Results 121 to 130 of about 17,352,598 (197)

Type II Toxin-Antitoxin Systems in Escherichia coli [PDF]

He Zhang,1 Shuan Tao,2 Huimin Chen,2 Yewei Fang,2 Yao Xu,3 A-Xiang Han,2 Fang Ma,1,* Wei Liang2,* 1Department of Medical Laboratory, Bengbu Medical University, Bengbu, Anhui, People’s Republic of China; 2Department of Clinical Laboratory, The ...
Fang Y, Han AX, Liang W, Zhang H, Tao S, Chen H, Ma F, Xu Y   +7 more
core  

A common origin for the bacterial toxin-antitoxin systems parD and ccd, suggested by analyses of toxin/target and toxin/antitoxin interactions.

PLoS ONE, 2012
Bacterial toxin-antitoxin (TA) systems encode two proteins, a potent inhibitor of cell proliferation (toxin) and its specific antidote (antitoxin). Structural data has revealed striking similarities between the two model TA toxins CcdB, a DNA gyrase ...
Andrew B Smith, Juan López-Villarejo, Elizabeth Diago-Navarro, Lesley A Mitchenall, Arjan Barendregt, Albert J Heck, Marc Lemonnier, Anthony Maxwell, Ramón Díaz-Orejas   +8 more
doaj   +1 more source

Toxin–Antitoxin Systems in Pathogenic Bacteria

, 2021
© 2021 by the authorToxin–antitoxin (TA) systems, which are ubiquitously present in plasmids, bacterial and archaeal genomes, are classified as types I to VI, according to the nature of the antitoxin and to the mode of toxin inhibition [1–5].
Alonso, Juan Carlos, Juan C. Alonso
core   +1 more source

Toxin-antitoxin system [PDF]

, 2018
Bakterije su razvile iznimnu sposobnost prilagodbe na različite životne uvjete. Uz pomoć raznih sustava i mehanizama daju brz stanični odgovor na stresore, tretman antibiotikom, stanje gladi i ostale nepovoljne uvjete. Jedan takav sustav pronađen je u
Matković, Katarina
core  

prlF and yhaV encode a new toxin-antitoxin system in Escherichia coli.

, 2007
Toxin-antitoxin systems consist of a stable toxin, frequently with endonuclease activity, and a small, labile antitoxin, which sequesters the toxin into an inactive complex.
Lupas, A. ; https://orcid.org/, Djuranovic, Sergej, Djuranovic, S., Hand, N.J., Schuenemann, V., Schmidt, O., Silhavy, T., Lupas, Andrei, Silhavy, T.J., Martin, Joerg, Hand, N., Schuenemann, Verena, Martin, J. ; https://orcid.org/   +12 more
core   +1 more source

Regulation of toxin-antitoxin systems by proteolysis. [PDF]

, 2013
Toxin-antitoxin systems are widely distributed among many bacterial species, including human pathogens. Regulation of type II TA system functions, where both components are proteins, relies on proteolysis.
Brzozowska, Iwona, Zielenkiewicz, Urszula   +1 more
core   +1 more source

Higher-Order Structure in Bacterial VapBC Toxin-Antitoxin Complexes

, 2017
Toxin-antitoxin systems are widespread in the bacterial kingdom, including in pathogenic species, where they allow rapid adaptation to changing environmental conditions through selective inhibition of key cellular processes, such as DNA replication or ...
Brodersen, Ditlev E, Ditlev E. Brodersen, Bendtsen, Kirstine L, Kirstine L. Bendtsen   +3 more
core   +1 more source

Development of an antibiotic marker-free platform for heterologous protein production in Streptomyces

Microbial Cell Factories, 2017
Background The industrial use of enzymes produced by microorganisms is continuously growing due to the need for sustainable solutions. Nevertheless, many of the plasmids used for recombinant production of proteins in bacteria are based on the use of ...
Laura Sevillano, Margarita Díaz, Ramón I. Santamaría   +2 more
doaj   +1 more source

RNA editing in bacteria recodes multiple proteins and regulates an evolutionarily conserved toxin-antitoxin system

Genome Research, 2017
Adenosine (A) to inosine (I) RNA editing is widespread in eukaryotes. In prokaryotes, however, A-to-I RNA editing was only reported to occur in tRNAs but not in protein-coding genes. By comparing DNA and RNA sequences of Escherichia coli, we show for the
Dan Bar-Yaacov, Ernest Mordret, R. Towers, Tammy Biniashvili, Clara Soyris, S. Schwartz, Orna Dahan, Y. Pilpel   +7 more
semanticscholar   +1 more source

Chaperone addiction of toxin–antitoxin systems

, 2016
International audienceBacterial toxin–antitoxin (TA) systems, in which a labile antitoxin binds and inhibits the toxin, can promote adaptation and persistence by modulating bacterial growth in response to stress.
Bordes, Patricia, Slama, Nawel, Genevaux, Pierre, Sala, Ambre Julie, Cirinesi, Anne-Marie, Guillet, Valérie, Mourey, Lionel, Ayala, Sara, Texier, Pauline   +8 more
core   +1 more source