Results 141 to 150 of about 608,641 (362)
Медицинская иммунология, 2015 Expression of Toll-like receptors (TLRs) on myeloid cells is of key importance for induction of systemic reactions caused by bacterial damage, and activation mechanisms of innate immune response. The study included thirty-six patients with sepsis in whom
V. A. Lazanovich +3 more
doaj +1 more source
Advanced Materials, EarlyView.A reprogrammed (RP) phage‐based nanovaccine platform has been developed that allows single‐step assembly with precise control over adjuvanticity, antigen density, and nanoparticle size. By enhancing TLR9 activation and neoantigen display, this platform enables a potent personalized vaccine targeting tumor‐specific neoantigens. When combined with immune
Shengnan Huang +10 more
wiley +1 more source
The apoptotic signaling pathway activated by Toll-like receptor-2 [PDF]
, 2000 Antonios O. Aliprantis
openalex +1 more source
Toll-like Receptors and the Control of Immunity
Cell, 2020 K. Fitzgerald, Jonathan C. Kagan
semanticscholar +1 more source
Novel mutations in the toll like receptor genes cause hyporesponsiveness to Mycobacterium avium subsp. paratuberculosis infection [PDF]
, 2008 Toll like receptors play a central role in the recognition of pathogen associated molecular patterns (PAMPs). Mutations in TLR1, TLR2 and TLR4 genes may change the PAMP reorganization ability which causes altered responsiveness to the bacterial pathogens.
Ivan Mikula Jr. +6 more
core +1 more source
Advanced Materials Interfaces, EarlyView.This study confirms that extracellular vesicles (EVs) derived from mesenchymal stem cells (MSCs) or HEK293F cells overexpressing CD24 have anti‐inflammatory effects in macrophages and monocytes. Further loading either of these EVs with an anti‐Myd88 peptide synergistically enhanced the anti‐inflammatory effects of the EVs.
Burçin İrem Abas +6 more
wiley +1 more source
Maturation of Human Dendritic Cells by Cell Wall Skeleton ofMycobacterium bovisBacillus Calmette-Guérin: Involvement of Toll-Like Receptors [PDF]
, 2000 Shoutaro Tsuji +7 more
openalex +1 more source
Advanced Science, EarlyView.Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian +26 more
wiley +1 more source
Cutting Edge: Heat Shock Protein 60 Is a Putative Endogenous Ligand of the Toll-Like Receptor-4 Complex [PDF]
, 2000 Koji Ohashi +3 more
openalex +1 more source
The implication of dendritic cells in lung diseases: Immunological role of toll-like receptor 4
Genes and DiseasesThe immune responses play a profound role in the progression of lung lesions in both infectious and non-infectious diseases. Dendritic cells, as the “frontline” immune cells responsible for antigen presentation, set up a bridge between innate and ...
Shurui Xuan +5 more
doaj +1 more source