Results 21 to 30 of about 15,154 (159)

Detection of Toxic Shock Syndrome Toxin-1 among Children Undergoing Surgical Operations

مجلة كلية الطب, 2017
Background: Toxic-shock syndrome (TSS) is an acute onset; multiorgan disease caused mainly by Toxic-shock syndrome toxin-1 (TSST-1) producing Staphylococcus aureus strains.Testing for TSST-1 or anti-TSST-1 antibodies in the clinical setting may help to ...
Abdul-Razak Sh. Hasan, Asmaa H. Hwaid, Zainab H. Mahdy   +2 more
doaj   +1 more source

Toxicity of recombinant toxic shock syndrome toxin 1 and mutant toxins produced by Staphylococcus aureus in a rabbit infection model of toxic shock syndrome [PDF]

Infection and Immunity, 1993
Menstrually associated toxic shock syndrome (TSS) is attributed primarily to the effects of staphylococcal exotoxin toxic shock syndrome toxin 1 (TSST-1). A region of the 194-amino-acid toxin spanning residues 115 through 144 constitutes a biologically active site.
P F, Bonventre, H, Heeg, C, Cullen, C J, Lian   +3 more
openaire   +2 more sources

Interaction of Staphylococcal Toxic Shock Syndrome Toxin-1 and Enterotoxin A on T Cell Proliferation and TNFα Secretion in Human Blood Mononuclear Cells

Canadian Journal of Infectious Diseases, 1999
BACKGROUND: The majority of menstrual toxic shock syndrome (MTSS) cases are caused by a single clone of Staphylococcus aureus that produces both toxic shock syndrome toxin-1 (TSST-1) and staphylococcal enterotoxin A (SEA).
Monica L De Boer, Winnie WS Kum, Anthony W Chow   +2 more
doaj   +1 more source

Waterhouse friderichsen syndrome in a case of staphylococcal toxic shock syndrome

Journal of Pediatric Critical Care, 2016
Staphylococcal toxic shock syndrome (TSS) is a rare and potentially fatal multi system dysfunction. The syndrome occurs primarily due to TSS Toxin-1 (TSS-1) liberated by Staphylococcus aureus (SA).
Devdeep Mukherjee, Prabhas Prasun Giri, Suman Poddar   +2 more
doaj   +1 more source

Multiplex PCR for Detection of Exfoliative Toxins, and Toxic Shock Syndrome Toxin 1 Genes in MRSA Strains of Clinical Staphylococcus aureus Isolates

Tikrit Journal of Pure Science, 2023
This research approaches to investigate toxin gene content of the methicillin resistant Staphylococcus aureus strains that are clinically collected from human skin infection cases by performing multiplex polymerase chain reaction (PCR) technique ...
Suha M. Abed, Waad M. Raoof, Akeel H. A. Assie, Eman N. I. Al-Jaafari, Yasmeen A. Hadi   +4 more
doaj   +1 more source

A rabbit model of toxic shock syndrome that uses a constant, subcutaneous infusion of toxic shock syndrome toxin 1 [PDF]

Infection and Immunity, 1987
We have developed a rabbit model of toxic shock syndrome that uses a subcutaneous infusion pump to administer toxic shock syndrome toxin 1 (TSST-1). A dose of 150 micrograms, infused at a constant rate over a period of 7 days, resulted in a characteristic illness highlighted by fever, conjunctival hyperemia, cachexia, and lethargy.
J, Parsonnet, Z A, Gillis, A G, Richter, G B, Pier   +3 more
openaire   +2 more sources

Intracellular expression of toxic shock syndrome toxin 1 in Saccharomyces cerevisiae [PDF]

Infection and Immunity, 1994
In order to search for an occult cytotoxic enzymatic activity of the toxic shock syndrome toxin 1 (TSST-1), we placed the gene encoding TSST-1 (tstH) under the control of an inducible promoter in the eukaryotic yeast Saccharomyces cerevisiae. Under similar circumstances, the known bacterial enzymatic cytotoxins Shiga-like toxin and diphtheria toxin are
R L, Deresiewicz, J A, Flaxenburg, M, Chan, R W, Finberg, D L, Kasper   +4 more
openaire   +2 more sources

Swine methicillin-resistant Staphylococcus aureus carrying toxic-shock syndrome toxin gene in Hong Kong, China

Emerging Microbes and Infections, 2020
We report a SCCmec II, ST39 methicillin-resistant Staphylococcus aureus isolate from pigs that harboured toxic-shock syndrome toxin gene (tsst-1). The gene was located in a rare pathogenicity island SaPI68111, which also carried enterotoxin genes that ...
Dulmini Nanayakkara Sapugahawatte, Carmen Li, Yun Kit Yeoh, Priyanga Dharmaratne, Chendi Zhu, Margaret Ip   +5 more
doaj   +1 more source

Human scFvs That Counteract Bioactivities of Staphylococcus aureus TSST-1

Toxins, 2017
Some Staphylococcus aureus isolates produced toxic shock syndrome toxin-1 (TSST-1) which is a pyrogenic toxin superantigen (PTSAg). The toxin activates a large fraction of peripheral blood T lymphocytes causing the cells to proliferate and release ...
Thunchanok Rukkawattanakul, Nitat Sookrung, Watee Seesuay, Nattawat Onlamoon, Pornphan Diraphat, Wanpen Chaicumpa, Nitaya Indrawattana   +6 more
doaj   +1 more source

TSST-1 protein exerts indirect effect on platelet activation and apoptosis

Platelets, 2022
Thrombocytopenia or platelet dysfunction is a risk factor for severe infection. Staphylococcus aureus (S. aureus) releases a variety of virulence factors especially toxic shock syndrome toxin 1 (TSST-1), which may cause toxic shock syndrome. S.
Min Guo, Tiantian Yi, Qian Wang, Daqing Wang, Ping Feng, Dai Kesheng, He Chunyan   +6 more
doaj   +1 more source