Results 81 to 90 of about 2,244 (195)

Association between PCSK9 inhibitors and acute kidney injury: a pharmacovigilance study

Frontiers in Pharmacology
BackgroundPCSK9 inhibitors are a novel class of lipid-lowering medications, and numerous clinical studies have confirmed their significant role in improving the progression of chronic kidney disease.
Hailing Liu
doaj   +1 more source

Orally administered torsemide in horses: pharmacokinetic and pharmacodynamic studies [PDF]

, 2018
Diuretic therapy is the mainstay for management of congestive heart failure in horses. Loop-diuretic medications in horses have been restricted to injectable medications because currently, no data support the use of orally-administered loop diuretics ...
Ferlini Agne, Gustavo
core  

Clinical evaluation of a novel fixed-dose combination tablet (Sentorpil® ForteGold) versus compounded powdered medications in dogs with myxomatous mitral valve disease: a randomized, double-blind study

Frontiers in Veterinary Science
IntroductionMyxomatous mitral valve disease (MMVD) is a prevalent cardiac condition in older, small-breed dogs, often managed with multiple medications.
Jiyoung Park, Jiyoon Lee, Sang-Joon Lee, Changbaig Hyun   +3 more
doaj   +1 more source

Rationale and protocol of the LAQUA-HF trial: a factorial randomised controlled trial evaluating the effects of neurohormonal and diuretic agents on health-status reported outcomes in heart failure patients

BMJ Open
Introduction The current guidelines strongly recommend early initiation of multiple classes of cardioprotective drugs for patients with heart failure with reduced ejection fraction to improve prognosis and health status.
Yohei Numasawa, Ikuko Ueda, Shun Kohsaka, Yasuyuki Shiraishi, Takashi Kohno, Toshikazu Tanaka, Nobuhiro Ikemura, Makoto Takei, Mitsuyoshi Urashima, Shintaro Nakano, Yuji Nagatomo, Takenori Ikoma, Tomohiko Ono, Munehisa Sakamoto, Kei Nishikawa, Daihiko Hakuno, Ryo Nakamaru   +16 more
doaj   +1 more source

Development of Fast Dissolving Tablets of Torsemide. [PDF]

, 2014
Oral mucosal drug delivery system is widely applicable as novel site for administration of drug for immediate and controlled release action by preventing first pass metabolism and enzymatic degradation due to GI microbial flora.
Ponnammal Asmi, S
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DRUG INDUCED DYSELECTROLYTEMIA –A CASE REPORT

, 2017
: Spiranolactone and Eplerenone were belongs to the class of potassium sparing diuretics where as Torsemide belongs to the loop diuretic class, they mainly acts by blocking the function of aldosterone hormone to retain the sodium and excrete potassium ...
Kusuma Kumari.S* , Rajesh .G , Dr. Siddarama. R
core   +1 more source

Lost to Follow‐Up in Pragmatic Trials With Remote Follow‐Up: Insights From CONNECT‐HF and TRANSFORM‐HF

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Pragmatic trials commonly use remote follow‐up to reduce participant burden and costs. However, these approaches may increase the risk of lost to follow‐up (LTFU).
Satoshi Shoji, Lisa A. Kaltenbach, Haolin Xu, Robert J. Mentz, Bradi B. Granger, Gregg C. Fonarow, Javed Butler, Joseph B. Lerman, Manasi Tannu, Veraprapas Kittipibul, Min Soo Cho, Eric J. Velazquez, Stephen J. Greene, Kevin J. Anstrom, Amanda Harrington, Christopher B. Granger, Adrian F. Hernandez, Adam D. DeVore   +17 more
doaj   +1 more source

On the Stability of Zwitterions of Pyridine Sulfonylureas: The Effect of Isosterism, Acidity, and Microsolvation

, 2016
Pyridine sulfonylureas (PSUs) are known to exist in zwitterionic form in the solid phase. For example, torsemide, a diuretic drug, exists in three polymorphic forms: two of them in the zwitterionic state and one in the “partial zwitterionic” state ...
Devendra K. Dhaked (1859779), Prasad V. Bharatam (662055)   +1 more
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Therapeutics Letter 17

, 1997
Therapeutics Letter 17 reviews the five newer drugs famciclovir, valacyclovir, torsemide, etodolac, and naltrexone. Conclusions: Anti-viral drugs have a modest beneficial effect if given early (rash 50 yr) with moderate to severe rash or pain associated ...
Therapeutics Initiative (University of British Columbia)
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Torsemide vs. furosemide in congestive heart failure: a systematic-review and meta-analysis on mortality and rehospitalization

BACKGROUND: Current guidelines suggest the use of loop diuretics as the preferred agent for decongestion in patients with heart failure. However, there is no clear evidence as to superiority of one loop diuretic over the other.
Menghrajani, Rajiv Hans, Lemonjava, Irakli, Alfonso, Pia Gabrielle, Polintan, Edgar Theodore, Shah, Samir, Lo, Kevin Bryan, Rangaswami, Janani, Gudushauri, Nino, Azmaiparashvili, Zurab   +8 more
core   +1 more source