Results 61 to 70 of about 258,157 (266)

Pesticide Mixture Poisoning: A Case Report

open access: yesArab Journal of Forensic Sciences & Forensic Medicine, 2018
Acute pesticide poisoning is a reported as major health problem worldwide and are reported mostly in cases of suicides and cases of unintentional poisoning are less in number. A significant number of cases are encountered in forensic science laboratories
Atul Bajaj   +3 more
doaj   +1 more source

Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models

open access: yesAdvanced Healthcare Materials, EarlyView.
This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre   +3 more
wiley   +1 more source

Network toxicology: A new science [PDF]

open access: yesComputational Ecology and Software, 2016
Network toxicology is related to network biology. Based on my previous study (Zhang, 2016c), in present article I further outlined and defined the aims, scope, theory and methodology of network toxicology.
WenJun Zhang
doaj  

Commentary on: Attafi IM, Albeishy MY, Oraiby ME, Khardali IA, Shaikhain GA, Fageeh MM. Postmortem Distribution of Cathinone and Cathine in Human Biological Specimens in a Case of Death Associated wit

open access: yesArab Journal of Forensic Sciences & Forensic Medicine, 2019
The interpretation of post-mortem human tissue toxicology levels may be affected by the sampling site chosen. It is important to bear this in mind when looking at the psychoactive constituents of khat (Catha edulis Forsk) that have been consumed and have
John M. Corkery   +2 more
doaj   +1 more source

A Tri‐Culture Heart‐on‐a‐Chip Platform With iPSC‐Derived Cardiac Cells for Predictive Cardiotoxicity Testing

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents the first entirely isogenic heart‐on‐chip, unifying cardiomyocytes, fibroblasts, and endothelial cells from a single iPSC source. The platform reveals a critical biological insight: the endothelium actively shields cardiac tissue from drug‐induced toxicity, challenging the predictive accuracy of conventional, avascular models for ...
Karine Tadevosyan   +12 more
wiley   +1 more source

A Cryoprotectant‐Compatible Nanoporous Platform for Stable and Scalable Delivery of Biopharmaceuticals

open access: yesAdvanced Materials, EarlyView.
A cryoprotectant‐compatible nanoporous platform enables ambient‐stable and scalable delivery of gene editing therapeutics. By combining hierarchical pore architecture with optimized lyophilization chemistry, the system preserves Cas9‐RNP activity post‐freeze‐drying.
Sian Lee   +8 more
wiley   +1 more source

Mechanistic evidence for dibutyl phthalate as an environmental trigger for inflammatory bowel disease

open access: yesiScience
Summary: Dibutyl phthalate (DBP) is a ubiquitous pollutant, but its molecular link to inflammatory bowel disease (IBD) is undefined. We employed an integrative network toxicology framework, combining DBP target databases with IBD patient transcriptomics ...
Hang Yuan   +3 more
doaj   +1 more source

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

open access: yesAdvanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Risk‐Benefit Assessment of Foods

open access: yesEFSA Journal, 2019
Food is an elementary requirement for human life, providing nutrients and essential energy needed for optimal health. But at the same time, food can also be a vehicle of hazardous substances or pathogens that could affect human health negatively.
National Food Institute, Technical University of Denmark (DTU Food), Denmark   +3 more
doaj   +1 more source

Surface‐Capped Protein Nanoparticles for Nonviral Gene Delivery

open access: yesAdvanced Materials, EarlyView.
ABSTRACT Developing simple, safe, and efficient nonviral delivery systems remains a significant challenge in bioengineering. Nanoparticles offer promising gene delivery capabilities with reduced toxicity; however, long‐standing challenges related to effective plasmid encapsulation and delivery exist.
Fjorela Xhyliu   +9 more
wiley   +1 more source

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