Results 251 to 260 of about 16,960 (297)

Toxic Shock Syndrome Toxin 1 Contributes to the Arthritogenicity of Staphylococcus aureus

Journal of Infectious Diseases, 1994
Although enterotoxins have been implicated in disease states such as food poisoning and toxic shock syndrome, their role in infectious arthritis is not known. To study the arthritogenic properties of toxic shock syndrome toxin 1 (TSST-1), two pairs of S.
A, Abdelnour, T, Bremell, A, Tarkowski
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Toxic shock syndrome toxin-1-induced death is prevented by CTLA4Ig

The Journal of Immunology, 1996
Abstract Lethal toxic shock syndrome (TSS) results from the MHC class II presentation of bacterial superantigens, most commonly toxic shock syndrome-1 (TSST-1), to specific TCR Vbeta-bearing T cells. This superantigen-induced stimulation of whole T cell subsets leads to the exuberant cytokine production that in turn causes the shock ...
B, Saha, B, Jaklic, D M, Harlan, G S, Gray, C H, June, R, Abe   +5 more
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The role of toxic shock syndrome toxin-1 in the pathogenesis of toxic shock syndrome

2010
Toxic shock syndrome toxin-1 (TSST-1), an exoprotein produced by some strains of Staphylococcus aureus, is implicated in the pathogenesis of menstrual TSS. However, its role in nonmenstrual TSS is less certain. In order to study the pathogenetic role of TSST-1 in TSS, three approaches were taken: a) to develop an ELISA for detection of TSST-1 in ...
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Effect of Tampon Wraps on Production of Toxic Shock Syndrome Toxin 1

Clinical Infectious Diseases, 1989
The influence of tampon wraps on the production and distribution of toxic shock syndrome toxin 1 (TSST-1) was investigated with use of a disk-membrane-agar method. Filter membranes (45 micron) overlaying agar medium in 50-mm petri dishes were spread-inoculated with a TSST-1-producing strain of Staphylococcus aureus and covered with 0.5 mL of whole ...
R N, Robbins, B J, Kelly, G L, Hehl, M S, Bergdoll   +3 more
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Effect of Magnesium on in Vitro Production of Toxic Shock Syndrome Toxin 1

Clinical Infectious Diseases, 1989
Batch and chemostat culture of Staphylococcus aureus strain S411 was conducted in an investigation of the role of Mg++ in the control of production of toxic shock syndrome toxin 1 (TSST-1). Under both growth conditions, Mg++ influenced bacterial growth, and TSST-1 production was correlated with bacterial growth.
J F, James, M C, Chu, L, Lee, S A, Peck, C, McKissick, H, Sullivan, K, Frogner, M, Melish   +7 more
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Effect of toxic shock syndrome toxin-1 on human hemostatic parameters

Thrombosis Research, 1989
The effect of toxic-shock-syndrome-toxin-1 (TSST-1) on coagulation and platelet aggregation was studied in blood samples from human healthy volunteers. TSST-1 at 5 micrograms/ml does not modify the extrinsic or intrinsic coagulation pathways. However, thrombin clotting time (TCT) was significantly increased in the presence of TSST-1.
R, Gareau, J, Gruda, V V, Micusan
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Staphylococcal toxic shock syndrome toxin-1 inhibits monocyte apoptosis

Journal of Allergy and Clinical Immunology, 1999
Chronic atopic dermatitis (AD) lesions are associated with colonization by exotoxin-producing Staphylococcus aureus. Evidence suggests that cytokine production in AD, particularly of GM-CSF, prolongs survival of both peripheral blood monocytes and dermal monocyte-macrophages, the predominate inflammatory cell in lesions caused by chronic AD.We sought ...
D L, Bratton, K R, May, J M, Kailey, D E, Doherty, D Y, Leung   +4 more
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Growth and analysis of crystal forms of toxic shock syndrome toxin 1

Proteins: Structure, Function, and Bioinformatics, 1993
AbstractNative toxic shock syndrom toxin 1 (TSST‐1) purified from Staphylococcus aurius has been crystallized in four different forms. The highest resolution data (2.05 Å) was collected from orthorhombic crystals belonging to the space group C2221. The unit cell dimension are a = 108.7 Å, b = 177.5 Å, c = 97.6 Å. Rotation function analysis of this from
C A, Earhart, G S, Prasad, D L, Murray, R P, Novick, P M, Schlievert, D H, Ohlendorf   +5 more
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Toxic Shock Syndrome Caused by a Strain of Staphylococcus aureus That Produces Enterotoxin C but Not Toxic Shock Syndrome Toxin-1

Archives of Pediatrics & Adolescent Medicine, 1989
An 8-month-old infant presented with pneumonia and pleural effusion associated with clinical manifestation of toxic shock syndrome. A Staphylococcus aureus strain isolated from the pleural fluid produced enterotoxin C, but not toxic shock syndrome toxin-1 or other enterotoxins.
M F, Rizkallah, A, Tolaymat, J S, Martinez, P M, Schlievert, E M, Ayoub   +4 more
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Risk of Developing Toxic Shock Syndrome Associated with Toxic Shock Syndrome Toxin 1 Following Nongenital Staphylococcal Infection

Clinical Infectious Diseases, 1989
Few risk factors for nonmenstrual toxic shock syndrome (TSS) have been identified. This study sought to determine at what rate and under what circumstances nongenital toxigenic Staphylococcus aureus infections led to TSS. Clinical isolates of S. aureus were examined for the production of TSS toxin 1 (TSST-1), and available sera from infected patients ...
J A, Jacobson, E, Kasworm, J A, Daly
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