Chemistry – An Asian Journal, Volume 21, Issue 2, 28 January 2026.Vacuum‐ultraviolet circular dichroism spectroscopy using synchrotron radiation is operated at the Research Institute for Synchrotron Radiation Science (HiSOR), Hiroshima University. By combining the circular dichroism technique with bioinformatics, molecular dynamics, and linear dichroism, the spectral analysis methods have been advanced, enabling ...
Koichi Matsuo +3 more
wiley +1 more source
The Influence of the Toxin/Antitoxin mazEF on Growth and Survival of Listeria monocytogenes under Stress [PDF]
, 2017 A major factor in the resilience of Listeria monocytogenes is the alternative sigma factor B (σB). Type II Toxin/Antitoxin (TA) systems are also known to have a role in the bacterial stress response upon activation via the ClpP or Lon proteases. Directly
Curtis, Thomas +3 more
core +2 more sources
Evolution of the SpoIISABC Toxin-Antitoxin-Antitoxin System in Bacilli
Toxins, 2016 Programmed cell death in bacteria is generally associated with two-component toxin-antitoxin systems. The SpoIISABC system, originally identified in Bacillus subtilis, consists of three components: a SpoIISA toxin and the SpoIISB and SpoIISC antitoxins ...
Marek Gabriško, Imrich Barák
doaj +1 more source
Phylogenetic identification of bacterial MazF toxin protein motifs among probiotic strains and foodborne pathogens and potential implications of engineered probiotic intervention in food [PDF]
, 2012 BACKGROUND: Toxin-antitoxin (TA) systems are commonly found in bacteria and Archaea, and it is the most common mechanism involved in bacterial programmed cell death or apoptosis. Recently, MazF, the toxin component of the toxin-antitoxin module, has been
Jing Hu +4 more
core +1 more source
Bistability in type I toxin-antitoxin systems may lead to stress-induced persister formation
npj Systems Biology and ApplicationsAntibiotic persistence, characterized by a dormant subpopulation of bacterial cells that causes chronic and recurrent infections, remains poorly understood despite being recognized nearly a century ago. Toxin–antitoxin (TA) systems, which include a toxin
Sofija Markovic +3 more
doaj +1 more source
PLoS ONE, 2012 Bacterial toxin-antitoxin (TA) systems encode two proteins, a potent inhibitor of cell proliferation (toxin) and its specific antidote (antitoxin). Structural data has revealed striking similarities between the two model TA toxins CcdB, a DNA gyrase ...
Andrew B Smith +8 more
doaj +1 more source
Chromosomal toxin-antitoxin systems in Pseudomonas putida are rather selfish than beneficial [PDF]
, 2020 Sirli Rosendahl +4 more
openalex +1 more source
Resonant activation: a strategy against bacterial persistence
, 2010 A bacterial colony may develop a small number of cells genetically identical to, but phenotypically different from other normally growing bacteria. These so-called persister cells keep themselves in a dormant state and thus are insensitive to antibiotic ...
Hanggi P +4 more
core +1 more source
Cassette recombination dynamics within chromosomal integrons are regulated by toxin–antitoxin systems [PDF]
, 2022 Egill Richard +16 more
openalex +1 more source
Bacterial Toxin–Antitoxin Systems: More Than Selfish Entities?
PLoS Genetics, 2009 Bacterial toxin-antitoxin (TA) systems are diverse and widespread in the prokaryotic kingdom. They are composed of closely linked genes encoding a stable toxin that can harm the host cell and its cognate labile antitoxin, which protects the host from the toxin's deleterious effect.
Van Melderen, Laurence +1 more
openaire +5 more sources