Results 51 to 60 of about 132,790 (364)

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Optimization of Ethanol-water Composition as Extraction Solvent in Producing Sambung Nyawa (Gynura Procumbens (Lour.) Merr.) Leaves Dry Extract [PDF]

, 2016
Sambung Nyawa leaves (Gynura procumbens (Lour.) Merr has been widely used as herbal medicine which requires a quality improvement of the dry extract for industrial production. Extraction solvent optimization is one key factor which determines the quality.
Hertiani, T. (Triana), Nareswari, T. L. (Tantri)   +1 more
core  

EFFECT OF DIFFERENT STORAGE CONDITIONS ON NUTRITIONAL AND QUALITY PARAMETERS OF 'SWEETHEART' CHERRY. [PDF]

, 2012
The sweet cherry ‘Sweetheart’, although having a short shelf life, is highly appreciated by consumers due to its organoleptic characteristics. Different storage methods were tested to study the maintenance of quality during a period of 27 days: 1) cold ...
Agulheiro-Santos, A.C., Cabrita, Maria João, Gonzalez, David, Lozano, Mercedes, Machado, Graça, Palma, Vera, Rato, A.E.   +6 more
core   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Antioxidant Activities, Total Phenolics and Flavonoids Content in Two Varieties of Malaysia Young Ginger (Zingiber officinale Roscoe)

Molecules, 2010
Ginger (Zingiber officinale Roscoe) is a well known and widely used herb, especially in Asia, which contains several interesting bioactive constituents and possesses health promoting properties.
Ali Ghasemzadeh, Hawa Z. E. Jaafar, Asmah Rahmat   +2 more
doaj   +1 more source

Inactivation of Escherichia coli ATCC 25922 and Saccharomyces cerevisiae IMR-R-L 962 in grapefruit [Citrus paradisi (Macf.)] juice by UV-C light: changes in bioactive compounds and quality characteristics [PDF]

, 2018
The viability of UV-C treatment (0.0-2.36 J/cm²) at 254 nm as a non-thermal preservation process for grapefruit juice on microbial inactivation, the organic acids and individual flavonoids, as well as the quality characteristics (pH, ºBrix, titratable ...
la Cava, Enzo Luciano Marcelo, Sgroppo, Sonia Cecilia   +1 more
core  

Location of chlorogenic acid biosynthesis pathway and polyphenol oxidase genes in a new interspecific anchored linkage map of eggplant [PDF]

, 2014
© Gramazio et al.; licensee BioMed Central. 2014. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and ...
A Bombarely, A Cho, A Concellón, A Frary, A Kumar, A Moglia, A Stàgel, AP Singh, B Menin, BD Whitaker, C Chai, C Coetzer, C Comino, C Comino, C Ma, C Urbany, CM André, CM Rommens, D Chagné, D Kosambi, D Luthria, E Portis, E Portis, E Portis, EC Ramirez, Elena Castillo, F Wu, F Wu, Francisco Javier Herraiz, G Mennella, H Fukuoka, H Fukuoka, Isabel Andújar, J Doyle, J Prohens, J Prohens, J Van Ooijen, Jaime Prohens, JR Stommel, K Shirasawa, K Yamakawa, KV Alheit, L Barchi, L Barchi, L Barchi, L Tran, M Di Guardo, M Doğan, M Jeuken, M Krzywinski, M Murata, M Plazas, M Plazas, Mariola Plazas, MC Daunay, MD Dos Santos, MD Raigón, P Byrne, P Vos, Pietro Gramazio, PM Hanson, R Kofler, R Lo Scalzo, R Niggeweg, R Shi, Rachel S Meyer, RN Lester, S Doganlar, S Doganlar, S Knapp, S Rozen, S Vilanova, Sandra Knapp, Santiago Vilanova, SM Newman, SM Shetty, T Nunome, T Nunome, T Nunome, T Vogt, TA Hall, The Angiosperm Phylogeny Group, TM Fulton, Y Ren, Z Huang   +84 more
core   +1 more source

Quantitative Analysis of Total Flavonoids and Total Phenolic Acids in Thirty Hypericum Taxa [PDF]

Natural Product Communications, 2013
The content of total flavonoids and total phenolic acids in the aerial parts of thirty Hypericum taxa collected over two consecutive seasons was investigated by spectrophotometric methods. All taxa examined contained flavonoids and phenolic acids in different quantities, although the differences between species and year's harvest were not found to be ...
Maleš, Željan, Friščić, Maja, Hazler-Pilepić, Kroata   +2 more
openaire   +3 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Phytochemical and antioxidant screening of some extracts of Juniperus communis L. and Juniperus oxycedrus L.

Czech Journal of Food Sciences, 2019
The content of phytochemicals, total phenolics, total flavonoids and antioxidant potential of extracts of Juniperus communis L. and Juniperus oxycedrus L. berries were determined.
Nebojša Živić, Slaviša Milošević, Vidoslav Dekić, Biljana Dekić, Novica Ristić, Milenko Ristić, Ljiljana Sretić   +6 more
doaj   +1 more source