Results 121 to 130 of about 28,880 (211)
Solar–Chemical Hybrid‐Driven Phototroph for Biosynthesis
Rare Metals, Volume 45, Issue 8, August 2026.
Shuo Liu, Shilong Chen, Xijun Liu
wiley +1 more source
Bistability in type I toxin-antitoxin systems may lead to stress-induced persister formation
npj Systems Biology and ApplicationsAntibiotic persistence, characterized by a dormant subpopulation of bacterial cells that causes chronic and recurrent infections, remains poorly understood despite being recognized nearly a century ago. Toxin–antitoxin (TA) systems, which include a toxin
Sofija Markovic +3 more
doaj +1 more source
PLoS ONE, 2012 Bacterial toxin-antitoxin (TA) systems encode two proteins, a potent inhibitor of cell proliferation (toxin) and its specific antidote (antitoxin). Structural data has revealed striking similarities between the two model TA toxins CcdB, a DNA gyrase ...
Andrew B Smith +8 more
doaj +1 more source
Automated discovery and phylogenetic analysis of new toxin-antitoxin systems. [PDF]
, 2008 Although often viewed as elements "at the service of" bacteria, plasmids exhibit replication and maintenance mechanisms that make them purely "selfish DNA" candidates.
Michel C Milinkovitch +8 more
core +1 more source
Type II toxin: antitoxin systems. More than small selfish entities? [PDF]
, 2016 Toxin-antitoxin (TA) modules regulate metabolism and viability of bacteria and archaea. In type II TA systems these functions are generally thought to be performed by two small proteins.
Rocker, A., Meinhart, A.
core +1 more source
The Prevalence and Diversity of Marine Toxin–Antitoxin Systems
Marine DrugsToxin-antitoxin (TA) systems, ubiquitous in bacterial and archaeal genomes, play pivotal roles in responding to environmental stresses, forming biofilms, defending against phages, and influencing pathogen virulence. The marine environment harbors Earth’s most diverse and abundant microbial communities, where microorganisms have evolved unique genetic ...
Cong Liu +5 more
openaire +3 more sources
Insights into toxin-antitoxin systems in the genus Bifidobacterium
Applied and Environmental MicrobiologyABSTRACT Toxin-antitoxin (TA) systems are widespread genetic modules in prokaryotes, implicated in diverse functions including stress adaptation, genome stability, and virulence. While extensively studied in pathogenic bacteria, their presence and roles in beneficial gut
Claudia Lefimil, Paula Bustamante
openaire +2 more sources
Microbial Cell Factories, 2017 Background The industrial use of enzymes produced by microorganisms is continuously growing due to the need for sustainable solutions. Nevertheless, many of the plasmids used for recombinant production of proteins in bacteria are based on the use of ...
Laura Sevillano +2 more
doaj +1 more source
A competence-regulated toxin-antitoxin system in Haemophilus influenzae [PDF]
, 2018 Natural competence allows bacteria to respond to environmental and nutritional cues by taking up free DNA from their surroundings, thus gaining nutrients and genetic information.
Rosemary J. Redfield +6 more
core +1 more source
Toxin-antitoxin Systems: Classification, Biological Function and Application in Biotechnology [PDF]
, 2014 The toxin-antitoxin (TA) systems are systems in which an unstable antitoxin inhibits a stable toxin. This review aims to introduce the TA system and its biological application in bacteria.
Raftari, M. +3 more
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