Predicting hospice eligibility among dementia patients using language models
Alzheimer's &Dementia, Volume 21, Issue 11, November 2025.Abstract INTRODUCTION Alzheimer's disease and related dementias (ADRD) are increasing in prevalence, and access to potential benefits of hospice care remains challenging. Large language models (LLMs), like GPT‐4o, applied to electronic health records (EHRs) could support decisions by estimating mortality risk.
Thomas H. McCoy, Roy H. Perlis
wiley +1 more source
Management of xylazine toxicity, overdose, dependence, and withdrawal: A systematic review
The American Journal on Addictions, Volume 34, Issue 6, Page 589-602, November 2025.Abstract Background and Objectives Xylazine, an alpha‐2‐adrenergic agonist, has been increasingly implicated in substance use and overdose crises. However, little is known about its effects on humans. With the growing public health crisis surrounding xylazine, it has become important to recognize and promptly manage symptoms of xylazine toxicity ...
Philipa Owusu‐Antwi +4 more
wiley +1 more source
Patterns in blood pressure medication use in US incident dialysis patients over the first 6 months. [PDF]
, 2013 BACKGROUND: Several observational studies have evaluated the effect of a single exposure window with blood pressure (BP) medications on outcomes in incident dialysis patients, but whether BP medication prescription patterns remain stable or a single ...
Bandeen-Roche, K +16 more
core +2 more sources
Renal drug metabolism in humans: the potential for drug–endobiotic interactions involving cytochrome P450 (CYP) and UDP-glucuronosyltransferase (UGT) [PDF]
, 2013 This item is under embargo for a period of 12 months from the date of publication, in accordance with the publisher's policy. ‘This is the peer reviewed version of the following article: Knights, K. M., Rowland, A. and Miners, J. O.
Knights, Kathleen Mary +2 more
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Current Management of Heart Failure: When to Refer to Heart Failure Specialist and When Hospice is the Best Option. [PDF]
, 2015 Heart failure is a common syndrome caused by different abnormalities of the cardiovascular system that result in impairment of the ventricles in filling or ejecting blood.
Bozorgnia, Behnam, Mather, Paul J
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Regulation of human CYP2C9 expression by electrophilic stress involves AP-1 activation and DNA looping [PDF]
, 2014 CYP2C9 and CYP2C19 are important human enzymes that metabolize therapeutic drugs, environmental chemicals and physiologically important endogenous compounds.
Goldstein, J. A. +4 more
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Myxomatous mitral valve disease in a Shih Tzu dog [PDF]
, 2017 An 11-year-old intact male Shih Tzu dog was referred to the University Veterinary Hospital (UVH) with history of coughing and laboured breathing. Auscultation revealed that the dog had a left systolic heart murmur grade V/VI at the base of the heart ...
Khor, Kuan Hua, Teoh, Y. B.
core
Pharmacokinetics of Torsemide in Patients with Decompensated and Compensated Congestive Heart Failure [PDF]
, 1998 Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/97165/1/j.1552-4604.1998.tb04810.x ...
Cavalier +8 more
core +1 more source
Association between PCSK9 inhibitors and acute kidney injury: a pharmacovigilance study
Frontiers in PharmacologyBackgroundPCSK9 inhibitors are a novel class of lipid-lowering medications, and numerous clinical studies have confirmed their significant role in improving the progression of chronic kidney disease.
Hailing Liu
doaj +1 more source