Results 91 to 100 of about 25,002 (218)
CHR exhibited significant protective effects against ACR‐induced hepatotoxicity by reducing oxidative stress, decreasing inflammation and apoptosis, and inhibiting autophagic activity, highlighting its potential as an effective therapeutic agent. ABSTRACT Acrylamide (ACR) is a toxic chemical with a high carcinogenic risk that is released as a result of
Selman Gencer+6 more
wiley +1 more source
Multiple Toxin-Antitoxin Systems in Mycobacterium tuberculosis [PDF]
The hallmark of Mycobacterium tuberculosis is its ability to persist for a long-term in host granulomas, in a non-replicating and drug-tolerant state, and later awaken to cause disease. To date, the cellular factors and the molecular mechanisms that mediate entry into the persistence phase are poorly understood. Remarkably, M.
Patricia Bordes+2 more
openaire +4 more sources
The ζ toxin induces a set of protective responses and dormancy. [PDF]
The ζε module consists of a labile antitoxin protein, ε, which in dimer form (ε(2)) interferes with the action of the long-living monomeric ζ phosphotransferase toxin through protein complex formation.
Virginia S Lioy+6 more
doaj +1 more source
Bakterije su razvile iznimnu sposobnost prilagodbe na različite životne uvjete. Uz pomoć raznih sustava i mehanizama daju brz stanični odgovor na stresore, tretman antibiotikom, stanje gladi i ostale nepovoljne uvjete. Jedan takav sustav pronađen je u
Matković, Katarina
core +2 more sources
AcrDB update: Predicted 3D structures of anti‐CRISPRs in human gut viromes
Abstract Anti‐CRISPR (Acr) proteins play a key role in phage‐host interactions and hold great promise for advancing genome‐editing technologies. However, finding new Acrs has been challenging due to their low sequence similarity. Recent advances in protein structure prediction have opened new pathways for Acr discovery by using 3D structure similarity.
Minal Khatri+4 more
wiley +1 more source
Food‐derived bioactive peptides with anti‐diabetic and antimicrobial potential: An updated review on current trends and challenges. ABSTRACT The exploration of bioactive peptides derived from diverse food sources demonstrates their potential to provide advantages beyond basic nutrition, such as immunological support, antibacterial activities, and ...
Prashantkumar Natubhai Padhiyar+3 more
wiley +1 more source
Comparative Genomics of 9 Novel Paenibacillus Larvae Bacteriophages [PDF]
American Foulbrood Disease, caused by the bacterium Paenibacillus larvae, is one of the most destructive diseases of the honeybee, Apis mellifera. Our group recently published the sequences of 9 new phages with the ability to infect and lyse P.
Amy, Penny S.+4 more
core +2 more sources
ABSTRACT This study aims to investigate the antioxidant and iron chelating activities; phytochemical composition; and profile, antibiofilm activity, in silico molecular docking, and network analysis of the methanol extract of Amaranthus retroflexus. The extract showed an IC₅₀ value of 3.50 mg/mL in the DPPH assay and 6.61 mg/mL in the iron‐chelating ...
Mehmet Aytar+5 more
wiley +1 more source
Molecular processes underlying synergistic linuron mineralization in a triple-species bacterial consortium biofilm revealed by differential transcriptomics [PDF]
The proteobacteria Variovorax sp. WDL1, Comamonas testosteroni WDL7, and Hyphomicrobium sulfonivorans WDL6 compose a triple-species consortium that synergistically degrades and grows on the phenylurea herbicide linuron.
Anders+52 more
core +2 more sources
The Quest for Antibodies and Other Acquired Immune Receptors: A Historical Perspective
ABSTRACT The diversity of antibody molecules has for decades been an unsolved enigma that has attracted wide interest among biologists. Parallel to the accumulation of experimental evidence, progress in antibody research was also driven by the theoretical debate that played a particularly prominent role, at least until the entry of molecular biology ...
Andrea De Lerma Barbaro+5 more
wiley +1 more source