Results 141 to 150 of about 5,833,753 (257)

Cryo-EM structure of the mitochondrial protein-import channel TOM complex at near-atomic resolution. [PDF]

Nat Struct Mol Biol, 2019
Tucker K, Park E.
europepmc   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Tom Roberts' autograph book [picture].

, 1883
Includes drawings by Tom Roberts and others, e.g. Phil May and Girolamo Nerli.; First two pages have inscriptions and notes by Tom Roberts.; Also available online at: http://nla.gov.au/nla.pic-an5714550; R8802 ...
Roberts, Tom, 1856-1931.
core  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Evolution and Adaptation of the Mitochondrial Protein Import Machinery in Parasitic Protists: Beyond the Canonical TOM Complex. [PDF]

Int J Mol Sci
Anvari E, Daryabor G, Sedigh A, Rashidi S, Nguewa P.   +4 more
europepmc   +1 more source

Cable and Wireless Relay Station, Direction Island, Cocos Islands between 1952 and 1954 [picture] /

, 1952
Title from acquisition documentation.; This photograph is in private ownership.; Part of the collection: Photographs from Tom Meigan's Cocos (Keeling) Islands albums, 1952-1954.; Electronic reproduction. Canberra : National Library of Australia, 2004. 1
Meigan, Tom, 1931-
core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

A dynamic gateway: Uncovering the expanded human TOM complex interactome and its regulatory complexity. [PDF]

Sci Adv
Borrero-Landazabal MA, Linke V, Kadavá T, Li Z, Draczkowski P, Kaszuba K, Bertgen L, Serwa RA, Heck AJR, Chacinska A.   +9 more
europepmc   +1 more source

Avro York from the American Embassy in Singapore refuelling on West Island, Cocos Islands between 1952 and 1954 [picture] /

, 1952
Title from acquisition documentation.; This photograph is in private ownership.; Part of the collection: Photographs from Tom Meigan's Cocos (Keeling) Islands albums, 1952-1954.; Electronic reproduction. Canberra : National Library of Australia, 2004. 1
Meigan, Tom, 1931-
core  

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source