Results 211 to 220 of about 54,149 (242)

Tonic cholinergic inhibition of spinal mechanical transmission

Pain, 1991
The present study examined the role of spinal cholinergic modulation of spinal mechanical and thermal transmission. Intrathecal administration of the cholinergic muscarinic receptor antagonists atropine or scopolamine in awake rats produced a dose-dependent decrease in the nociceptive mechanical withdrawal threshold of the rat tail.
M, Zhuo, G F, Gebhart
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Tonically Balancing Intracortical Excitation and Inhibition by GABAergic Gliotransmission

Neural Computation, 2014
For sensory cortices to respond reliably to feature stimuli, the balancing of neuronal excitation and inhibition is crucial. A typical example might be the balancing of phasic excitation within cell assemblies and phasic inhibition between cell assemblies. The former controls the gain of and the latter the tuning of neuronal responses.
Mei Hong Zheng, Takami Matsuo, Ai Miyamoto, Osamu Hoshino   +3 more
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Barium inhibition of the tonic component of frog atrial contraction

Pfl�gers Archiv European Journal of Physiology, 1985
Barium ions are able to substitute for calcium as charge carriers for the slow inward current of cardiac membrane. The effects of such a substitution on the mechanical activity of voltage-clamped frog atrial trabeculae have been investigated using the double mannitol gap device coupled with a mechano-electric transducer. In the presence of barium, the '
D, Potreau, G, Raymond
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Tonic in vivo inhibition of rabbit myometrial adrenergic receptors

Nature, 1981
With the development of radioligand binding assays for identifying hormone receptors directly, it has become evident that the number of receptors in a particular cell or tissue does not remain constant but can in fact, be regulated by a variety of agents1.
L E, Cornett, A, Goldfien, J M, Roberts
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Tonic opioid inhibition of the subiculo‐accumbens pathway

Synapse, 2001
AbstractThere is evidence to suggest that medium spiny neurons (MSNs) in the nucleus accumbens (NAS) should be sensitive to opiate compounds. However, neuronal responses in the NAS evoked by fimbria stimulation (F‐D) are insensitive to systemically or iontophoretically administered morphine.
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Tonic inhibition of small intestinal motility by nitric oxide

Journal of the Autonomic Nervous System, 1993
The effects of blocking nitric oxide synthase with the arginine analog N omega-nitro-L-arginine (L-NNA) were investigated in anaesthetized cats, vagotomized and pretreated with guanethidine and atropine. Spontaneous NANC jejunal motility (recorded as the volume changes of an intraluminal balloon) was markedly increased in a dose-dependent and ...
B I, Gustafsson, D S, Delbro
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Substrate-Selective Inhibition of Mitochondrial Oxidations by Enhanced Tonicity

Nature, 1958
DURING an investigation of factors controlling rates of oxidation by mitochondria, it was found that variations of sucrose concentration in the suspending medium profoundly inhibited the oxygen consumption with some substrates but had much less effect with others.
D, JOHNSON, H, LARDY
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Tonic inhibition of thermoregulation in the decerebrate monkey (Saimiri sciureus)

Experimental Neurology, 1979
Abstract In monkeys ( Saimiri sciureus ) acute truncation of the brain stem just caudal to the hypothalamus or rostral to the pons results in a preparation which rapidly loses body heat without shivering, piloerection, and vasoconstriction of cutaneous vessles.
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Tonic inhibition by orphanin FQ/nociceptin of noradrenaline neurotransmission in the amygdala

European Journal of Pharmacology, 2004
The present microdialysis study investigated whether nociceptin/orphanin FQ exerts a tonic inhibition of the release of noradrenaline in the basolateral nucleus of the amygdala in awake rats. The non-peptide competitive nociceptin/orphanin FQ (N/OFQ) peptide receptor antagonist J-113397 (20 mg/kg i.p.) induced an increase in the release of ...
Kawahara, Y, Hesselink, M.B., van Scharrenburg, G, Westerink, B.H.C.   +3 more
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Somatostatin tonically inhibits growth hormone secretion in domestic fowl

Journal of Endocrinology, 1986
ABSTRACT Passive immunization of immature chickens with sheep somatostatin (SRIF) antiserum promptly increased the basal plasma GH concentration and augmented TRH-induced GH secretion. Although exogenous SRIF had no inhibitory effect on the basal GH concentration in untreated birds or birds pretreated with non-immune sheep serum, it suppressed ...
S, Harvey, S K, Lam, T R, Hall
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