Results 61 to 70 of about 839,197 (349)

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

open access: yesFEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti   +8 more
wiley   +1 more source

Green Toxicology: a strategy for sustainable chemical and material development

open access: yesEnvironmental Sciences Europe, 2017
Green Toxicology refers to the application of predictive toxicology in the sustainable development and production of new less harmful materials and chemicals, subsequently reducing waste and exposure.
Sarah E. Crawford   +7 more
doaj   +1 more source

The Concentration of Selected Heavy Metals in Muscles, Liver and Kidneys of Pigs Fed Standard Diets and Diets Containing 60% of New Rye Varieties

open access: yesAnimals, 2021
The carry-over of heavy metals from feed to muscles is generally low if animals are fed with a standard diet containing amounts below the maximum permissible levels.
Agnieszka Chałabis-Mazurek   +8 more
doaj   +1 more source

Environmental toxicology and chemistry (1 November 2017–31 October 2018)

open access: yesEnvironmental Toxicology and Chemistry, 2019
We exposed zebrafish (Danio rerio) to different concentrations of lead and cadmium, and monitored them for survival at 24, 48, 72, and 96 h. Metal toxicity was predicted and compared using the dose–response and general threshold survival models in terms ...
An He   +5 more
semanticscholar   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

open access: yesFEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama   +7 more
wiley   +1 more source

Scientometric Analysis of Toxicology in Asia Pacific Region: Signs of Growth [PDF]

open access: yesAsia Pacific Journal of Medical Toxicology, 2014
Background: In recent decades, the science of toxicology in Asia Pacific (AP) region has been expanding. In this study, the productivity of the science of toxicology in the timeframe of the years 1996 to 2013 in AP region was evaluated and was compared ...
Reza Afshari
doaj  

Public health and public law issues for the toxicological risk assessment of chemical mixtures

open access: yesPublic Health and Toxicology, 2021
Humans are simultaneously exposed to a near-infinite number of substances of both nutritional and toxicological interest. While traditional risk assessment has been based on the evaluation of effects of single substances, real-life exposure is ...
Silvio Roberto Vinceti   +1 more
doaj   +1 more source

Distribution, Ecology, Chemistry and Toxicology of Plant Stinging Hairs [PDF]

open access: gold, 2021
Hans‐Jürgen Ensikat   +3 more
openalex   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

open access: yesFEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso   +4 more
wiley   +1 more source

Systems biology and synthetic biology: A new epoch for toxicology research [PDF]

open access: yes, 2014
Copyright © 2015 Mark T. Mc Auley et al. This is an open access article distributed under the Creative Commons Attribution License 3.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly ...
Choi, Hyunok   +4 more
core   +7 more sources

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