source