Suction conditions for minimizing the production of free hemoglobin during blood salvage using an autotransfusion apparatus [PDF]
Korean Journal of Anesthesiology, 2011 BackgroundThree kinds of conditions should be considered to reduce free hemoglobin production using an autologous cell salvage device. They are the negative suction pressure, the size of suction tip, and the air contact during suction. We want to examine
Sang-Bum An, Eun Su Choi, Wonsik Ahn
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Claiming trend in toxicological and pharmacological dose-response studies: an overview on statistical methods and related R-Software [PDF]
arXiv, 2020 There are very different statistical methods for demonstrating a trend in pharmacological experiments. Here, the focus is on sparse models with only one parameter to be estimated and interpreted: the increase in the regression model and the difference to control in the contrast model.
arxiv
Evaluation of histological findings with severity grade, to analyze toxicology in-vivo studies [PDF]
arXiv, 2022 In-vivo toxicological studies are characterized by multiple primary endpoints with quite different scales. Whereas guidelines and publications provide various statistical tests for normally distributed endpoints (such as organ weights) and proportions (such as tumor rates), few approaches are available for graded histopathological findings, such as 0, +
arxiv
A Machine Learning Model to Predict Drug Transfer Across the Human Placenta Barrier
Frontiers in Chemistry, 2021 The development of computational models for assessing the transfer of chemicals across the placental membrane would be of the utmost importance in drug discovery campaigns, in order to develop safe therapeutic options. We have developed a low-dimensional
Juan I. Di Filippo +6 more
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Benchmarking Toxic Molecule Classification using Graph Neural Networks and Few Shot Learning [PDF]
arXiv, 2023 Traditional methods like Graph Convolutional Networks (GCNs) face challenges with limited data and class imbalance, leading to suboptimal performance in graph classification tasks during toxicity prediction of molecules as a whole. To address these issues, we harness the power of Graph Isomorphic Networks, Multi Headed Attention and Free Large-scale ...
arxiv
ELIXIR and Toxicology: a community in development [version 2; peer review: 2 approved]
F1000Research, 2023 Toxicology has been an active research field for many decades, with academic, industrial and government involvement. Modern omics and computational approaches are changing the field, from merely disease-specific observational models into target-specific ...
Evan E. Bolton +59 more
doaj
Exposure assessment to support on-farm risk characterisation for pesticides [PDF]
, 2001 C. D. Brown, K. Lewis, and A. Hart, ‘Exposure assessment to support on-farm risk characterisation for pesticides’ paper presented at the European Meeting of the Society of Environmental Toxicology and Chemistry (SETAC), 26 -29 August 20001, Copenhagen ...
Brown, C.D., Hart, A., Lewis, Kathleen
core
Acta Medica, 2008 Lead is one of the oldest known and most widely studied occupational and environmental poison. Despite intensive study, there is still debate about the toxic effects of lead, both from low-level exposure in the general population owing to environmental ...
Jiří Patočka
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Review of: Lewis\u27 Dictionary of Toxicology (Robert A. Lewis, ed.; Lewis Publishers 1998) [PDF]
, 1999 Review of the book: Lewis\u27 Dictionary of Toxicology (Robert A. Lewis, ed.; Lewis Publishers 1998). About the author, acknowledgments, alphabetical listing of terms defined. ISBN 1-56670-223-2; [1127 pp. $84.95. Hardbound. 2000 Corporate Blvd.
Evans, Dana E.
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