Results 51 to 60 of about 348,116 (277)
A History of Recurrent Positive Selection at the Toll-Like Receptor 5 in Primates [PDF]
Molecular Biology and Evolution, 2009 Many genes involved in immunity evolve rapidly. It remains unclear, however, to what extent pattern-recognition receptors (PRRs) of the innate immune system in vertebrates are subject to recurrent positive selection imposed by pathogens, as suggested by studies in Drosophila, or whether they are evolutionarily constrained.
Gabriela, Wlasiuk +3 more
openaire +2 more sources
A flagellin-derived toll-like receptor 5 agonist stimulates cytotoxic lymphocyte-mediated tumor immunity. [PDF]
PLoS ONE, 2014 Toll-like receptor (TLR) mediated recognition of pathogen associated molecular patterns allows the immune system to rapidly respond to a pathogenic insult.
Nicholas D Leigh +7 more
doaj +1 more source
Neural Regeneration Research, 2022 Diabetes mellitus is an independent risk factor for ischemic stroke. Both diabetes mellitus and stroke are linked to systemic inflammation that aggravates patient outcomes.
Ting-Ting Li +7 more
doaj +1 more source
Regulation of Toll-like receptor 5 gene expression and function on mucosal dendritic cells. [PDF]
PLoS ONE, 2012 Toll-like receptor (TLR) 5 has been shown to maintain intestinal homeostasis and regulate host defense against enterobacterial infection. However, how TLR5 expression is regulated and its function in the intestine have not been fully elucidated.
Ting Feng +3 more
doaj +1 more source
LRR-containing receptors regulating plant development and defense [PDF]
, 2004 Despite the presence of more than 400 genes that encode receptor-like kinases (RLKs) in the Arabidopsis thaliana genome, very little is known about the range of biological processes that they control, or the mechanisms by which they function. This review
Clark, Steven E., Dievart, Anne
core +1 more source
Activation of Toll-Like Receptor 5 Immune Signaling by HMGB1 [PDF]
Biophysical Journal, 2016 Human High Mobility Group Box-1 (HMGB-1) is an ubiquitously expressed nuclear protein which primarily functions as an architectural chromatin binding factor that binds to DNA in a structure specific manner. Recently, it has been linked to the pathogenesis of several inflammatory diseases regulating the innate immune system by two specific toll-like ...
Das, Nabanita +2 more
openaire +1 more source
Iranian Journal of Allergy, Asthma and Immunology, 2020 Several studies have been conducted to find suitable combinations of drugs to increase the efficacy of chemotherapy and reduce the resistance of tumor cells to treatment.
Negin Nokhandani +3 more
doaj +1 more source
Toll-like receptor-mediated signaling cascade as a regulator of the inflammation network during alcoholic liver disease [PDF]
, 2014 Chronic abuse of alcohol leads to various histological abnormalities in the liver. These are conditions collectively known as alcoholic liver disease (ALD). Currently, ALD is considered to be one of the major causes of death worldwide.
Alisi, A., Ceccarelli, S, Nobili, V
core +1 more source
Chicken Toll-like Receptor 3 Recognizes Its Cognate Ligand When Ectopically Expressed in Human Cells [PDF]
, 2007 Recognition of pathogens by toll-like receptors (TLRs) causes activation of signaling cascades that trigger cytokine secretion and, ultimately, innate immunity.
Bauer, Stefan +7 more
core +1 more source
Cellular Physiology and Biochemistry, 2015 Background: The present study was designed to observe the effects of the bacterial component flagellin on anti-sepsis protection through TLR-5, VCAN and IL-1RN.
Jiang Zhu +6 more
doaj +1 more source