Results 41 to 50 of about 348,116 (277)
Journal of Innate Immunity, 2021 Eosinophil (Eo) degranulation plays a central role in the initiations of allergic attacks. Flagellin (FGN), the major component of bacterial flagella, has immune regulatory functions.
Xiang-Qian Luo +7 more
doaj +1 more source
Structural Study of Binding of Flagellin by Toll-Like Receptor 5 [PDF]
Journal of Bacteriology, 2003 ABSTRACTIn order to predict the binding regions within the complex formed by Toll-like receptor 5 (TLR-5) and flagellin, a complementary hydropathy between the two proteins was sought. A region common to the flagellins ofSalmonella entericaserovar Typhimurium,Pseudomonas aeruginosa, andListeria monocytogeneswas shown to be hydropathically complementary
Saul G, Jacchieri +2 more
openaire +2 more sources
Frontiers in Veterinary Science, 2021 Background: Whether the probiotic Clostridium butyricum (CB) alleviates enterotoxigenic Escherichia coli (ETEC) K88-induced inflammation by regulating the activation of the toll-like receptor (TLR) signaling pathway is not clear, thus, we carried out ...
Haihua Li +3 more
doaj +1 more source
Toll-like receptor 5 and the emerging role of bacteria in carcinogenesis [PDF]
OncoImmunology, 2013 Toll-like receptor 5 (TLR5) is an pattern recognition receptor expressed by several cells of the immune system that recognizes bacterial flagellin. We studied the influence of TLR5 in oral tongue squamous carcinoma and found that its expression levels predict patient survival and recurrence.
Salo Tuula +3 more
openaire +2 more sources
Journal of Infection in Developing Countries, 2022 Introduction: Tuberculosis has been a concern of healthcare professionals due to the serious threats it poses on public health safety. However, regardless all the efforts, no appropriate goals for immunological diagnosis or tuberculosis treatment were ...
Eman A El-Masry +3 more
doaj +1 more source
Pattern-recognition receptors in endometriosis: A narrative review
Frontiers in Immunology, 2023 Endometriosis is closely associated with ectopic focal inflammation and immunosuppressive microenvironment. Multiple types of pattern recognition receptors (PRRs) are present in the innate immune system, which are able to detect pathogen-associated ...
Bao Guo +7 more
doaj +1 more source
Structural modification of the antidepressant mianserin suggests that its anti-inflammatory activity may be independent of 5-Hydroxytryptamine receptors [PDF]
, 2019 Antidepressants are increasingly recognized to have anti-inflammatory properties in addition to their ability to treat major depressive disorders. To explore if engagement of 5-hydroxytryptamine (5-HT) receptors was required for the anti-inflammatory ...
Chamberlain, Giselle +4 more
core +4 more sources
Contemporary views on inflammatory pain mechanisms: TRPing over innate and microglial pathways. [PDF]
, 2016 Tissue injury, whether by trauma, surgical intervention, metabolic dysfunction, ischemia, or infection, evokes a complex cellular response (inflammation) that is associated with painful hyperalgesic states.
Guan, Zhonghui +2 more
core +2 more sources
Flagellin A Toll-Like Receptor 5 Agonist as an Adjuvant in Chicken Vaccines [PDF]
Clinical and Vaccine Immunology, 2014 ABSTRACTChicken raised under commercial conditions are vulnerable to environmental exposure to a number of pathogens. Therefore, regular vaccination of the flock is an absolute requirement to prevent the occurrence of infectious diseases. To combat infectious diseases, vaccines require inclusion of effective adjuvants that promote enhanced protection ...
Shishir Kumar, Gupta +4 more
openaire +2 more sources
Toll-like receptor 5 as a novel receptor for fungal zymosan [PDF]
, 2021 Microbial pathogens carry specific structural patterns which were termed pathogen-associated molecular patterns (PAMPs). Toll-like receptors (TLRs) as key elements for the recognition of microbial pathogens are necessary for the activation of innate immune pathways.
Stefanie Reuter +3 more
openaire +1 more source