Results 111 to 120 of about 261,417 (310)

Comprehensive Fractionation of Antioxidants and GC-MS and ESI-MS Fingerprints of Celastrus hindsii Leaves

Medicines, 2019
Background: In this study, column chromatography was applied to separate active fractions from the ethyl acetate extract of Celastrus hindsii, a medicinal plant widely used in Southern China, Northern Vietnam, Myanmar, and Malaysia.
Tran Duc Viet, Tran Dang Xuan, Truong Mai Van, Yusuf Andriana, Ramin Rayee, Hoang-Dung Tran   +5 more
doaj   +1 more source

Cognitive tests used in chronic adult human randomised controlled trial micronutrient and phytochemical intervention studies [PDF]

, 2010
In recent years there has been a rapid growth of interest in exploring the relationship between nutritional therapies and the maintenance of cognitive function in adulthood.
Anderson, Anna L. Macready, Balk, Burgess, Claire M. Williams, Clarke, Detterman, Eussen, Fournier, Ho, Ivers, Jeremy P. E. Spencer, Judi A. Ellis, Knapp, Laurie T. Butler, Lezak, Manly, Maylor, McDaniel, Orla B. Kennedy, Phillips, Rabbitt, Reitan, Rosen, Rugg, Santos, Wechsler, Wechsler, Wesnes   +28 more
core   +1 more source

Integrative Approaches to Treating Cellular Senescence in Kidney Disease

Advanced Science, EarlyView.
ABSTRACT Cellular senescence in the kidney plays a crucial role in the progression of acute kidney injury and chronic kidney disease. Therapeutic approaches targeting senescent cells, such as small molecule senolytic and senomorphic drugs, display efficacy in preclinical models.
Tomoka Misawa, Amruta A, LaTonya J. Hickson, Joy Wolfram   +3 more
wiley   +1 more source

Comprehensive Analysis of Phytochemical Composition, Antioxidant Potential, and Antibacterial Activity of T. polium

Separations
This study aims to thoroughly examine the chemicals and effects of the ethanol extract from T. polium’s upper parts. We used the Soxhlet method for extraction, resulting in an extract with a significant yield of 20.6%.
Zineb Timizar, Khalida Boutemak, Amel Hadj Ziane-Zafour, Nabil Touzout, Hichem Tahraoui, Bassem Jaouadi, Meriem Zamouche, Mohammed Kebir, Jie Zhang, Abdeltif Amrane   +9 more
doaj   +1 more source

The leaves of Mediterranean mandarin could be used as an important source of hesperidin, nobiletin and tangeretin. : S20P04 [PDF]

, 2012
Citrus are rich in flavonoids such as flavones and flavanones. Recent studies have shown that these phytonutrients play a beneficial role for human health.
Bidel, Luc P.R., Durand, Marie V.S, Fanciullino, Anne Laure, Froelicher, Yann, Jay-Allemand, Christian, Ollitrault, Patrick   +5 more
core  

Soluble and insoluble-bound phenolics and antioxidant activity of various industrial plant wastes [PDF]

, 2019
The potential of selected industrial food wastes from juice and nut production including apple peel, apple pomace, pomegranate peel, pomegranate seed, chestnut shell, and black carrot pomace as resources for natural antioxidants was investigated. Soluble
Gulsunoglu, Zehra, Karbancioglu-Guler, Funda, Kilic-Akyilmaz, Meral, Raes, Katleen   +3 more
core   +2 more sources

Multimodal AI‐Driven Identification of Dehydrocostus Lactone as a Potent Renal Fibrosis Attenuator Targeting IQGAP1

Advanced Science, EarlyView.
Renal fibrosis, a hallmark of CKD, lacks effective treatments. Herein, we developed a multimodal AI model (TCM‐SPred) to identify anti‐fibrotic agents and found that dehydrocostus lactone (DCL) targets IQGAP1 to inhibit Wnt signaling, blocking the interaction between IQGAP1 and CCT3, demonstrating potent anti‐fibrotic activity in vitro and in vivo ...
Weijiang Lin, Wenzhuo Xu, Kang Liu, Ping Wang, Zhenzhen Zhu, Wenyu Lu, Zhe Zheng, Xiaoqian Peng, Xunkai Yin, Shulan Mei, An Pan, Jian Liu, Lihong Hu   +12 more
wiley   +1 more source

Dual‐Targeting Cuproptosis and Mitophagy via a Flavopiridol‐Copper Nanoplatform Potentiates Immunotherapy Against Uveal Melanoma

Advanced Science, EarlyView.
This study develops a GSH‐responsive nanoplatform, NP@Fla‐Cu, to co‐activate cuproptosis and excessive mitophagy in uveal melanoma. The nanoplatform enhances tumor‐specific copper delivery, depletes antioxidant defenses, and remodels the tumor immune microenvironment.
Hong Ren, Zhihong Deng, Sheng Lu, Jing Zhang, Wenbin Liu, Jia Tan   +5 more
wiley   +1 more source

Effects of Cultivation Conditions for Apples on Growth Rates of Fruit Fly Larvae and Contents of Phenolics [PDF]

, 2003
Apples were grown with 3 different alleyway groundcover management strategies, providing a wide range of nutrient availabilities to the trees, spanning the ranges normally found in both conventional and organic orchards.
Brandt, Kirsten, Ejlersen, Astrid, Lindhard Petersen, Hanne, Nørbæk, Rikke   +3 more
core  

Effects of acute consumption of fruit and vegetable puree-based drinks on vasodilation and oxidative status [PDF]

, 2012
Epidemiological studies indicate that diets rich in fruits and vegetables (F&V) are protective against cardiovascular diseases (CVD). Pureed \&V products retain many beneficial components, including flavonoids, carotenoids, vitamin C and dietary fibres ...
George, Trevor, Gordon, Mchael, Lovegrove, Julie, Niwat, Chutamat, Waroonphan, Saran   +4 more
core   +1 more source