Results 101 to 110 of about 12,796 (264)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Signed total strong Roman domination in graphs [PDF]

open access: yesDiscrete Mathematics Letters, 2022
Maryam Hajjari   +1 more
doaj   +1 more source

Characterization of Cubic Graphs G with irt(G) = Irt(G) = 2

open access: yesDiscussiones Mathematicae Graph Theory, 2014
A subset S of vertices in a graph G is called a total irredundant set if, for each vertex v in G, v or one of its neighbors has no neighbor in S −{v}. The total irredundance number, ir(G), is the minimum cardinality of a maximal total irredundant set of ...
Eslahchi Changiz   +2 more
doaj   +1 more source

Signed total Roman domination in graphs

open access: yesJournal of Combinatorial Optimization, 2015
Published by De Gruyter Open ...
openaire   +4 more sources

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Partial Total Domination in Hypergraphs

open access: yesMathematics
This paper establishes fundamental results for partial total domination in hypergraphs. We present tight bounds for the partial total domination number in k-uniform hypergraphs, demonstrate relationships with classical domination parameters, and provide ...
Abdulkafi Sanad, Chaoqian Li
doaj   +1 more source

Bounding the Locating-Total Domination Number of a Tree in Terms of Its Annihilation Number

open access: yesDiscussiones Mathematicae Graph Theory, 2019
Suppose G = (V,E) is a graph with no isolated vertex. A subset S of V is called a locating-total dominating set of G if every vertex in V is adjacent to a vertex in S, and for every pair of distinct vertices u and v in V −S, we have N(u) ∩ S ≠ N(v) ∩ S ...
Ning Wenjie, Lu Mei, Wang Kun
doaj   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

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