Topiramate Induced Restless Legs Syndrome: Case Report
Several medications can exacerbate or cause Restless Legs syndrome (RLS). Topiramate is an antiepileptic drug used to epilepsy and migraine treatment. In literature, number of case with topiramate induced RLS is very rare.
Selda Korkmaz, Murat Aksu
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Topiramate modulates trigeminal pain processing in thalamo-cortical networks in humans after single dose administration. [PDF]
Migraine is the sixth most common cause of disability in the world. Preventive migraine treatment is used to reduce frequency, severity and duration of attacks and therefore lightens the burden on the patients' quality of life and reduces disability ...
Julia M Hebestreit, Arne May
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Nephrolithiasis and Nephrocalcinosis From Topiramate Therapy in Children With Epilepsy
Introduction: Adults treated with topiramate may develop nephrolithiasis, but its frequency in children on topiramate is unknown. Topiramate inhibits renal carbonic anhydrase, which can lead to renal tubular acidosis and hypercalciuria.
Sarah M. Barnett +4 more
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Add-on Effect of Levetiracetam on Cognitive Activity of Carbamazepine and Topiramate Treated Healthy Rats [PDF]
Background: Many antiseizure drugs are used for non-epileptic indications like bipolar disorder, anxiety, neuropathic pain, prophylaxis of migraine, etc.
Priti Dhande +3 more
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Agranulocytosis Associated with Topiramate: A Case Report and Review of Published Cases
A 41-year-old female presented to the hospital with sore throat and shortness of breath. She was hypoxic with an oxygen saturation of 87% in room air. Physical examination revealed swollen uvula with exudates.
Saroj Lohani +3 more
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Comparison between baclofen and topiramate in alcohol dependence: A prospective study
Introduction: Baclofen and topiramate are GABAergic drugs, and both have been recommended for the treatment of alcohol dependence as anticraving agent. Several studies have demonstrated the effect of baclofen and topiramate as anticraving, but none has ...
Nimmi A Jose +3 more
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Psychotic symptoms due to topiramate
Topiramate is an antiepileptic drug prescribed in the treatment of numerous psychiatric disorders and in epilepsy. Topiramate exerts its antiepileptic effect through different mechanisms, such as by the blockage of sodium channels, increasing GABAergic
Gülay Oğuz +3 more
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A trial of topiramate for patients with hereditary spinocerebellar ataxia
In an open pilot trial, six patients with various hereditary forms of spinocerebellar ataxia (SCA) were assigned to topiramate (50 mg/day) for 24 weeks. Four patients completed the protocol without adverse events.
Shiroh Miura +5 more
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Probable topiramate-induced diarrhea in a 2-month-old breast-fed child — A case report
An infant developed a severe condition of recurrent and persistent watery diarrhea at 40 days of age. The child had been partially breast-fed, and the mother used topiramate for epilepsy.
Tone Westergren +4 more
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Topiramate treatment is neuroprotective and reduces oligodendrocyte loss after cervical spinal cord injury. [PDF]
Excess glutamate release and associated neurotoxicity contributes to cell death after spinal cord injury (SCI). Indeed, delayed administration of glutamate receptor antagonists after SCI in rodents improves tissue sparing and functional recovery. Despite
John C Gensel +3 more
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