Results 41 to 50 of about 49,681 (251)

Dose-Response Effects of Low-Dose Ionizing Radiation on Blood Parameters in Industrial Irradiation Workers

Dose-Response, 2022
While previous studies have focused on the health effects of occupational exposure of radiations on medical radiation workers, few have analyzed the dose-response relationship between low radiation doses and changes in blood parameters.
Jia-jia Guo, Ning Liu, Zheng Ma, Zi-jun Gong, Yue-lang Liang, Qi Cheng, Xin-guang Zhong, Zhen-jiang Yao   +7 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Involvement of GSTP1 in low dose radiation-induced apoptosis in GM12878 cells

Ecotoxicology and Environmental Safety
Background: Low-dose ionizing radiation-induced protection and damage are of great significance among radiation workers. We aimed to study the role of glutathione S-transferase Pi (GSTP1) in low-dose ionizing radiation damage and clarify the impact of ...
Jian Cui, Linwei Li, Shuang Wei, Yuanyun Wei, Yaqi Gong, Hongxia Yan, Yueqiu Yu, Xiang Lin, Hui Qin, Guoqing Li, Lan Yi   +10 more
doaj   +1 more source

System Health Awareness in Total-Ionizing Dose Environments [PDF]

IEEE Transactions on Nuclear Science, 2015
Understanding the relationship between the impact of radiation at the component and system levels is challenging. This paper discusses a hierarchical approach, based on Bayesian theory, to establish a mechanism for determining system health based on the status of, and interactions between, the radiation response of component parts.
Zachary J. Diggins, Nagabhushan Mahadevan, E. Bryn Pitt, Daniel Herbison, Gabor Karsai, Brian D. Sierawski, Eric J. Barth, Robert A. Reed, Ronald D. Schrimpf, Robert A. Weller, Michael L. Alles, Arthur F. Witulski   +11 more
openaire   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

HYGIENIC EVALUATION OF EXPOSURE DOSES FOR THE VORONEZH REGION POPULATION FROM THE NATURAL AND TECHNOGENOUSLY MODIFIED BACKGROUND

Радиационная гигиена, 2018
The purpose of the study was to estimate the doses to the Voronezh region population from natural sources of ionizing radiation and the technologically altered background in the territory of Voronezh Region.
Yu. I. Stepkin, M. K. Kuzmichev, O. V. Klepikov, E. М. Studenikina   +3 more
doaj   +1 more source

Analysis of Circuit Simulation Considering Total Ionizing Dose Effects on FinFET and Nanowire FET

Applied Sciences, 2021
In this study, we analyzed the total ionizing dose (TID) effect characteristics of p-type FinFET and Nanowire FET (NW-FET) according to the structural aspect through comparison of the two devices.
Hyeonjae Won, Myounggon Kang
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Combined effect of total ionizing dose and electromagnetic pulse on bipolar junction transistor [PDF]

AIP Advances
Electronic systems in complex radiation environments, such as space applications and nuclear power plants, face simultaneous threats from the cumulative damage of Total Ionizing Dose (TID) and the transient disturbances of Electromagnetic Pulse (EMP ...
Meiqing Zhong, Cui Meng, Yinong Liu, Chicheng Liu, Lanfeng Yuan, Xinfei Liu, Lin Wen, Qi Guo, Rui Ding, Weiheng Shao   +9 more
doaj   +1 more source