Results 101 to 110 of about 17,352,598 (197)

Patterns of Drug Resistance, Drug Resistance Conferring Mutations and Genomic DNA Methylation Revealed in Mycobacterium tuberculosis From South Africa

Tropical Medicine &International Health, EarlyView.
ABSTRACT Tuberculosis remains a major public health threat globally, with drug‐resistant strains undermining treatment efficacy. We analyzed 126 Mycobacterium tuberculosis (M. tuberculosis) isolates with diverse drug resistance spectra and selected 35 for whole genome sequencing (WGS) using Illumina NextSeq, SMRT PacBio Onso and SMRT PacBio Revio ...
Unarine Matodzi, Awelani Mutshembele, Eric Mensah, Dillon Muzondiwa, Ndivhuho A. Makhado, Oleg N. Reva   +5 more
wiley   +1 more source

Intrinsic Disorder as a New Frontier in Antimicrobial Resistance and Bacterial Fitness

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
The works examines the link between intrinsic disorder in bacterial protein structure, and bacterial function, and antimicrobial resistance. It highlights how flexible, disordered proteins support secretion, stress responses, desiccation protection, and virulence, while also suggesting that these adaptable regions may provide novel targets for ...
Jack O' Callaghan, Michael P. Ryan, Sarah Hudson, Damien Thompson   +3 more
wiley   +1 more source

Investigation of activity of acinetobacter baumannii toxin-antitoxin system antitoxin. [PDF]

, 2016
Investigation of Activity of Acinetobacter baumannii Toxin-antitoxin System Antitoxin Acinetobacter baumannii is a gram negative opportunistic pathogen which causes variety of nosocomial infections.
Čepauskas, Albinas,
core  

Asking the 5 W's for designing next‐generation bioprocessing

AIChE Journal, Volume 72, Issue 9, September 2026.
Abstract Biotechnology is expanding beyond traditional, centralized fermentation and toward next‐generation bioprocessing paradigms that emphasize flexible deployment outside the laboratory with application‐specific performance. However, many bioprocesses fail to translate beyond proof‐of‐concept into industrially viable systems because early design ...
Sangdo Yook, Karoline Maria Vieira Nogueira, Raj Sukumar, Jenna Miller, Hal S. Alper   +4 more
wiley   +1 more source

Toxin-Antitoxin Systems: A Key Role on Persister Formation in Salmonella enterica Serovar Typhimurium

Infection and Drug Resistance, 2022
Made Rai Dwitya Wiradiputra,1,2 Piyatip Khuntayaporn,1,3 Krit Thirapanmethee,1,3 Mullika Traidej Chomnawang1,3 1Antimicrobial Resistance Interdisciplinary Group (AmRIG), Faculty of Pharmacy, Mahidol University, Bangkok, Thailand; 2Biopharmaceutical ...
Wiradiputra MRD, Khuntayaporn P, Thirapanmethee K, Chomnawang MT   +3 more
doaj  

A competence-regulated toxin-antitoxin system in Haemophilus influenzae.

PLoS ONE, 2020
Natural competence allows bacteria to respond to environmental and nutritional cues by taking up free DNA from their surroundings, thus gaining both nutrients and genetic information.
Hailey Findlay Black, Scott Mastromatteo, Sunita Sinha, Rachel L Ehrlich, Corey Nislow, Joshua Chang Mell, Rosemary J Redfield   +6 more
doaj   +1 more source

A peptide of a type I toxin−antitoxin system induces Helicobacter pylori morphological transformation from spiral shape to coccoids

Proceedings of the National Academy of Sciences of the United States of America, 2019
Significance Helicobacter pylori, a gastric pathogen causing 800,000 deaths in the world annually, is encountered both in vitro and in patients as spiral-shaped bacteria and as round cells named coccoids.
L. El Mortaji, Alejandro Tejada-Arranz, A. Rifflet, I. G. Boneca, G. Péhau-Arnaudet, J. Radicella, S. Marsin, H. de Reuse   +7 more
semanticscholar   +1 more source

Genomic Insights Into the Multimetal Resilience and Biofilm‐Templated Nanorod Biosynthesis of Stenotrophomonas bentonitica BII‐R7: Bioremediation and Green Nanotechnology Implications

Microbial Biotechnology, Volume 19, Issue 9, September 2026.
Biofilm extracellular polymeric substances (EPS) in Stenotrophomonas bentonitica BII‐R7 direct the formation of crystalline trigonal selenium nanorods. Comparative genomics identifies a unique genetic toolkit underpinning EPS composition and metal resilience, positioning this strain as a platform for bioremediation and green nanomaterial synthesis ...
Eduardo Perez‐Muelas, Miguel Angel Ruiz‐Fresneda, Guillermo Lazuen‐Lopez, Tatiana Lopez‐Perez, Fouad Eddaoudi‐Lakraichi, Mohammed Bakkali, Mohamed Larbi Merroun   +6 more
wiley   +1 more source

Post-transcriptional deregulation of the tisB/istR-1 toxin-antitoxin system promotes SOS-independent persister formation in Escherichia coli.

Environmental Microbiology Reports, 2020
Bacterial dormancy is a valuable strategy to endure unfavourable conditions. The term 'persister' has been coined for cells that tolerate antibiotic treatments due to reduced cellular activity.
Daniel B. Edelmann, M. Oberpaul, T. Schäberle, Bork A. Berghoff   +3 more
semanticscholar   +1 more source

Protective and Pathogenic Antibodies to Citrullinated Antigens

Immunological Reviews, Volume 342, Issue 1, September 2026.
ABSTRACT Autoimmune diseases start years before clinical onset. In rheumatoid arthritis (RA), autoantibodies to citrullinated proteins (ACPA) and to modified IgG (rheumatoid factors, RF) can be detected many years before the inflammatory attack on cartilaginous joints. It has been assumed that these antibodies are pathogenic.
Outi Sareila, Yibo He, Zhongwei Xu, Changrong Ge, Erik Lönnblom, Rikard Holmdahl   +5 more
wiley   +1 more source