Results 181 to 190 of about 730,259 (221)

Toluene Related Toxic Optic Neuropathy

Neuro-Ophthalmology, 2009
ABSTRACTToxic optic neuropathy presenting as bilateral painless visual loss causing central or caecocentral scotoma has a wide differential diagnosis. In this report, we present a rare cause of toxic optic neuropathy presenting as almost indistinct optic disc margins in both eyes in a 30-year old man with blurred vision and difficulty in walking and in
Güngör Sobacı, Gungor Sabaci, Gungor Sobaci, Fatih C Gündoğan   +1 more
exaly   +2 more sources

Incidence of toxic optic neuropathy with low-dose ethambutol

International Journal of Tuberculosis and Lung Disease, 2016
OBJECTIVE: To investigate the incidence of ethambutol (EMB) induced optic neuropathy prescribed at a relatively low dose of <= 15 mg/kg/day for the treatment of tuberculosis (TB) or Mycobacterium avium complex (MAC) lung disease.
Jeong-Hoon Lee, J-M Hwang, H K Yang
exaly   +2 more sources

Drug-induced toxic optic neuropathy

Vestnik oftal'mologii, 2020
Drug-induced optic neuropathy is a group of disorders in which medications cause degeneration of the optic nerve. The true prevalence of drug-induced neuropathy has not been studied, although the percentage of patients who develop optic nerve damage is known for individual medications.
O D, Ostroumova, E V, Chikh, E V, Rebrova, A Y, Ryazanova, G Sh, Arzhimatova, L K, Moshetova   +5 more
openaire   +2 more sources

Linezolid-associated toxic optic neuropathy

Neurology, 2006
The oxazolidinone antimicrobial linezolid is effective against gram-positive bacteria. Although maximal recommended therapy is 28 days, treatment durations greater than this are common. Linezolid may cause reversible optic neuropathy and irreversible peripheral neuropathy after months of treatment.
J C, Rucker, S R, Hamilton, D, Bardenstein, C M, Isada, M S, Lee   +4 more
openaire   +2 more sources

Toxic optic neuropathies

Current Opinion in Ophthalmology, 2013
Many causes of toxic optic neuropathy have been described to date and novel causes of toxicity are continuously being added to the current literature. The pathophysiological basis for the toxicity or a direct causal relationship is yet to be determined for many of these agents.
openaire   +2 more sources

Toxic optic neuropathies: an updated review

Acta Ophthalmologica, 2014
AbstractToxic optic neuropathy (TON) is caused by the damage to the optic nerve through different toxins, including drugs, metals, organic solvents, methanol and carbon dioxide. A similar clinical picture may also be caused by nutritional deficits, including B vitamins, folic acid and proteins with sulphur‐containing amino acids. This review summarizes
Andrzej, Grzybowski, Magdalena, Zülsdorff, Helmut, Wilhelm, Felix, Tonagel   +3 more
openaire   +2 more sources

Toxic Optic Neuropathy From Quinine Overdose

Journal of Neuro-Ophthalmology, 2020
Abstract: A 45-year-old man presented with longstanding poor vision in both eyes. His medical history was significant for a remote overdose of quinine. After the ingestion, he fell into a coma and on awakening was not able to see light out of both eyes. Several days later, his central vision began to gradually recover and continued to improve
Paul R, Freund, Tom, Wright, Edward A, Margolin   +2 more
openaire   +2 more sources

Toxic-Metabolic and Hereditary Optic Neuropathies

Continuum, 2019
The diagnosis of visual loss from toxic-metabolic and hereditary optic neuropathies may be delayed in some cases because of a failure to elicit important information in the clinical history or to recognize typical examination findings. An understanding of the features specific to each type of toxic-metabolic and hereditary optic neuropathy, and of the ...
openaire   +2 more sources

Toxic medications in Leber's hereditary optic neuropathy

Mitochondrion, 2019
Leber's hereditary optic neuropathy (LHON) is a maternally inherited mitochondrial disorder characterized by acute bilateral vision loss. The pathophysiology involves reactive oxygen species (ROS), which can be affected by medications. This article reviews the evidence for medications with demonstrated and theoretical effects on mitochondrial function,
Kaitlin, Kogachi, Anna, Ter-Zakarian, Samuel, Asanad, Alfredo, Sadun, Rustum, Karanjia   +4 more
openaire   +2 more sources

Ethambutol/Linezolid Toxic Optic Neuropathy

Optometry and Vision Science, 2016
ABSTRACT Purpose To report a rare toxic optic neuropathy after long‐term use of two medications: ethambutol and linezolid. Case Report A 65‐year‐old man presented to the Miami Veterans Affairs Medical Center in ...
openaire   +2 more sources