Results 121 to 130 of about 295,113 (307)
The FEBS Journal, 2020 In Mycobacterium tuberculosis (Mtb), the Clp protease degradation pathway, mediated by the modular ClpCP and ClpXP protease complexes, is essential for growth and presents an attractive drug target.
Michal Ziemski +4 more
semanticscholar +1 more source
The Streptococcus pneumoniae pezAT toxin-antitoxin system reduces β-Lactam resistance and genetic competence [PDF]
, 2016 13 p.-6 fig.Chromosomally encoded Type II Toxin-Antitoxin operons are ubiquitous in bacteria and archaea. Antitoxins neutralize the toxic effect of cognate Toxins by protein-protein interactions and sequestering the active residues of the Toxin.
Chan, Wai Ting, Espinosa, Manuel
core +2 more sources
Bacterial toxin-antitoxin systems [PDF]
Mobile Genetic Elements, 2011 Toxin-antitoxin (TA) systems are composed of two elements: a toxic protein and an antitoxin which is either an RNA (type I and III) or a protein (type II). Type II systems are abundant in bacterial genomes in which they move via horizontal gene transfer.
Guglielmini, Julien +1 more
openaire +4 more sources
New Phytologist, EarlyView.Summary Plasmids contribute to the efficient adaptation of bacteria to specific niches in nature. The gram‐positive bacterium Clavibacter michiganensis carries two plasmid‐borne important virulence genes, celA and pat‐1, necessary for wilting in tomato. The 88 C.
In Sun Hwang +8 more
wiley +1 more source
Prophage encoding toxin/antitoxin system PfiT/PfiA inhibits Pf4 production in Pseudomonas aeruginosa
Microbial Biotechnology, 2020 Pf prophages are ssDNA filamentous prophages that are prevalent among various Pseudomonas aeruginosa strains. The genomes of Pf prophages contain not only core genes encoding functions involved in phage replication, structure and assembly but also ...
Yangmei Li +5 more
semanticscholar +1 more source
Multiple Toxin-Antitoxin Systems in Mycobacterium tuberculosis [PDF]
Toxins, 2014 The hallmark of Mycobacterium tuberculosis is its ability to persist for a long-term in host granulomas, in a non-replicating and drug-tolerant state, and later awaken to cause disease. To date, the cellular factors and the molecular mechanisms that mediate entry into the persistence phase are poorly understood. Remarkably, M.
Patricia Bordes +2 more
openaire +4 more sources
IbPIF1 confers stem nematode resistance by regulating secondary metabolites in sweet potato
Plant Biotechnology Journal, EarlyView.Summary The stem nematode (Ditylenchus destructor Thorne) is a pervasive and destructive plant‐parasitic nematode worldwide, inflicting severe agricultural and economic losses in a wide range of crops. Despite its global impact, the molecular mechanisms underlying plant resistance to this pathogen remain poorly understood. Our previous studies in sweet
Nan Nie +14 more
wiley +1 more source
Novel polyadenylylation-dependent neutralization mechanism of the HEPN/MNT toxin/antitoxin system
Nucleic Acids Research, 2020 The two-gene module HEPN/MNT is predicted to be the most abundant toxin/antitoxin (TA) system in prokaryotes. However, its physiological function and neutralization mechanism remains obscure.
Jianyun Yao +10 more
semanticscholar +1 more source
, 2018 Bakterije su razvile iznimnu sposobnost prilagodbe na različite životne uvjete. Uz pomoć raznih sustava i mehanizama daju brz stanični odgovor na stresore, tretman antibiotikom, stanje gladi i ostale nepovoljne uvjete. Jedan takav sustav pronađen je u
Matković, Katarina
core +2 more sources
Phylogenetic identification of bacterial MazF toxin protein motifs among probiotic strains and foodborne pathogens and potential implications of engineered probiotic intervention in food [PDF]
, 2012 BACKGROUND: Toxin-antitoxin (TA) systems are commonly found in bacteria and Archaea, and it is the most common mechanism involved in bacterial programmed cell death or apoptosis. Recently, MazF, the toxin component of the toxin-antitoxin module, has been
Jing Hu +4 more
core +1 more source