Results 141 to 150 of about 730,259 (221)
GLP‐1 receptor agonists and serious adverse events: Evidence, uncertainty and clinical implications
Journal of Internal Medicine, EarlyView.Abstract Glucagon‐like peptide‐1 (GLP‐1) receptor agonists provide benefits in weight reduction, glycaemic control in Type 2 diabetes, and cardiovascular and renal outcomes. Their widespread use has given rise to concerns regarding rare but potentially serious adverse events.
Peter Ueda
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney +4 more
wiley +1 more source
Leber hereditary optic neuropathy mutations and toxic‐genetic optic neuropathy — Authors' response [PDF]
Acta Ophthalmologica, 2013 Remes Anne +4 more
openaire +2 more sources
The Journal of Physiology, EarlyView.Abstract figure legend Arboviruses induce virus‐specific alterations in placental structure and functional markers. Chikungunya virus (CHIKV) exposure was associated with reduced syncytiotrophoblast and syncytial knot areas, increased cytotrophoblast proliferation (Ki‐67) and thyroid transporter (MCT8) expression, reduced protective (P‐gp and BCRP ...
Cherley B. V. Andrade +13 more
wiley +1 more source
Schwann Cell‐Specific ATG7‐Dependent Autophagy Protects Myelin in a Mouse Model of Krabbe Disease
Glia, Volume 74, Issue 12, December 2026.Krabbe disease (KD) is caused by mutations in GALC and deregulated lysosomal function in Schwann cells (SCs). Using a SC‐specific Galc‐cKO mouse, we identified altered autophagy in SCs during KD progression. Further ablation of Atg7 in SCs of KD worsened disease severity.
Narayan Dhimal +8 more
wiley +1 more source
The scourge of ethambutol-related toxic optic neuropathy in the Philippines
Philippine Journal of Ophthalmology, 2010
Richard C. Kho, MD
doaj
Head &Neck, Volume 48, Issue 11, Page 3152-3172, November 2026.ABSTRACT Background Supportive care needs of patients receiving immune checkpoint inhibitors (ICIs) for head and neck squamous cell carcinoma (HNSCC) are ill‐defined. Hence, known treatment‐related adverse events (TRAEs) and health‐related quality of life (HRQoL) associated with ICI treatment for HNSCC were examined to inform future supportive care ...
N. D. O'Donnell +11 more
wiley +1 more source
, 2019 Summary •Amiodarone optic neuropathy o Amiodarone is an anti-arrhythmic used by cardiology -Amiodarone produces a toxic optic neuropathy that looks similar to non-arteritic anterior ischemic optic neuropathy (NAION) o Differentiating features between ...
Andrew G. Lee, MD; Jason Zehden
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Defining priorities for care among young adults diagnosed with breast cancer
Pediatric, Adolescent &Young Adult Cancer, Volume 1, Issue 1, November 2026.Abstract Introduction Breast cancer is a leading cause of cancer‐related mortality among young adults (YAs) aged 18–39 years. Although the National Comprehensive Cancer Network recommends that YAs be treated at centers with age‐specific expertise, standardized care pathways are lacking.
Caroline Lommer +9 more
wiley +1 more source
Bilateral anterior ischemic optic neuropathy after bilateral neck dissection
, 2010 María J Suárez-Fernández, Antonio Clariana-Martín, Enrique Mencía-Gutiérrez, Esperanza Gutiérrez-Díaz, Teresa Gracia-García-MiguelOphthalmology Department,
María J Suárez-Fernández +3 more
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