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Distribution and Expression of Toxic Shock Syndrome Toxin 1 Gene Among Staphylococcus aureus Isolates of Toxic Shock Syndrome and Non-Toxic Shock Syndrome Origin

Clinical Infectious Diseases, 1989
Toxic shock syndrome toxin 1 (TSST-1), plays a significant role in the pathogenesis of TSS. TSST-1 production is subject to physiologic and environmental constraints. Thus, DNA probes that detect the chromosomal gene encoding the toxin are of value diagnostically, epidemiologically, and for studies of gene expression.
P F, Bonventre   +3 more
openaire   +2 more sources

Toxicity of Staphylococcal Toxic Shock Syndrome Toxin 1 for Germ-Free and Conventional Piglets

Clinical Infectious Diseases, 1989
The susceptibilities of conventional and germ-free miniature pigs to staphylococcal toxic shock syndrome toxin 1 (TSST-1) were studied and compared. TSST-1 at doses of 100 micrograms/kg evoked reactions similar to those observed in rabbits, i.e., hyperthermia, diarrhea, apathy, conjunctival hyperemia, and various changes indicating toxic damage of ...
M, Bulanda   +8 more
openaire   +2 more sources

Toxic shock syndrome Staphylococcus aureus: effect of tampons on toxic shock syndrome toxin 1 production.

Obstetrics and gynecology, 1984
Tampons were tested for effect on growth and production of toxic shock syndrome toxin 1 by Staphylococcus aureus. Under good growth conditions, regular absorbency tampons had little effect on bacterial growth and inhibited toxin production two- to fourfold.
P M, Schlievert   +2 more
openaire   +1 more source

The role of toxic shock syndrome Toxin-1 and Staphylococcal Enterotoxin A in the pathogenesis of toxic shock syndrome

2008
Toxic shock syndrome (TSS) is a multisystem disease associated with S. aureus infection. Toxic shock syndrometoxin-1 (TSST-1) is implicated in the majority but not all cases. We have previously demonstrated that sero \conversion to staphylococcal enterotoxin A (SEA) is also more prevalent in TSS than in non-TSS cases, suggesting its possible role in ...
openaire   +1 more source

Effect of Trace Metals on the Synthesis of Toxic Shock Syndrome Toxin 1

Clinical Infectious Diseases, 1989
The effect of 10 trace metals on the production of toxic shock syndrome toxin 1 (TSST-1) was studied in a metal-deficient chemically defined medium (CDM) with toxic shock syndrome (TSS) and non-TSS strains of Staphylococcus aureus. When individual metals were tested, only Mg++ stimulated cell growth and TSST-1 production. TSST-1 yield was responsive to
openaire   +2 more sources

Toxic Shock Syndrome Toxin 1 Resistance in Mice is Related to Interleukin 1 Production by Toxic Shock Syndrome Toxin 1

Clinical Infectious Diseases, 1989
T. Ikejima   +3 more
openaire   +1 more source

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