Results 71 to 80 of about 3,074 (210)

Сучасні аспекти діуретичної терапії хронічної серцевої недостатності у розрізі доказової медицини [PDF]

, 2015
У дослідженні проведений аналіз показників ендотеліальної функції судин у хворих на хронічну серцеву недостатність під впливом різних схем діуретичної терапії: інтермітивного прийому фуросеміду та постійного прийому торасеміду пролонгованого вивільнення ...
Хребтій, Г.І.
core  

De Novo ACTN2 Variant in a Chinese Neonate With Left Ventricular Non‐Compaction and Metabolic Disturbances: A Rare Case Report

Annals of Noninvasive Electrocardiology, Volume 31, Issue 1, January 2026.
This study reports a 2‐day‐old neonate whose echocardiographic features are consistent with LVNC. The patient exhibited severe metabolic abnormalities and experienced recurrent heart failure episodes temporally associated with these metabolic derangements.
Jinqiu Huang, Ziyue Zhang, Juxian Yang
wiley   +1 more source

The Role of Transporters in the Pharmacokinetics of Orally Administered Drugs [PDF]

, 2009
Drug transporters are recognized as key players in the processes of drug absorption, distribution, metabolism, and elimination. The localization of uptake and efflux transporters in organs responsible for drug biotransformation and excretion gives ...
Sarah Shugarts, Leslie Z. Benet, RL Juliano, MF Fromm, CP Landowski, N Mizuno, CY Wu, GL Amidon, C Srimaroeng, ZM Zaïr, G Ciarimboli, B Hagenbuch, Y Toyoda, SF Zhou, H Kusuhara, S Choudhuri, BL Urquhart, AD Mottino, LW Chinn, K Maeda, T Nakamura, JE Montfoort van, M Okabe, L Li, LM Satlin, C Mahagita, A Kosters, T Takagi, NA Kasim, Y Yang, LZ Benet, H Lennernäs, N Li, M Katoh, X Cao, R Hayeshi, JM Arthur, D Sun, ML Chen, Y Shirasaka, U Fagerholm, CY Wu, X Cao, CL Cummins, CL Cummins, UI Schwarz, K Westphal, JS Lee, AL Sesink, Y Su, H Glaeser, Y Koitabashi, A Dahan, B Greiner, JM Custodio, RG Tirona, Y Su, T Watanabe, YY Lau, HX Zheng, JW Deng, Y Shu, X Tian, N Zelcer, RB Parker, LZ Benet, GA Kullak-Ublick, C Solas, S Zhou, SX Peng, C Tannergren, S Sahin, Y Kato, C Luna- Tortós, K Engel, M Zhou, BL Urquhart, MO Magnusson, N Ishiguro, Q Wang, DG Bailey, SR Vavricka, U Muenster, K Takenaka, DA Volpe, C Hilgendorf, M Lohitnavy, T Lavé, SS Buck De, Z Wang, N Parrott, A Bonen, M Grube, W Lee, MJ Bijvelds, JH Gray, RP Owen, A Bodo, Q Tian, L Ci, RD Huber, B Gao, G Jedlitschky, M Farias, SY Yao, D Kirat, D Meredith, I Knutter, DA Groneberg, M Hayer-Zillgen, S Sakamoto, H Li, JY Li, H Yabuuchi, I Elimrani, ILMH Aye, JD Allen, O Janneh, K Fujiwara, H Potschka, E Pollex, F Boraldi, W Lin, KR Robillard, AJ Smith, M Hirano, E Jigorel, EM Leslie, RB Kim, S Khamdung, S Halwachs, A Geick, O Burk, HR Kast, J Staudinger, M Assem, I Szatmari, M Ananthanarayanan, JJ Eloranta, Y Miki, JM Maglich, D Jung, Y Morita, S Hoffmeyer, Y Kurata, SY Yi, FA Jong de, A Sparreboom, A Sparreboom, W Zhang, Y Nishizato, J Mwinyi, M Niemi, M Niemi, I Ieiri, MK Pasanen, W Zhang, DA Katz, X Xiang, S Oswald, SV Vormfelde, M Miura   +161 more
core   +3 more sources

A Case of Malignant Hyperthermia Following Intubation With Rocuronium

Case Reports in Critical Care, Volume 2026, Issue 1, 2026.
Background Malignant hyperthermia (MH) is an inherited autosomal‐dominant disorder of ryanodine receptors. While typically associated with exposure to inhaled anesthetics or depolarizing neuromuscular blocking agents (NMBAs), there have been reported cases following exposure to other conditions and medications including nondepolarizing neuromuscular ...
Kristin Woodring, Nicholas Liotta, Dominick Roto, Christine M. Groth, Naohiro Komura   +4 more
wiley   +1 more source

Anterolateral Papillary Muscle Rupture After Acute Myocardial Infarction Leading to Severe Mitral Regurgitation: A Case Report

Clinical Case Reports, Volume 13, Issue 12, December 2025.
Mitral anterolateral papillary muscle rupture with partial valve body prolapse and severe mitral regurgitation after acute myocardial infarction (ultrasound schematic). ABSTRACT Due to dual blood supply, ischemic mitral anterolateral papillary muscle rupture is less common than that of posteromedial papillary muscle and is rare in acute myocardial ...
Zeyan Liu, Shou Zhou, Xuexiang Li, Qi Yang, Xiaodong Pan   +4 more
wiley   +1 more source

Simple Spectrophotometric Determination of Torsemide in Bulk Drug and in Formulations

E-Journal of Chemistry, 2008
A simple and cost effective spectrophotometric method is described for the determination of torsemide in pure form and in pharmaceutical formulations.
Marothu Vamsi Krishna, Dannana Gowri Sankar   +1 more
doaj   +1 more source

Prevalence of thiamine deficiency in heart failure patients on long-term diuretic therapy

Journal of the Practice of Cardiovascular Sciences, 2015
Background: Loop diuretics are an integral part of heart failure management. It has been shown that loop diuretics cause thiamine deficiency (TD) by increasing its urinary loss. The aim of this study was to determine the prevalence of TD in heart failure
Shrenik Doshi, T Velpandian, Sandeep Seth, S K Maulik, Balram Bhargava, Vinay K Bahl   +5 more
doaj   +1 more source

Clinical Trials With Pragmatic Elements: A Review of Use Cases and Real‐World Data Utilization

Clinical Pharmacology &Therapeutics, Volume 118, Issue 6, Page 1350-1365, December 2025.
Clinical trials with pragmatic elements can capture diverse patient populations, enable efficient follow‐up, and reflect routine clinical practices; yet there is limited understanding of their design features, characteristics, and use of real‐world data (RWD). Based on a targeted search of PubMed/EMBASE (Jan‐2016 to Jul‐2024), a review was conducted to
Le Su, Lei Chen, Seema Betigeri, Nancy Dreyer, Helga Gardarsdottir, Rachele Hendricks‐Sturrup, Mehmet Burcu   +6 more
wiley   +1 more source

Which diuretics are safe and effective for patients with a sulfa allergy? [PDF]

, 2007
Diuretics that do not contain a sulfonamide group (eg, amiloride hydrochloride, eplerenone, ethacrynic acid, spironolactone, and triamterene) are safe for patients with an allergy to sulfa.
Healy, Ron, Jankowski, Terry Ann, 1951-
core  

Urate Handling in the Human Body [PDF]

, 2016
Elevated serum urate concentration is the primary cause of gout. Understanding the processes that affect serum urate concentration is important for understanding the etiology of gout and thereby understanding treatment. Urate handing in the human body is
David Hyndman, Jeffrey N. Miner, Sha Liu
core   +1 more source