Results 131 to 140 of about 160,346 (305)
Advanced Science, EarlyView.In this study, a MXene‐based V4C3 nanoplatform, VARH, was constructed, which achieved a photothermal conversion efficiency of 44.21% in the NIR‐II window. This platform integrated photothermal therapy, chemodynamic therapy, and thermodynamic therapy with CRISPR/Cas9‐mediated heat shock protein 90 knock‐out technology.
Zi‐Jian Huang +8 more
wiley +1 more source
Developing site-specific guidelines for orchard soils based on bioaccessibility – Can it be done? [PDF]
, 2008 Horticultural land within the periurban fringe of NZ towns and cities increasingly is being developed for residential subdivision. Recent surveys have shown that concentrations of As, Cd, Cu, Pb, and ΣDDT (sum of DDT and its degradation products DDE and ...
Gaw, Sally K. +4 more
core
Highly Biomimetic Ectodermal Epithelial Organoids for Epithelial Barrier Stimulation Assays
Advanced Science, EarlyView.ABSTRACT Evaluating the potential toxicity of pharmaceuticals and biomaterials to ectodermal epithelia, such as the oral mucosa and skin, is indispensable in pre‐clinical assessments. However, this remains a challenge primarily owing to the lack of physiologically relevant and accurate screening models.
Yiming Chen +13 more
wiley +1 more source
Acute Toxicologic Evaluation of Methyltrichlorosilane [PDF]
Journal of the American College of Toxicology, 1993 R. C. Myers, B. Ballantyne
openaire +1 more source
Advanced Science, EarlyView.This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård +19 more
wiley +1 more source
Advanced Science, EarlyView.This study explores the opposing effects of the mGluR2 and mGluR3 receptors on amyloid precursor protein processing. mGluR2 promotes amyloidogenic cleavage, while mGluR3 favors non‐amyloidogenic pathways. Using a brain‐penetrant nanobody as a mGluR2 positive allosteric modulator, the study uncovers how its chronic activation aggravates amyloid‐β burden
Pierre‐André Lafon +21 more
wiley +1 more source
Species Dependent Toxicity Comparison Outcome
Advanced Science, EarlyView.By quantitatively assessing and comparing toxicity responses across different animal species and material compositions, our data reveal that toxicity rankings among different materials may be reversed across species. ABSTRACT Toxicity comparison plays a crucial role in material selection across diverse application fields.
Lian Xiao +7 more
wiley +1 more source
Tracking of [14C]Polystyrene Nanoplastics in Pregnant Mice
Advanced Science, EarlyView.This study investigates [14C]polystyrene nanoplastic ([14C]PS) translocation in late‐stage pregnant mice after intranasal (0.5 mg of [14C]PS on GD12, GD14, and GD16, n = 6) and intravenous administration (1.5 mg of [14C]PS on GD16, n = 6). 14C‐radiolabel allows quantitative tracking of unmodified polystyrene nanoplastics.
Olga Khaybullina +2 more
wiley +1 more source
Toxicological approach to setting spacecraft maximum allowable concentrations for carbon monoxide [PDF]
The Spacecraft Maximum Allowable Concentrations (SMACs) are exposure limits for airborne chemicals used by NASA in spacecraft. The aim of these SMACs is to protect the spacecrew against adverse health effects and performance decrements that would ...
James, J. T., Limero, T. F., Wong, K. L.
core +1 more source
Advanced Science, EarlyView.This study proposes a piezoelectric interface modification strategy to amplify the piezoionic effect. The piezoelectric interface generates an intrinsic electric field, which not only drives rapid ion migration but also concentrates polarized ions on the interface. The flexible sensor delivers superior performance, such as a quick response rate, strong
Yanyu Chen +5 more
wiley +1 more source