Results 241 to 250 of about 146,499 (323)

The Effect of Topoisomerase II Beta Mutations on the Transcription/Double-Strand Break Complex [PDF]

, 2018
Michelle Nichole Peru
openalex  

Comprehensive Analysis of Structure Activity Relationships in Quinoxaline Derivatives Covering Antimicrobial Applications

ChemistrySelect, Volume 11, Issue 14, 13 April 2026.
ABSTRACT Antimicrobial resistance (AMR) has emerged as one of the most critical global health challenges, undermining the clinical efficacy of existing antibiotics and threatening modern therapeutic strategies. The ongoing misuse and overuse of antimicrobial agents have accelerated the evolution of resistant bacterial strains and parasites ...
Subham Kumar Vishwakarma, Fernando Rogério Pavan, Cesar Augusto Roque‐Borda   +2 more
wiley   +1 more source

Design, synthesis, and anticancer evaluation of a novel imine-linked covalent organic framework correlated to molecular docking and DFT insights. [PDF]

RSC Adv
Abdelnasser E, Allehyani ES.
europepmc   +1 more source

Tricyclic 1,5-naphthyridinone oxabicyclooctane-linked novel bacterial topoisomerase inhibitors as broad-spectrum antibacterial agents-SAR of left-hand-side moiety (Part-2)

, 2015
Sheo B. Singh, David E. Kaelin, Jin Wu, Lynn Miesel, Christopher M. Tan, Todd A. Black, Ravi P. Nargund, Peter T. Meinke, David B. Olsen, Armando Lagrutta, Jun Lu, Sangita B. Patel, Keith Rickert, Robert F. Smith, S.M. Soisson, Edward C. Sherer, Leo A. Joyce, Changqing Wei, Xuanjia Peng, Xiu Wang, Hideyuki Fukuda, Ryuta Kishii, Masaya Takei, Hisashi Takano, Mitsuhito Shibasaki, Masanobu Yajima, Akinori Nishimura, Takeshi Shibata, Yasumichi Fukuda   +28 more
openalex   +1 more source

ChitoSilkBioPatch: A bio‐inspired wound dressing scaffold for antibiotic‐free diabetic wound management

VIEW, Volume 7, Issue 2, April 2026.
We present ChitoSilkBioPatch, a maleimide‐functionalized chitosan/dACM hydrogel integrated with a stretchable nanopatterned silk mesh to provide intrinsic, antibiotic‐free antibacterial activity and bioactive wound support. The scaffold eliminates S. aureus and P.
Dorsa Dehghan‐Baniani, Babak Mehrjou, Yucong Li, Zhaowei Jiang, Xiaomin Lu, Yin Xiao, Huanxiong Chen, Tsz Lam Yiu, Chi Chiu Wang, Hongkai Wu, Gang Li, Paul K. Chu, Wayne Yuk Wai Lee   +12 more
wiley   +1 more source

Crystal structure of the 65-kilodalton amino-terminal fragment of DNA topoisomerase I from the gram-positive model organism Streptococcus mutans

, 2019
Jesse A. Jones, Kirk E. Hevener
openalex   +1 more source

Circumscribed Morphea Successfully Treated With Excimer Laser: Analysis of Histopathological Changes

The Journal of Dermatology, Volume 53, Issue 4, Page 691-695, April 2026.
ABSTRACT Localized scleroderma (LSc) is an autoimmune condition characterized by localized cutaneous sclerosis, sometimes extending into deeper tissues. Phototherapy, including excimer laser therapy (ELT), is considered an effective and minimally invasive treatment option for patients without extracutaneous involvement.
Takuya Takahashi, Takehiro Takahashi, Yuichiro Segawa, Kenta Oka, Toshiya Takahashi, Yoshihide Asano   +5 more
wiley   +1 more source

Topoisomerases regulate alternative transcription start site selection in yeast. [PDF]

G3 (Bethesda)
Elgood Hunt E, Vivori C, Albihlal WS, van Werven FJ.   +3 more
europepmc   +1 more source

Bacterial Extracellular Vesicles in Biomedical Research and Clinical Translation

Microbial Biotechnology, Volume 19, Issue 4, April 2026.
Bacterial membrane vesicle biomedical applications. ABSTRACT Bacterial Extracellular Vesicles (bEVs) are lipid (single‐ or double‐bilayer) nanostructures secreted by virtually all bacteria that play fundamental roles in intercellular communication and have emerged as powerful, multifunctional tools in biomedicine. Their intrinsic ability to encapsulate
Alejandro Arce‐Rodríguez, Javier De la Peña Noya, José Manuel Borrero‐de Acuña   +2 more
wiley   +1 more source

Studies of Nε-Lysine Acetylation Modification on Escherichia coli Topoisomerase I

, 2017
Qingxuan Zhou
openalex   +2 more sources