Results 11 to 20 of about 4,361 (182)

Optimization of Ethanol Extraction Technology for Yujin Powder Using Response Surface Methodology with a Box–Behnken Design Based on Analytic Hierarchy Process–Criteria Importance through Intercriteria Correlation Weight Analysis and Its Safety Evaluation

open access: yesMolecules, 2023
Here, we aimed to optimize the ethanol extraction technology for Yujin powder (YJP) and evaluate its safety. The ultrasonic-assisted ethanol reflux extraction method refluxing was used to extract YJP.
Lidong Jiang   +10 more
doaj   +1 more source

Hematological Parameters in Subchronic Toxicity Test of Black Garlic Ethanol Extract in Rats [PDF]

open access: yesJournal of Fundamental and Applied Pharmaceutical Science, 2022
The community has used black garlic since ancient times for hypercholesterolemic. Until now, people still consume both raw and cooked black garlic. Black garlic is included in processed garlic products. People on the Asian continent have used black garlic for the past 10 years.
Ellen Stephanie Rumaseuw   +2 more
openaire   +2 more sources

Edible Safety Assessment of Genetically Modified Rice T1C-1 for Sprague Dawley Rats through Horizontal Gene Transfer, Allergenicity and Intestinal Microbiota. [PDF]

open access: yesPLoS ONE, 2016
In this study, assessment of the safety of transgenic rice T1C-1 expressing Cry1C was carried out by: (1) studying horizontal gene transfer (HGT) in Sprague Dawley rats fed transgenic rice for 90 d; (2) examining the effect of Cry1C protein in vitro on ...
Kai Zhao   +14 more
doaj   +1 more source

A NEW FATHEAD MINNOW (PIMEPHALES PROMELAS) SUBCHRONIC TOXICITY TEST [PDF]

open access: yesEnvironmental Toxicology and Chemistry, 1985
Abstract The most commonly used test for evaluating the toxicity of effluents to fish and invertebrates has been the acute lethality test. However, effluents frequently are not acutely toxic, and so assessing the sublethal effects on fish and invertebrates is important.
Teresa J. Norberg, Donald I. Mount
openaire   +1 more source

In vivo toxicity evaluation of a standardized extract of Syzygium aqueum leaf

open access: yesToxicology Reports, 2014
In this study, the acute and subchronic toxicity effect of the Syzygium aqueum leaf extract (SA) was evaluated. For the acute toxicity study, a single dose of 2000 mg/kg of the SA was given by oral-gavage to male Sprague-Dawley (SD) rats.
Thamilvaani Manaharan   +3 more
doaj   +1 more source

Three month inhalation exposure to low-level PM2.5 induced brain toxicity in an Alzheimer's disease mouse model.

open access: yesPLoS ONE, 2021
Although numerous epidemiological studies revealed an association between ambient fine particulate matter (PM2.5) exposure and Alzheimer's disease (AD), the PM2.5-induced neuron toxicity and associated mechanisms were not fully elucidated.
Sheng-Han Lee   +13 more
doaj   +1 more source

Acute, subchronic toxicity and genotoxicity studies of JointAlive, a traditional Chinese medicine formulation for knee osteoarthritis.

open access: yesPLoS ONE, 2023
AimIn vivo and in vitro toxicity tests of JointAlive® were studied in animal models to support the safe use of JointAlive® as a drug for knee osteoarthritis treatment.MethodsThe acute toxicity study in Sprague Dawley (SD) rats was conducted at a 20 g/kg ...
Yuanyuan Wang   +8 more
doaj   +1 more source

Subacute and subchronic oral toxicity assessments of Acridocarpus smeathmannii (DC.) Guill. & Perr. root in Wistar rats

open access: yesToxicology Reports, 2019
Recent adverse herb reactions have stimulated interest documenting the safety profile of medicinal agents. Thus, subacute and subchronic oral toxicity of the hydroethanolic extract of Acridocarpus smeathmannii root (HEASR) in Wistar rats was investigated.
O.E. Kale, O. Awodele, A.J. Akindele
doaj   +1 more source

STUDY OF PHARMACOLOGICAL ACTIVITY OF NIGELLA DAMASCENA FIXED OIL IN EXPERIMENT [PDF]

open access: yesResearch Results in Pharmacology, 2017
Introduction: Literature data, rich chemical macro-microelement composition set the stage for experimental pharmacological study of adaptogene and lipid protective activity of Nigella damascena essential oil. Objectives: study of pharmacological activity
Marina Efremova   +2 more
doaj   +3 more sources

Hepatotoxicity and subchronic toxicity tests of Morinda citrifolia (noni) fruit

open access: yesThe Journal of Toxicological Sciences, 2009
Morinda citrifolia (noni) fruit juice has been approved as a safe food in many nations. A few cases of hepatitis in people who had been drinking noni juice have been reported, even though no causal link could be established between the liver injury and ingestion of the juice.
Brett J., West   +2 more
openaire   +3 more sources

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