Results 61 to 70 of about 303,288 (302)

TLR9-based immunotherapy for the treatment of allergic diseases [PDF]

, 2017
Toll-like receptors (TLRs), a family of pattern recognition receptors expressed on many cell types of innate immunity, recognize the pathogen-associated molecular patterns of microbes.
Akira S, Ali Movahed, Farrokhi S, Hoshino K, Hossein Ali Khazaei, Kline JN, Masoud Pishjoo, Narjes Abbasirad, Nima Rezaei, Shokrollah Farrokhi, Spiegelberg HL, Sur S   +11 more
core   +1 more source

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers, Yueh‐Yun Lin, Jason R. Thonhoff, Aaron D. Thome, Alireza Faridar, Weihua Zhao, Shixiang Wen, Stanley H. Appel   +7 more
wiley   +1 more source

Expression of Toll-like receptors 3, 7, and 9 in peripheral blood mononuclear cells and prognosis of pneumonia in hospital-admitted coronavirus disease 2019 patients: is there an association?

Egyptian Journal of Chest Disease and Tuberculosis
Background Toll-like receptors (TLRs) identify the very early signs of cell damage or infection. They play essential roles in host immunity response against severe acute respiratory syndrome coronavirus 2 infection.
Gamal Agmy, Fady Khalifa, Mohamed Adam, Mohamed Mokhtar, Manal A. Mahmoud   +4 more
doaj   +1 more source

Modulation of pathogen recognition by autophagy

Frontiers in Immunology, 2012
Autophagy is an ancient biological process for maintaining cellular homeostasis by degradation of long-lived cytosolic proteins and organelles. Recent studies demonstrated that autophagy is availed by immune cells to regulate innate immunity.
Ji Eun eOh, Heung Kyu eLee
doaj   +1 more source

COVID‐19 Vaccination Is Not Associated With the Development of Idiopathic Inflammatory Myositis in US Veterans

Arthritis Care &Research, EarlyView.
Objective Several case reports have proposed a potential association between COVID‐19 vaccination and the subsequent development of idiopathic inflammatory myositis (IIM). This study examined prior COVID‐19 vaccination in US veterans who developed new‐onset IIM compared to those without new‐onset IIM.
Caleb Hernández, Naomi Schlesinger, Jorge Rojas, Jessica A. Walsh, Tawnie J. Braaten, Gary A. Kunkel, Makoto Jones, Brian C Sauer, Julio Facelli, Grant W. Cannon, Dorota Lebiedz‐Odrobina   +10 more
wiley   +1 more source

Role of toll-like receptors and nod-like receptors in acute lung infection

Frontiers in Immunology, 2023
The respiratory system exposed to microorganisms continuously, and the pathogenicity of these microbes not only contingent on their virulence factors, but also the host’s immunity. A multifaceted innate immune mechanism exists in the respiratory tract to
John Le, Yathushigan Kulatheepan, Samithamby Jeyaseelan, Samithamby Jeyaseelan   +3 more
doaj   +1 more source

Toll-Like Receptors and Cancer: MYD88 Mutation and Inflammation

, 2016
Pattern recognition receptors (PRRs) expressed on immune cells are crucial for the early detection of invading pathogens, in initiating early innate immune response and in orchestrating the adaptive immune response.
Ferguson, Laura L., Horikawa, Keisuke, Jeelall, Yogesh S., Wang, James Q.   +3 more
core   +1 more source

Artificial Intelligence–Based Online Symptom Assessment Tools for Systemic Lupus Erythematosus Diagnosis: Patient Perspectives

Arthritis Care &Research, EarlyView.
Objective The objective of this article is to identify perceptions of patients with systemic lupus erythematosus (SLE) regarding artificial intelligence (AI)–based online symptom assessment tools, and the potential of these tools to address diagnostic barriers.
Olivia A. Stein, Jennifer L. F. Lee, Evelyne Vinet, Arielle Mendel, Christian A. Pineau, Fares Kalache, Louis‐Pierre Grenier, Sasha Bernatsky   +7 more
wiley   +1 more source

Immunity, Inflammation and Heart Failure: Their Role on Cardiac Function and Iron Status [PDF]

, 2019
Aims: Heart failure is a clinical syndrome characterized by subclinical systemic inflammation and immune system activation associated with iron deficiency.
Corrao S., Gigliotti S., Greco M., Hribal M. L., Miceli S., Perticone F., Perticone M., Pinto A., Sesti G., Suraci E., Zito R.   +10 more
core   +1 more source

Intracellular Toll-like Receptors [PDF]

Immunity, 2010
Foreign nucleic acids, the signature of invading viruses and certain bacteria, are sensed intracellularly. The nucleic acid-specific Toll-like receptors (TLRs) detect and signal within endolysosomal compartments, triggering the induction of cytokines essential for the innate immune response.
Blasius, Amanda L., Beutler, Bruce
openaire   +2 more sources