Results 171 to 180 of about 26,624 (220)

Analysis of co-occurrence of type II toxin-antitoxin systems and antibiotic resistance determinants in <i>Staphylococcus aureus</i>. [PDF]

open access: yesmSystems
Bukowski M   +8 more
europepmc   +1 more source

Membrane selectivity and pore formation of SprA1 and SprA2 hemolytic peptides from Staphylococcus aureus type I toxin-antitoxin systems. [PDF]

open access: yesFEBS J
Fermon L   +10 more
europepmc   +1 more source
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Prokaryotic toxin–antitoxin stress response loci

Nature Reviews Microbiology, 2005
Although toxin-antitoxin gene cassettes were first found in plasmids, recent database mining has shown that these loci are abundant in free-living prokaryotes, including many pathogenic bacteria. For example, Mycobacterium tuberculosis has 38 chromosomal toxin-antitoxin loci, including 3 relBE and 9 mazEF loci. RelE and MazF are toxins that cleave mRNA
Kenn Gerdes, Anders Løbner-Olesen
exaly   +4 more sources

TOXIN-ANTITOXIN

Journal of the American Medical Association, 1926
Toxin-antitoxin mixture, as now made in accordance with the technic of Park1and his assistants, has proved itself remarkably free of the protein element from the clinical as well as the laboratory standpoint. A five year clinical study has proved satisfactorily the inability of toxin-antitoxin to sensitize individuals to horse protein; this conclusion ...
EDWARD L. BAUER, H. B. WILMER
openaire   +1 more source

TOXIN-ANTITOXIN IMMUNIZATION

Journal of the American Medical Association, 1927
In October, 1925, the health department of Kansas City, in conjunction and cooperation with the school board, undertook to inaugurate a campaign for the prevention of diphtheria. Having a good understanding of conditions in the past, particularly with respect to contagious diseases here, we estimated that if we could reach 20 per cent of the total ...
JOHN L. LAVAN, E. C. BLACK
openaire   +1 more source

Toxins-antitoxins: diversity, evolution and function

Critical Reviews in Biochemistry and Molecular Biology, 2011
Genes for toxin-antitoxin (TA) complexes are widespread in prokaryote genomes, and species frequently possess tens of plasmid and chromosomal TA loci. The complexes are categorized into three types based on genetic organization and mode of action.
Hayes, Finbarr, Van Melderen, Laurence
openaire   +2 more sources

Bacterial Persistence and Toxin-Antitoxin Loci

Annual Review of Microbiology, 2012
Bacterial persistence is caused by the presence of rare, slowly growing bacteria among populations of rapidly growing cells. The slowly growing bacteria are tolerant of antibiotics and other environmental insults, whereas their isogenic, rapidly growing siblings are sensitive.
Gerdes K, Maisonneuve E
openaire   +3 more sources

Ribonucleases in bacterial toxin–antitoxin systems

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2013
Toxin-antitoxin (TA) systems are widespread in bacteria and archaea and play important roles in a diverse range of cellular activities. TA systems have been broadly classified into 5 types and the targets of the toxins are diverse, but the most frequently used cellular target is mRNA.
Cook, Gregory M.   +6 more
openaire   +3 more sources

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