Results 91 to 100 of about 28,372 (204)

Diversity, Function and Activity of DNA Viruses in the Qiangyong Proglacial Lake Sediment, the Tibetan Plateau

open access: yesEnvironmental Microbiology Reports, Volume 18, Issue 1, February 2026.
This study identified DNA viruses from Qiangyong proglacial lake sediments on the Tibetan Plateau, revealing a highly diverse and previously uncharacterized viral community. These viruses influence microbial community structure and function by infecting key nutrient‐transforming taxa and encoding auxiliary metabolic genes that modulate host metabolism.
Yang Zhao   +6 more
wiley   +1 more source

Novel Single-Cell Method for Studying Toxin-Antitoxin Systems [PDF]

open access: yes, 2016
细菌的抗药性危害日益严重,毒素-抗毒素(TA)系统在细菌内的异质性表达是多药耐受性存留细胞形成的重要原因。阐明致病菌中毒素-抗毒素系统的作用机理和生理功能对研发防控致病菌的新策略和疾病诊断治疗等具有重要意义。目前,对TA系统的研究主要集中在基因水平或转录水平,而传统基于蛋白质水平的检测方法,如WesternBlot等都是对大量细菌裂解液中的毒素抗毒素蛋白进行检测,是大量细菌内毒素抗毒素蛋白表现的集权平均。对单细菌水平的毒素-抗毒素蛋白进行快速逐一分析可揭示因集权平均而被掩盖的个体差异 ...
宋毅怡
core  

Evolution of the Quorum network and the mobilome (plasmids and bacteriophages) in clinical strains of Acinetobacter baumannii during a decade [PDF]

open access: yes, 2018
In this study, we compared eighteen clinical strains of A. baumannii belonging to the ST-2 clone and isolated from patients in the same intensive care unit (ICU) in 2000 (9 strains referred to ...
Blasco, Lucía   +11 more
core   +2 more sources

Probiotic‐Based Materials as Living Therapeutics

open access: yesAdvanced Materials, Volume 38, Issue 1, 2 January 2026.
Recent advances in Engineered Living Materials are highlighted, integrating synthetic biology and advanced materials, with a focus on probiotic‐based therapeutics. Probiotic Living Materials hold great potential for biosensing, infection treatment, osteogenesis, wound healing, vaginal and gastrointestinal disorders, and cancer therapy. breakthroughs in
Laura Sabio   +2 more
wiley   +1 more source

A bacterial toxin-antitoxin module is the origin of inter-bacterial and inter-kingdom effectors of Bartonella. [PDF]

open access: yes, 2017
Host-targeting type IV secretion systems (T4SS) evolved from conjugative T4SS machineries that mediate interbacterial plasmid transfer. However, the origins of effectors secreted by these virulence devices have remained largely elusive.
Dehio, C.   +5 more
core   +4 more sources

Advances in Synchrotron Radiation‐Based Vacuum‐Ultraviolet Circular Dichroism for Biomolecular Structural Analysis

open access: yesChemistry – An Asian Journal, Volume 21, Issue 2, 28 January 2026.
Vacuum‐ultraviolet circular dichroism spectroscopy using synchrotron radiation is operated at the Research Institute for Synchrotron Radiation Science (HiSOR), Hiroshima University. By combining the circular dichroism technique with bioinformatics, molecular dynamics, and linear dichroism, the spectral analysis methods have been advanced, enabling ...
Koichi Matsuo   +3 more
wiley   +1 more source

Caracterização da interação HipAB na Shewanella oneidensis MR1 [PDF]

open access: yes, 2013
Mestrado em BioquímicaBacterial resistance is a major issue in research related to environmental and public health, due to the ineffectiveness of antibiotics, resulting from a subpopulation of bacterial cells entering a dormant state.
Henriques, Andreia Filipa Pereira
core  

A marine plasmid hitchhiking vast phylogenetic and geographic distances [PDF]

open access: yes, 2019
Horizontal gene transfer (HGT) plays an important role in bacterial evolution and serves as a driving force for bacterial diversity and versatility. HGT events often involve mobile genetic elements like plasmids, which can promote their own dissemination
Alexandra M. Howat   +21 more
core   +2 more sources

Structure Modeling Protocols for Protein Multimer and RNA in CASP16 With Enhanced MSAs, Model Ranking, and Deep Learning

open access: yesProteins: Structure, Function, and Bioinformatics, Volume 94, Issue 1, Page 167-182, January 2026.
ABSTRACT We present the methods and results of our protein complex and RNA structure predictions at CASP16. Our approach integrated multiple state‐of‐the‐art deep learning models with a consensus‐based scoring method. To enhance the depth of multiple sequence alignments (MSAs), we employed a large metagenomic sequence database.
Yuki Kagaya   +10 more
wiley   +1 more source

The DarTG toxin-antitoxin system provides phage defense by ADP-ribosylating viral DNA [PDF]

open access: gold, 2021
Michele LeRoux   +8 more
openalex   +1 more source

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