Results 51 to 60 of about 209,354 (197)

Dermatologic Toxicities Associated With Novel Pan‐RAS/RAF Inhibitors

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Background The mitogen‐activated protein kinase (MAPK) pathway plays a key role in cell‐cycle regulation and tumor progression in cancer. Dermatologic toxicities (DTs) to newer pan‐RAS (RMC‐6236) and pan‐RAF (LXH254/naporafenib) inhibitors are emerging.
Lin J. He, Shaymaa Hegazy, Phyu P. Aung, Priyadharsini Nagarajan, Fiorinda Muhaj, Adrienne N. Choksi, Ana M. Ciurea, Kelly C. Nelson, Doina Ivan, Carlos A. Torres‐ Cabala, Victor G. Prieto, Jonathan L. Curry   +11 more
wiley   +1 more source

Acne Vulgaris Management: A Review of First-Line and Advanced Pharmacological Treatments

Journal of Education, Health and Sport
Introduction and objective: Acne vulgaris is a common chronic inflammatory skin disease affecting hair and sebaceous follicles, characterized by skin lesions most commonly appearing on the face.
Krzysztof Dobrzeniecki, Anna Zygmunt, Karolina Karoń, Łukasz Karoń, Patrycja Karnas-Bogacka   +4 more
doaj   +1 more source

Cold plasma treatment for oral lichen planus: a retrospective case collection and proposal of a new clinical score

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objectives Oral lichen planus (OLP) is a chronic autoimmune mucosal disease with malignant potential and limited treatment options. This study evaluated the long‐term efficacy and safety of cold atmospheric plasma (CAP) therapy in therapy‐refractory OLP and introduced the novel Lichen Planus Severity Score (LPSS).
Christian Seebauer, Hans‐Robert Metelmann, Mohamed Falougy, Wolfram Kaduk, Lasse Kremer, Georg Daeschlein   +5 more
wiley   +1 more source

Rosacea and treatment with retinoids: a systematic review and meta-analysis

Therapeutic Advances in Chronic Disease
Background: Rosacea is a common inflammatory disease. Four clinical rosacea subtypes have been described, with the papulo-pustular being the most common.
Alberto Sticchi, Flavio Fiorito, Shaniko Kaleci, Alessia Paganelli, Marco Manfredini, Caterina Longo   +5 more
doaj   +1 more source

Synchronizing pharmacotherapy in acne with review of clinical care

Indian Journal of Dermatology, 2017
Acne is a chronic inflammatory skin disease that involves the pathogenesis of four major factors, such as androgen-induced increased sebum secretion, altered keratinization, colonization of Propionibacterium acnes, and inflammation.
Sarvajnamurthy Aradhya Sacchidanand, Koushik Lahiri, Kiran Godse, Narendra Gajanan Patwardhan, Anil Ganjoo, Rajendra Kharkar, Varsha Narayanan, Dhammraj Borade, Lyndon D'souza   +8 more
doaj   +1 more source

Monilethrix Presenting With Diffuse Fragile Hair in an Adult Female

JEADV Clinical Practice, EarlyView.
Mandy Robertson, Jeffrey Donovan
wiley   +1 more source

S1 Guideline: Therapy of generalized pustular psoriasis

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary The S1 guideline “Therapy of generalized pustular psoriasis (GPP)” is a German guideline developed in accordance with the criteria of the AWMF. The full version addresses clinical presentation, pathogenesis, diagnosis and differential diagnosis, comorbidities, and therapy.
Rotraut Mößner, Neda Cramer, Sascha Gerdes, Ulrike Hüffmeier, Andreas Körber, Kai Krause, Christian Kromer, Katharina Antonia Langen, Sandra Philipp, Knut Schäkel, Michael P. Schön, Michael Schultheis, Lukas Sollfrank, Petra Staubach, Michael Sticherling, Johannes Wohlrab, Dagmar Wilsmann‐Theis, Cornelia Paul   +17 more
wiley   +1 more source

Dramatic Response of Nail Psoriasis to Infliximab

Case Reports in Medicine, 2011
Nail psoriasis, affecting up to 50% of psoriatic patients, is an important cause of serious psychological and physical distress. Traditional treatments for nail psoriasis, which include topical or intralesional corticosteroids, topical vitamin D ...
Gilles Safa, Laure Darrieux
doaj   +1 more source

THE ELIXIR OF YOUTH: RETINOID REVELATION [PDF]

Bulletin of Pharmaceutical Sciences. Assiut University
The integumentary system, mostly made up of skin tissue, is the most substantial system in the human skeleton, serving as an essential shield against a myriad of detrimental agents.
Sneha Nawale, Jeslina Roshni Benadict, Chenna Harshan Reddy Yenugula, Jagadish Swamy M, Monika Nijhawan   +4 more
doaj   +1 more source

Epidermal Delivery of Retinyl Palmitate Loaded Transfersomes: Penetration and Biodistribution Studies

Pharmaceutics, 2020
The alteration of retinoids levels in the skin can cause different disorders in the maturation of epithelial skin cells. Topical administration of these lipophilic molecules is a challenge that can be addressed by encapsulation into drug delivery systems.
Eloy Pena-Rodríguez, Mari Carmen Moreno, Bárbara Blanco-Fernandez, Jordi González, Francisco Fernández-Campos   +4 more
doaj   +1 more source