Results 131 to 140 of about 23,162 (212)

Development of an antibiotic marker-free platform for heterologous protein production in Streptomyces

open access: yesMicrobial Cell Factories, 2017
Background The industrial use of enzymes produced by microorganisms is continuously growing due to the need for sustainable solutions. Nevertheless, many of the plasmids used for recombinant production of proteins in bacteria are based on the use of ...
Laura Sevillano   +2 more
doaj   +1 more source

Comparative genomic analysis of Acinetobacter spp. plasmids originating from clinical settings and environmental habitats [PDF]

open access: yes, 2018
Bacteria belonging to the genus Acinetobacter have become of clinical importance over the last decade due to the development of a multi-resistant phenotype and their ability to survive under multiple environmental conditions.
Pistorio, Mariano   +5 more
core   +2 more sources

The Toxin of VapBC-1 Toxin-Antitoxin Module from Leptospira interrogans Is a Ribonuclease That Does Not Arrest Bacterial Growth but Affects Cell Viability

open access: yesMicroorganisms
Bacterial ubiquitous Toxin-Antitoxin (TA) systems are considered to be important survival mechanisms during stress conditions. In regular environmental conditions, the antitoxin blocks the toxin, whereas during imbalanced conditions, the antitoxin ...
Deborah K. Damiano   +6 more
doaj   +1 more source

Geometric Properties of Isostables and Basins of Attraction of Monotone Systems [PDF]

open access: yes, 2017
In this paper, we study geometric properties of basins of attraction of monotone systems. Our results are based on a combination of monotone systems theory and spectral operator theory.
Mauroy, Alexandre, Sootla, Aivar
core   +3 more sources

The ng_ζ1 toxin of the gonococcal epsilon/zeta toxin/antitoxin system drains precursors for cell wall synthesis

open access: yesNature Communications, 2018
Toxin–antitoxin (TA) systems are important modulators of bacterial physiology. Here, the authors structurally characterize the epsilon/zeta TA system from the Gram-negative pathogen Neisseria gonorrhoeae and show that the toxin interferes with ...
Andrea Rocker   +5 more
doaj   +1 more source

Caracterização da interação HipAB na Shewanella oneidensis MR1 [PDF]

open access: yes, 2013
Mestrado em BioquímicaBacterial resistance is a major issue in research related to environmental and public health, due to the ineffectiveness of antibiotics, resulting from a subpopulation of bacterial cells entering a dormant state.
Henriques, Andreia Filipa Pereira
core  

Novel type II toxin-antitoxin systems with VapD-like proteins

open access: yesmBio
Type II toxin-antitoxin (TA) systems are widespread in prokaryotes. They consist of neighboring genes encoding two small proteins: a toxin that inhibits a critical cellular process and an antitoxin that binds to and neutralizes the toxin.
Konstantin Gilep   +6 more
doaj   +1 more source

The Role of Scientific Discovery in the Establishment of the First Biological Weapons Programmes [PDF]

open access: yes, 2005
YesThis report addresses the scientific and technological discoveries in the biological sciences that enabled the early interest in biological warfare to move from hurling infected corpses into enemy cities in ancient times, through use of small cultures
Davison, N.
core  

Type II Toxin-Antitoxin Systems in Escherichia coli

open access: yesInfection and Drug Resistance
The toxin-antitoxin (TA) system is widespread in prokaryotes and archaea, comprising toxins and antitoxins that counterbalance each other. Based on the nature and mode of action of antitoxins, they are classified into eight groups (type I to VIII). Both the toxins and the antitoxins are proteins in type II TA systems, and the antitoxin gene is usually ...
He Zhang   +7 more
openaire   +3 more sources

Population regulation in microbial consortia using dual feedback control [PDF]

open access: yes, 2017
An ongoing area of study in synthetic biology has been the design and construction of synthetic circuits that maintain homeostasis at the population level.
Baetica, Ania-Ariadna   +3 more
core  

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