Results 121 to 130 of about 66,338 (163)

Typhoid Toxin of Salmonella enterica Induces ISG15 Responses Mediating Host Cell Survival and Counteracting Intracellular Infection

Molecular Microbiology, Volume 125, Issue 6, Page 475-492, June 2026.
Toxigenic Salmonella enterica exocytose the typhoid toxin during infection causing host cell DNA damage, which activates a Type‐1 Interferon‐like response characterised by interferon‐stimulated gene 15 (ISG15) expression. ISG15 was required for host cell survival during Interferon responses and suppressed intracellular growth of Salmonella. Thus, ISG15
Daniel S. Stark, Michelle King, Angela E. M. Ibler, Salma Srour, Francesca Brown, James Sheffield, Nadia Baseer, Ellen G. Vernon, Yifeng Zhang, Christopher Staples, Lilliana Radoshevich, Daniel Humphreys   +11 more
wiley   +1 more source

Cellular strategies for repairing trapped protein-DNA complexes. [PDF]

Front Pharmacol
Sideridou M, Machli DI, Lontra D, Rampias T.   +3 more
europepmc   +1 more source

Metabolic Enzyme MeHNL11 Regulates MeCAS1b Transcription for Cyanide Reutilization in Response to Nitrate Deficiency in Cassava

Plant Biotechnology Journal, Volume 24, Issue 6, Page 4121-4135, June 2026.
ABSTRACT Cassava (Manihot esculenta Crantz) exhibits exceptional tolerance to infertile soils and contains abundant cyanogenic glucosides (CGs). Previous research has indicated that CGs can serve as a significant reservoir of organic nitrogen in plants.
Weitao Mai, Ruxue Bao, Xiaocheng Liu, Mengtao Li, Jinling Zhao, Huaifang Zhang, Yuan Yao, Haiyan Wang, Wenquan Wang, Changying Zeng, Xin Chen   +10 more
wiley   +1 more source

Evolution and recent advances in antibody-drug conjugate therapy for lung cancer: a comprehensive systematic review based on the Trialtrove database (inception to July 1, 2025). [PDF]

Front Oncol
Chen Y, Zhang Y, Tian C, Li Z, Guo G.
europepmc   +1 more source

Legume genome structures and histories inferred from Cercis canadensis and Chamaecrista fasciculata genomes

The Plant Journal, Volume 126, Issue 5, June 2026.
SUMMARY The legume family originated ca. 60–65 million years ago and soon diversified into at least six lineages (now extant subfamilies). The signal of whole genome duplications (WGD) is apparent in species sampled from all six subfamilies. The early diversification has posed difficulties for resolving the legume backbone structure and the timing of ...
Hyun‐oh Lee, Jacob S. Stai, Qiaoji Xu, Thulani Hewavithana, Pratheesh Soman, Rabnoor Batra, Alex Liu, Brandon D. Jordan, Rachel Walstead, Jerry Jenkins, Melissa Williams, Jenell Webber, Jane Grimwood, John T. Lovell, Tomáš Brůna, Shengqiang Shu, Keykhosrow Keymanesh, Joanne Eichenberger, Jeremy Schmutz, David M. Goodstein, Kerrie Barry, David Sankoff, Lingling Jin, James H. Leebens‐Mack, Steven B. Cannon   +24 more
wiley   +1 more source

Structural interactions of BWC0977 with Klebsiella pneumoniae topoisomerase IV and biochemical basis of its broad-spectrum activity. [PDF]

Commun Biol
Nandishaiah R, Murakami S, Hameed P S, Aoki M, Okada U, Yamashita E, Venkatesan S, Bharatham N, Sarma S, Shanbhag AP, Sharma S, Rao R, Ramachandran V, Balasubramanian V, Datta S, Katagihallimath N.   +15 more
europepmc   +1 more source

Redox Disruption Induced by Saquayamycin B1 Promotes Cytotoxicity in Resistant Melanoma Cells

ChemMedChem, Volume 21, Issue 10, 27 May 2026.
Saquayamycin B1 (SQ‐B1), an antibiotic isolated from Streptomyces sp. I072, triggers cell death in different melanoma cell lines, including chemoresistant SK‐MEL‐5. SQ‐B1 elevates O2•‐ and NO• on both sides of the membrane and blocks glutathione transferase (GSTP‐1) and glutathione reductase (GSR), destabilizing the GSH/GSSG antioxidant system.
Geovana Guedes Silvestre, Thalisson Amorim de Souza, Alan Ferreira Alves, Valeria Dutan‐Patiño, Jean‐Michel Huvelin, Mathilde Gourdel, Mikael Croyal, Samuel Cibulski, Demetrius Antonio Machado de Araújo, Marcus Tullius Scotti, Josean Fechine Tavares, Angela Tesse, El‐Hassan Nazih, Marianna Vieira Sobral   +13 more
wiley   +1 more source

Case Report: Complete response to the novel NaPi2b-targeting ADC YL205 in heavily pretreated platinum-resistant ovarian cancer. [PDF]

Front Oncol
Tang YX, Xiao H, Tang ZZ, Jian L, Guo X.
europepmc   +1 more source

Lung Auscultation for Detecting Interstitial Lung Disease in Patients with Newly Diagnosed Systemic Sclerosis: Retrospective Cohort Study. [PDF]

Diagnostics (Basel)
Wireko FW, Tzilas V, Anim-Koranteng C, Ahmed ASS, Yeboah-Kordieh YA, Makol A, Ryu JH.   +6 more
europepmc   +1 more source