Results 91 to 100 of about 25,002 (218)

The Protective Effects of Chrysin on Acrylamide‐Induced Hepatotoxicity: Insights Into Oxidative Stress, Inflammation, Apoptosis, Autophagy, and Histological Evaluation in Rats

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 39, Issue 6, June 2025.
CHR exhibited significant protective effects against ACR‐induced hepatotoxicity by reducing oxidative stress, decreasing inflammation and apoptosis, and inhibiting autophagic activity, highlighting its potential as an effective therapeutic agent. ABSTRACT Acrylamide (ACR) is a toxic chemical with a high carcinogenic risk that is released as a result of
Selman Gencer   +6 more
wiley   +1 more source

Multiple Toxin-Antitoxin Systems in Mycobacterium tuberculosis [PDF]

open access: yesToxins, 2014
The hallmark of Mycobacterium tuberculosis is its ability to persist for a long-term in host granulomas, in a non-replicating and drug-tolerant state, and later awaken to cause disease. To date, the cellular factors and the molecular mechanisms that mediate entry into the persistence phase are poorly understood. Remarkably, M.
Patricia Bordes   +2 more
openaire   +4 more sources

The ζ toxin induces a set of protective responses and dormancy. [PDF]

open access: yesPLoS ONE, 2012
The ζε module consists of a labile antitoxin protein, ε, which in dimer form (ε(2)) interferes with the action of the long-living monomeric ζ phosphotransferase toxin through protein complex formation.
Virginia S Lioy   +6 more
doaj   +1 more source

Toxin-antitoxin system [PDF]

open access: yes, 2018
Bakterije su razvile iznimnu sposobnost prilagodbe na različite životne uvjete. Uz pomoć raznih sustava i mehanizama daju brz stanični odgovor na stresore, tretman antibiotikom, stanje gladi i ostale nepovoljne uvjete. Jedan takav sustav pronađen je u
Matković, Katarina
core   +2 more sources

AcrDB update: Predicted 3D structures of anti‐CRISPRs in human gut viromes

open access: yesProtein Science, Volume 34, Issue 6, June 2025.
Abstract Anti‐CRISPR (Acr) proteins play a key role in phage‐host interactions and hold great promise for advancing genome‐editing technologies. However, finding new Acrs has been challenging due to their low sequence similarity. Recent advances in protein structure prediction have opened new pathways for Acr discovery by using 3D structure similarity.
Minal Khatri   +4 more
wiley   +1 more source

Food‐Derived Bioactive Peptides With Anti‐Diabetic and Antimicrobial Potential: An Updated Review on Current Trends and Challenges

open access: yesSustainable Food Proteins, Volume 3, Issue 2, June 2025.
Food‐derived bioactive peptides with anti‐diabetic and antimicrobial potential: An updated review on current trends and challenges. ABSTRACT The exploration of bioactive peptides derived from diverse food sources demonstrates their potential to provide advantages beyond basic nutrition, such as immunological support, antibacterial activities, and ...
Prashantkumar Natubhai Padhiyar   +3 more
wiley   +1 more source

Comparative Genomics of 9 Novel Paenibacillus Larvae Bacteriophages [PDF]

open access: yes, 2016
American Foulbrood Disease, caused by the bacterium Paenibacillus larvae, is one of the most destructive diseases of the honeybee, Apis mellifera. Our group recently published the sequences of 9 new phages with the ability to infect and lyse P.
Amy, Penny S.   +4 more
core   +2 more sources

Investigation of the Antioxidant, Antibiofilm, and Endocrine‐disrupting Potential of Amaranthus retroflexus Methanol Extract Used as Food: Network and Molecular Docking Analyses

open access: yesJournal of Food Science, Volume 90, Issue 6, June 2025.
ABSTRACT This study aims to investigate the antioxidant and iron chelating activities; phytochemical composition; and profile, antibiofilm activity, in silico molecular docking, and network analysis of the methanol extract of Amaranthus retroflexus. The extract showed an IC₅₀ value of 3.50 mg/mL in the DPPH assay and 6.61 mg/mL in the iron‐chelating ...
Mehmet Aytar   +5 more
wiley   +1 more source

Molecular processes underlying synergistic linuron mineralization in a triple-species bacterial consortium biofilm revealed by differential transcriptomics [PDF]

open access: yes, 2018
The proteobacteria Variovorax sp. WDL1, Comamonas testosteroni WDL7, and Hyphomicrobium sulfonivorans WDL6 compose a triple-species consortium that synergistically degrades and grows on the phenylurea herbicide linuron.
Anders   +52 more
core   +2 more sources

The Quest for Antibodies and Other Acquired Immune Receptors: A Historical Perspective

open access: yesInternational Journal of Immunogenetics, Volume 52, Issue 3, Page 125-134, June 2025.
ABSTRACT The diversity of antibody molecules has for decades been an unsolved enigma that has attracted wide interest among biologists. Parallel to the accumulation of experimental evidence, progress in antibody research was also driven by the theoretical debate that played a particularly prominent role, at least until the entry of molecular biology ...
Andrea De Lerma Barbaro   +5 more
wiley   +1 more source

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