Results 31 to 40 of about 15,154 (159)
Interaction of toxin-1 and T lymphocytes in toxic shock syndrome
Frontiers in Bioscience, 2014 Toxic shock syndrome (TSS) is a potentially fatal illness caused by infection with the bacterium Staphylococcus aureus. TSS toxin-1 (TSST-1) contains a T-cell epitope with specificity for human V-beta-2. Binding of TSST-1 to the human major histocompatibility complex and T cell receptors activates T cells and triggers the secretion of high amounts of ...
Kang, De +8 more
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Expression of toxic shock syndrome toxin-1 gene of Staphylococcus aureus in milk: Proof of concept
Mljekarstvo, 2018 The aim of this study was to assess the expression of a toxic shock syndrome toxin-1 (TSST-1) gene of Staphylococcus aureus in different types of milk, depending on inadequate temperature and storage conditions.
Milijana Babić +6 more
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Enterotoxigenic Potential of Coagulase-Negative Staphylococci from Ready-to-Eat Food
Pathogens, 2020 Although coagulase-positive staphylococci are considered to be the main factor responsible for food poisoning, an increasing role for the coagulase-negative staphylococci in the production of enterotoxins has been observed in recent years. This study was
Wioleta Chajęcka-Wierzchowska +3 more
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Toxic shock syndrome toxin-1, not α-toxin, mediated Bundaberg fatalities
Microbiology, 2015 The 1928 Bundaberg disaster is one of the greatest vaccine tragedies in history. Of 21 children immunized with a diphtheria toxin-antitoxin preparation contaminated with Staphylococcus aureus, 18 developed life-threatening disease and 12 died within 48 h. Historically, the deaths have been attributed to α-toxin, a secreted cytotoxin produced by most S.
Elizabeth A, Mueller +2 more
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Revista da Sociedade Brasileira de Medicina Tropical, 2015 INTRODUCTION: Staphylococcus aureus produces a range of virulence factors such as toxic shock syndrome toxin-1. METHODS: In this cross-sectional study of 345 clinical S.
Mohammad Motamedifar +5 more
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Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2007 A total of 72 strains of Staphylococcus aureus were examined for the production of staphylococcal enterotoxins (SE) A, B, C, D and toxic shock syndrome toxin (TSST-1).
A. Nader Filho +4 more
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Nihon Naika Gakkai Zasshi, 1988 患者は55才の男性でショック状態で入院となった.入院時の体温は41°Cで脈拍は触知せず,眼瞼結膜の充血著明で躯幹の紅皮症,上腹部圧痛および筋痛がみられた.検査所見は急激な重症感染症,腎不全,筋障害,肝障害を示唆した.敗血症性ショックを疑い血液培養,尿培養,便培養,髄液培養,咽頭培養を頻回に行なったが全て陰性であった.抗生物質,コルチコステロイド,ドーパミン,ドブタミン,ノルアドレナリン等の薬物投与により,患者は回復し約1カ月の経過で後遺症を残さず退院した.症状および検査所見から本例はtoxic shock syndrome (TSS)の診断基準を十分に満足した.また血中よりTSST-1をRPLA法で証明した.診断基準を満足し,ブドウ球菌は培養にて陰性で,かつ血中より直接TSST ...
MIHARA, Junji +7 more
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Localization of biologically important regions on toxic shock syndrome toxin 1 [PDF]
Infection and Immunity, 1996 Toxic shock syndrome toxin 1 (TSST-1) contains a long central alpha helix that forms the base of two grooves on opposite sides of the molecule. Previous studies indicated that residues 132, 135, and 140 along the back of the central alpha helix are important in the biological activities.
D L, Murray +5 more
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Infection and ImmunityToxic shock syndrome toxin-1 (TSST-1) is a superantigen produced by Staphylococcus aureus and is the determinant of menstrual toxic shock syndrome (mTSS); however, the impact of TSST-1 on the vaginal environment beyond mTSS is not understood.
Karine Dufresne +6 more
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Epithelial proinflammatory response and curcumin-mediated protection from staphylococcal toxic shock syndrome toxin-1. [PDF]
PLoS ONE, 2012 Staphylococcus aureus initiates infections and produces virulence factors, including superantigens (SAgs), at mucosal surfaces. The SAg, Toxic Shock Syndrome Toxin-1 (TSST-1) induces cytokine secretion from epithelial cells, antigen presenting cells ...
Matthew M Schaefers +8 more
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