Results 41 to 50 of about 47,665 (252)
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
System Health Awareness in Total-Ionizing Dose Environments [PDF]
IEEE Transactions on Nuclear Science, 2015 Understanding the relationship between the impact of radiation at the component and system levels is challenging. This paper discusses a hierarchical approach, based on Bayesian theory, to establish a mechanism for determining system health based on the status of, and interactions between, the radiation response of component parts.
Zachary J. Diggins +11 more
openaire +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Involvement of GSTP1 in low dose radiation-induced apoptosis in GM12878 cells
Ecotoxicology and Environmental SafetyBackground: Low-dose ionizing radiation-induced protection and damage are of great significance among radiation workers. We aimed to study the role of glutathione S-transferase Pi (GSTP1) in low-dose ionizing radiation damage and clarify the impact of ...
Jian Cui +10 more
doaj +1 more source
Радиационная гигиена, 2018 The purpose of the study was to estimate the doses to the Voronezh region population from natural sources of ionizing radiation and the technologically altered background in the territory of Voronezh Region.
Yu. I. Stepkin +3 more
doaj +1 more source
Analysis of Circuit Simulation Considering Total Ionizing Dose Effects on FinFET and Nanowire FET
Applied Sciences, 2021 In this study, we analyzed the total ionizing dose (TID) effect characteristics of p-type FinFET and Nanowire FET (NW-FET) according to the structural aspect through comparison of the two devices.
Hyeonjae Won, Myounggon Kang
doaj +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Combined effect of total ionizing dose and electromagnetic pulse on bipolar junction transistor [PDF]
AIP AdvancesElectronic systems in complex radiation environments, such as space applications and nuclear power plants, face simultaneous threats from the cumulative damage of Total Ionizing Dose (TID) and the transient disturbances of Electromagnetic Pulse (EMP ...
Meiqing Zhong +9 more
doaj +1 more source
FEBS Letters, EarlyView.Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source