Results 91 to 100 of about 135,234 (291)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Content of total polar compounds in previously used cooking oils most marketed in Medellin (Colombia) [PDF]

, 2012
: Concentration of polar compounds in cooking oils is an indicator of high temperatures damage and health risks. However, for some oils, the increase of those compounds is due to beneficial health substances.
Ramírez Botero, Claudia María, Suaterna Hurtado, Adriana Cecilia, Rojano, Benjamín Alberto, Martínez Galán, Julián Paul, Cardona Zuleta, Luz Margarita, Gómez Ramírez, Briana Davahiva   +5 more
core  

Development of a rapid method to determine phenolic and other polar compounds in walnut by capillary electrophoresis–electrospray ionization time-of-flight mass spectrometry

, 2008
The aim of this work was to develop a capillary electrophoresis–mass spectrometry (CE–MS) method to identify and quantify phenolic and other related polar compounds in walnut samples.
CABONI, MARIA, A. M. Gómez Caravaca, VERARDO, VITO, A. Segura Carretero, A. Fernández Gutiérrez   +4 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Reverse osmosis separation of polar organic compounds in aqueous solution

, 1976
The reverse osmosis separation of polar organic compounds from water was examined. A total of 12 different reverse osmosis membranes were tested with 13 polar low-molecular-weight organic compounds consisting of various functional groups.
Chian, ESK, Fang, HHP
core  

Comparison of Domestic and Foreign Safety Standards for Edible Vegetable Oils（Ⅱ） ——Physicochemical Indicators

Liang you shipin ke-ji
This article systematically compared the differences in physicochemical indicators such as acid value, peroxide value, solvent residue, free gossypol, and frying oil discard points between China and international organizations, countries and regions such
ZHAO Chen-wei, JIN Qing-zhe, WANG Xing-guo   +2 more
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Volatile Profiling of Aromatic Traditional Medicinal Plant, Polygonum minus in Different Tissues and Its Biological Activities

Molecules, 2014
The aim of this research was to identify the volatile metabolites produced in different organs (leaves, stem and roots) of Polygonum minus, an important essential oil producing crop in Malaysia.
Rafidah Ahmad, Syarul Nataqain Baharum, Hamidun Bunawan, Minki Lee, Normah Mohd Noor, Emelda Roseleena Rohani, Norashikin Ilias, Noraziah Mohamad Zin   +7 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Valorization of Raw Rice Husk for Total Dissolved Solids (TDS) Adsorption: Kinetic Study and the Effect of Compound Polarity

Asian Journal of Chemical Sciences
Aims: The present study aims to investigate the retention of TDS by adsorption on rice husk, a very abundant adsorbent, available at all times and less expensive. Study Design: This study was conducted by using batch method in the treatment of wastewater and drinking water using adsorption chemistry.
Nombamba Ouéda, Joseph M. Makaya, Mahamadi Nikiema   +2 more
openaire   +1 more source