Results 41 to 50 of about 16,611,336 (253)
Modulation of Toll-like receptor activity by leukocyte Ig-like receptors and their effects during bacterial infection. [PDF]
, 2010 Toll-like receptors (TLRs) are a potent trigger for inflammatory immune responses. Without tight regulation their activation could lead to pathology, so it is imperative to extend our understanding of the regulatory mechanisms that govern TLR expression ...
Martin Vordermeier +5 more
core +1 more source
Flagellin A Toll-Like Receptor 5 Agonist as an Adjuvant in Chicken Vaccines [PDF]
Clinical and Vaccine Immunology, 2014 ABSTRACTChicken raised under commercial conditions are vulnerable to environmental exposure to a number of pathogens. Therefore, regular vaccination of the flock is an absolute requirement to prevent the occurrence of infectious diseases. To combat infectious diseases, vaccines require inclusion of effective adjuvants that promote enhanced protection ...
Shishir Kumar, Gupta +4 more
openaire +2 more sources
A flagellin-derived toll-like receptor 5 agonist stimulates cytotoxic lymphocyte-mediated tumor immunity. [PDF]
PLoS ONE, 2014 Toll-like receptor (TLR) mediated recognition of pathogen associated molecular patterns allows the immune system to rapidly respond to a pathogenic insult.
Nicholas D Leigh +7 more
doaj +1 more source
Neural Regeneration Research, 2022 Diabetes mellitus is an independent risk factor for ischemic stroke. Both diabetes mellitus and stroke are linked to systemic inflammation that aggravates patient outcomes.
Ting-Ting Li +7 more
doaj +1 more source
Regulation of Toll-like receptor 5 gene expression and function on mucosal dendritic cells. [PDF]
PLoS ONE, 2012 Toll-like receptor (TLR) 5 has been shown to maintain intestinal homeostasis and regulate host defense against enterobacterial infection. However, how TLR5 expression is regulated and its function in the intestine have not been fully elucidated.
Ting Feng +3 more
doaj +1 more source
Cellular Physiology and Biochemistry, 2015 Background: The present study was designed to observe the effects of the bacterial component flagellin on anti-sepsis protection through TLR-5, VCAN and IL-1RN.
Jiang Zhu +6 more
doaj +1 more source
Iranian Journal of Allergy, Asthma and Immunology, 2020 Several studies have been conducted to find suitable combinations of drugs to increase the efficacy of chemotherapy and reduce the resistance of tumor cells to treatment.
Negin Nokhandani +3 more
doaj +1 more source
The expression of Toll-like receptor 5 in preterm histologic chorioamnionitis
Journal of Clinical Biochemistry and Nutrition, 2018 Spontaneous preterm birth is often caused by chorioamnionitis. Toll-like receptors (TLRs) have a role in the response of the innate immune system. The role of TLR5 in chorioamnionitis remains unclear: however, TLR5 was reported to have a significantly stronger effect on the induction of interleukin (IL)-6 when compared with other TLRs in amniotic ...
Moroi, Hiroaki +13 more
openaire +3 more sources
A History of Recurrent Positive Selection at the Toll-Like Receptor 5 in Primates [PDF]
Molecular Biology and Evolution, 2009 Many genes involved in immunity evolve rapidly. It remains unclear, however, to what extent pattern-recognition receptors (PRRs) of the innate immune system in vertebrates are subject to recurrent positive selection imposed by pathogens, as suggested by studies in Drosophila, or whether they are evolutionarily constrained.
Gabriela, Wlasiuk +3 more
openaire +2 more sources
Fibronectin III 13-14 Domains Induce Joint Damage via Toll-Like Receptor 4 Activation and Synergize with Interleukin-1 and Tumour Necrosis Factor [PDF]
, 2011 Cartilage loss is a feature of chronic arthritis. It results from degradation of the extracellular matrix which is composed predominantly of aggrecan and type II collagen.
Saralili Dipa Robertson +6 more
core +1 more source