Results 51 to 60 of about 16,960 (297)

Enterotoxigenic Potential of Coagulase-Negative Staphylococci from Ready-to-Eat Food

Pathogens, 2020
Although coagulase-positive staphylococci are considered to be the main factor responsible for food poisoning, an increasing role for the coagulase-negative staphylococci in the production of enterotoxins has been observed in recent years. This study was
Wioleta Chajęcka-Wierzchowska, Joanna Gajewska, Patryk Wiśniewski, Anna Zadernowska   +3 more
doaj   +1 more source

Localization of biologically important regions on toxic shock syndrome toxin 1 [PDF]

Infection and Immunity, 1996
Toxic shock syndrome toxin 1 (TSST-1) contains a long central alpha helix that forms the base of two grooves on opposite sides of the molecule. Previous studies indicated that residues 132, 135, and 140 along the back of the central alpha helix are important in the biological activities.
D L, Murray, C A, Earhart, D T, Mitchell, D H, Ohlendorf, R P, Novick, P M, Schlievert   +5 more
openaire   +2 more sources

Frequency of the toxic shock syndrome toxin-1 gene in methicillin-susceptible and -resistant Staphylococcus aureus isolates from teaching hospitals in Shiraz, Iran

Revista da Sociedade Brasileira de Medicina Tropical, 2015
INTRODUCTION: Staphylococcus aureus produces a range of virulence factors such as toxic shock syndrome toxin-1. METHODS: In this cross-sectional study of 345 clinical S.
Mohammad Motamedifar, Hadi Sedigh Ebrahim-Saraie, Seyedeh Mahsan Hoseini Alfatemi, Mehrdad Zalipour, Mohammad Kaveh, Hossein Khoshkharam-Roodmajani   +5 more
doaj   +1 more source

Group B Streptococcal Toxic Shock Syndrome and covR/S Mutations Revisited [PDF]

, 2017
Gene mutations in the virulence regulator CovR/S of group A Streptococcus play a substantial role in the pathogenesis of streptococcal toxic shock syndrome.
Brandt, Claudia M, Muad Abd el Hay, Parham Sendi, Barbara Spellerberg, Sendi, Parham, Spellerberg, Barbara, Claudia M. Brandt, El Hay, Muad Abd   +7 more
core   +1 more source

Produção de enterotoxinas e da toxina da síndrome do choque tóxico por cepas de Staphylococcus aureus isoladas na mastite bovina Production of enterotoxins and toxic shock syndrome toxin by Staphylococcus aureus strains isolated from bovine mastitis

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2007
A total of 72 strains of Staphylococcus aureus were examined for the production of staphylococcal enterotoxins (SE) A, B, C, D and toxic shock syndrome toxin (TSST-1).
A. Nader Filho, L.M. Ferreira, L.A. Amaral, O.D. Rossi Junior, R.P. Oliveira   +4 more
doaj   +1 more source

Nonproduction of toxic shock syndrome toxin 1 by coagulase-negative staphylococci [PDF]

Journal of Clinical Microbiology, 1987
We tested 187 strains of coagulase-negative staphylococci (CNS) for the production of toxic shock syndrome toxin 1 (TSST-1). A total of 111 CNS strains were isolated from the tampons of menstruating women and 74 were isolated from unused tampons. Two strains were isolated from the genital tract of a patient with toxic shock syndrome.
J, Parsonnet, A E, Harrison, S E, Spencer, A, Reading, K C, Parsonnet, E H, Kass   +5 more
openaire   +2 more sources

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

TSST-1 promotes colonization of Staphylococcus aureus within the vaginal tract by activation of CD8+ T cells

Infection and Immunity
Toxic shock syndrome toxin-1 (TSST-1) is a superantigen produced by Staphylococcus aureus and is the determinant of menstrual toxic shock syndrome (mTSS); however, the impact of TSST-1 on the vaginal environment beyond mTSS is not understood.
Karine Dufresne, Kait F. Al, Heather C. Craig, Charlotte E. M. Coleman, Katherine J. Kasper, Jeremy P. Burton, John K. McCormick   +6 more
doaj   +1 more source

The effect of Staphylococcus aureus carriage in late pregnancy on antibody levels to staphylococcal toxins in cord blood and breast milk. [PDF]

, 2008
We investigated the effect of carriage of Staphylococcus aureus in the later stages of pregnancy on levels of antibody specific to the S. aureus toxins, staphylococcal enterotoxin B (SEB), staphylococcal enterotoxin C (SEC) and toxic shock syndrome toxin-
Morris, James A., Telford, David R., Lauder, Robert M., Harrison, Linda M.   +3 more
core  

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source