Results 191 to 200 of about 15,449 (239)
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Ciprofloxacin‐induced toxic optic neuropathy
Clinical & Experimental Ophthalmology, 2007AbstractA case of bilateral toxic optic neuropathy that developed in the setting of prolonged oral ciprofloxacin use for the treatment of chronic osteomyelitis is described. The patient experienced progressive, bilateral and symmetrical visual loss, central scotomas and loss of colour vision over a 2‐month period.
Nadeeka Samarakoon +2 more
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Cuban Epidemic Optic Neuropathy and its Relationship to Toxic and Hereditary Optic Neuropathy
Seminars in Ophthalmology, 2010The similarities and differences between toxic/nutritional and hereditary optic neuropathy and the pathophysiologic mechanisms that they have in common are described. This is based on data from the epidemic suffered in Cuba in 1992, which affected the optic nerves of many individuals and the experience of the authors in dealing with various toxic optic
Rosaralis, Santiesteban-Freixas +5 more
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Drug-induced toxic optic neuropathy
Vestnik oftal'mologii, 2020Drug-induced optic neuropathy is a group of disorders in which medications cause degeneration of the optic nerve. The true prevalence of drug-induced neuropathy has not been studied, although the percentage of patients who develop optic nerve damage is known for individual medications.
O D, Ostroumova +5 more
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Toxic Optic Neuropathy From Quinine Overdose
Journal of Neuro-Ophthalmology, 2020Abstract: A 45-year-old man presented with longstanding poor vision in both eyes. His medical history was significant for a remote overdose of quinine. After the ingestion, he fell into a coma and on awakening was not able to see light out of both eyes. Several days later, his central vision began to gradually recover and continued to improve
Paul R, Freund +2 more
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Linezolid-associated toxic optic neuropathy
Neurology, 2006The oxazolidinone antimicrobial linezolid is effective against gram-positive bacteria. Although maximal recommended therapy is 28 days, treatment durations greater than this are common. Linezolid may cause reversible optic neuropathy and irreversible peripheral neuropathy after months of treatment.
J C, Rucker +4 more
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Current Opinion in Ophthalmology, 2013
Many causes of toxic optic neuropathy have been described to date and novel causes of toxicity are continuously being added to the current literature. The pathophysiological basis for the toxicity or a direct causal relationship is yet to be determined for many of these agents.
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Many causes of toxic optic neuropathy have been described to date and novel causes of toxicity are continuously being added to the current literature. The pathophysiological basis for the toxicity or a direct causal relationship is yet to be determined for many of these agents.
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Toxic optic neuropathies: an updated review
Acta Ophthalmologica, 2014AbstractToxic optic neuropathy (TON) is caused by the damage to the optic nerve through different toxins, including drugs, metals, organic solvents, methanol and carbon dioxide. A similar clinical picture may also be caused by nutritional deficits, including B vitamins, folic acid and proteins with sulphur‐containing amino acids. This review summarizes
Andrzej, Grzybowski +3 more
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Ethambutol/Linezolid Toxic Optic Neuropathy
Optometry and Vision Science, 2016To report a rare toxic optic neuropathy after long-term use of two medications: ethambutol and linezolid.A 65-year-old man presented to the Miami Veterans Affairs Medical Center in December 2014 for evaluation of progressive vision decrease in both eyes.
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Toluene Related Toxic Optic Neuropathy
Neuro-Ophthalmology, 2009ABSTRACTToxic optic neuropathy presenting as bilateral painless visual loss causing central or caecocentral scotoma has a wide differential diagnosis. In this report, we present a rare cause of toxic optic neuropathy presenting as almost indistinct optic disc margins in both eyes in a 30-year old man with blurred vision and difficulty in walking and in
Fatih C. Gundogan +5 more
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Toxic-Metabolic and Hereditary Optic Neuropathies
Continuum, 2019The diagnosis of visual loss from toxic-metabolic and hereditary optic neuropathies may be delayed in some cases because of a failure to elicit important information in the clinical history or to recognize typical examination findings. An understanding of the features specific to each type of toxic-metabolic and hereditary optic neuropathy, and of the ...
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