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Non-menstrual toxic shock syndrome (non-mTSS) is a life-threatening disease caused by Staphylococcus aureus strains producing superantigens, such as staphylococcal enterotoxins A, B, C, and toxic shock syndrome toxin-1 (TSST-1).
Maniruzzaman (10063182) +17 more
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Intracellular expression of toxic shock syndrome toxin 1 in Saccharomyces cerevisiae [PDF]
In order to search for an occult cytotoxic enzymatic activity of the toxic shock syndrome toxin 1 (TSST-1), we placed the gene encoding TSST-1 (tstH) under the control of an inducible promoter in the eukaryotic yeast Saccharomyces cerevisiae. Under similar circumstances, the known bacterial enzymatic cytotoxins Shiga-like toxin and diphtheria toxin are
R L, Deresiewicz +4 more
openaire +2 more sources
Non-menstrual toxic shock syndrome (non-mTSS) is a life-threatening disease caused by Staphylococcus aureus strains producing superantigens, such as staphylococcal enterotoxins A, B, C, and toxic shock syndrome toxin-1 (TSST-1).
Maniruzzaman (10063182) +17 more
core +1 more source
Monoclonal Antibodies Against Toxic Shock Syndrome Toxin-1 And Their Use In Diagnosis [PDF]
Toxic shock syndrome toxin -1 (TSST-1) is a 22kDa extracellular protein produced by some strains of Staphylococcus aureus. It is implicated in the pathogenesis of toxic shock syndrome, an acute life-threatening multisystem disease.
Elvin, Stephen John
core +1 more source
Non-menstrual toxic shock syndrome (non-mTSS) is a life-threatening disease caused by Staphylococcus aureus strains producing superantigens, such as staphylococcal enterotoxins A, B, C, and toxic shock syndrome toxin-1 (TSST-1).
Maniruzzaman (10063182) +17 more
core +1 more source
We report a SCCmec II, ST39 methicillin-resistant Staphylococcus aureus isolate from pigs that harboured toxic-shock syndrome toxin gene (tsst-1). The gene was located in a rare pathogenicity island SaPI68111, which also carried enterotoxin genes that ...
Dulmini Nanayakkara Sapugahawatte +5 more
doaj +1 more source
Human scFvs That Counteract Bioactivities of Staphylococcus aureus TSST-1
Some Staphylococcus aureus isolates produced toxic shock syndrome toxin-1 (TSST-1) which is a pyrogenic toxin superantigen (PTSAg). The toxin activates a large fraction of peripheral blood T lymphocytes causing the cells to proliferate and release ...
Thunchanok Rukkawattanakul +6 more
doaj +1 more source
TSST-1 protein exerts indirect effect on platelet activation and apoptosis
Thrombocytopenia or platelet dysfunction is a risk factor for severe infection. Staphylococcus aureus (S. aureus) releases a variety of virulence factors especially toxic shock syndrome toxin 1 (TSST-1), which may cause toxic shock syndrome. S.
Min Guo +6 more
doaj +1 more source
Interaction of toxin-1 and T lymphocytes in toxic shock syndrome
Toxic shock syndrome (TSS) is a potentially fatal illness caused by infection with the bacterium Staphylococcus aureus. TSS toxin-1 (TSST-1) contains a T-cell epitope with specificity for human V-beta-2. Binding of TSST-1 to the human major histocompatibility complex and T cell receptors activates T cells and triggers the secretion of high amounts of ...
Kang, De +8 more
openaire +3 more sources
Expression of toxic shock syndrome toxin-1 gene of Staphylococcus aureus in milk: Proof of concept
The aim of this study was to assess the expression of a toxic shock syndrome toxin-1 (TSST-1) gene of Staphylococcus aureus in different types of milk, depending on inadequate temperature and storage conditions.
Milijana Babić +6 more
doaj +1 more source

